| scholarly article | Q13442814 |
| P50 | author | Jens Meiler | Q29315318 |
| David Nannemann | Q58887668 | ||
| Brian O. Bachmann | Q86531308 | ||
| P2093 | author name string | Kristian W Kaufmann | |
| P2860 | cites work | Protein Design by Directed Evolution | Q22065412 |
| Design of a Novel Globular Protein Fold with Atomic-Level Accuracy | Q22242282 | ||
| Purine nucleoside phosphorylase. 1. Structure-function studies | Q24313896 | ||
| De novo computational design of retro-aldol enzymes | Q24609401 | ||
| Transition state analogue discrimination by related purine nucleoside phosphorylases | Q24643026 | ||
| High-resolution structure prediction and the crystallographic phase problem | Q24646937 | ||
| Protein-DNA binding specificity predictions with structural models | Q24811023 | ||
| Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis | Q27629392 | ||
| Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase | Q27641894 | ||
| Structural basis for inhibition of human PNP by immucillin-H | Q27642104 | ||
| Structures of human purine nucleoside phosphorylase complexed with inosine and ddI | Q27642911 | ||
| Structure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding Affinities | Q27646507 | ||
| Kemp elimination catalysts by computational enzyme design | Q27650119 | ||
| Alteration of enzyme specificity by computational loop remodeling and design | Q27655618 | ||
| WebLogo: A Sequence Logo Generator | Q27860646 | ||
| Backbone-dependent rotamer library for proteins. Application to side-chain prediction | Q28267713 | ||
| Structural analyses reveal two distinct families of nucleoside phosphorylases | Q28366428 | ||
| A simple physical model for binding energy hot spots in protein-protein complexes | Q28914753 | ||
| Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool | Q30427274 | ||
| Computational method to reduce the search space for directed protein evolution | Q30660873 | ||
| Towards in silico lead optimization: scores from ensembles of protein/ligand conformations reliably correlate with biological activity | Q33262339 | ||
| Extending Iterative Protein Redesign and Optimization (IPRO) in protein library design for ligand specificity | Q33268494 | ||
| In vivo reshaping the catalytic site of nucleoside 2'-deoxyribosyltransferase for dideoxy- and didehydronucleosides via a single amino acid substitution | Q33335671 | ||
| Computational tools for designing and engineering biocatalysts | Q33419568 | ||
| Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase | Q33879137 | ||
| Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. | Q34910804 | ||
| Enzymatic transition states: thermodynamics, dynamics and analogue design | Q35974318 | ||
| Improving enzyme properties: when are closer mutations better? | Q36113206 | ||
| Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting | Q36909036 | ||
| Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies | Q37436023 | ||
| Examining the production costs of antiretroviral drugs | Q40294375 | ||
| Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle | Q41447443 | ||
| New algorithms and an in silico benchmark for computational enzyme design | Q42036773 | ||
| Enzymic determination of inorganic phosphates, organic phosphates and phosphate-liberating enzymes by use of nucleoside phosphorylase-xanthine oxidase (dehydrogenase)-coupled reactions. | Q42085849 | ||
| Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595. | Q42125891 | ||
| Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates | Q42256935 | ||
| Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases. | Q44759806 | ||
| Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: a vibrational spectroscopic study. | Q45005339 | ||
| Arthrobacter oxydans as a biocatalyst for purine deamination | Q46215757 | ||
| RosettaLigand docking with full ligand and receptor flexibility. | Q51861937 | ||
| ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility. | Q51933455 | ||
| Catalysis, binding and enzyme-substrate complementarity. | Q54055916 | ||
| Chemo-enzymatic syntheses of natural and unnatural 2'-deoxynucleosides | Q79082798 | ||
| Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test | Q81804014 | ||
| New therapies for hepatitis C virus infection | Q83148122 | ||
| P433 | issue | 8 | |
| P921 | main subject | directed evolution | Q440681 |
| P304 | page(s) | 607-616 | |
| P577 | publication date | 2010-06-04 | |
| P1433 | published in | Protein Engineering Design and Selection | Q15762396 |
| P1476 | title | Design and directed evolution of a dideoxy purine nucleoside phosphorylase | |
| P478 | volume | 23 |
| Q49165327 | Analysis of in vivo absorption of didanosine tablets in male adult dogs by HPLC. |
| Q35161643 | Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis. |
| Q27666415 | Bacillus cereus Phosphopentomutase Is an Alkaline Phosphatase Family Member That Exhibits an Altered Entry Point into the Catalytic Cycle |
| Q27682375 | Bioretrosynthetic construction of a didanosine biosynthetic pathway |
| Q30360853 | Computational approaches for rational design of proteins with novel functionalities |
| Q38104437 | Computational design gains momentum in enzyme catalysis engineering |
| Q37835947 | Computational design of protein-ligand interfaces: potential in therapeutic development |
| Q35555046 | Enantioselective enzymes by computational design and in silico screening |
| Q34925709 | Molecular cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of a purine nucleoside phosphorylase from Bacillus subtilis strain 168. |
| Q27677241 | Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. |
| Q38112629 | Small-molecule ligand docking into comparative models with Rosetta |
| Q31109061 | Using RosettaLigand for small molecule docking into comparative models |
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