Pharmacokinetics of tobramycin in adults with cystic fibrosis: implications for once-daily administration

scientific article

Pharmacokinetics of tobramycin in adults with cystic fibrosis: implications for once-daily administration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.44.4.809-813.2000
P932PMC publication ID89775
P698PubMed publication ID10722474
P5875ResearchGate publication ID12594401

P2093author name stringR W Jelliffe
B J Shapiro
A A Vinks
P M Beringer
P2860cites workShould clearance be normalised to body surface or to lean body mass?Q34448552
Efficacy, tolerance, and pharmacokinetics of once daily tobramycin for pseudomonas exacerbations in cystic fibrosisQ35259780
Killing and regrowth of bacteria in vitro: a review.Q37803210
Duration and clinical relevance of postantibiotic effect in relation to the dosing intervalQ39557342
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Single daily dosing of aminoglycosides.Q40477943
The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agentsQ40517235
Pharmacokinetic optimisation of antibacterial treatment in patients with cystic fibrosis. Current practice and suggestions for future directions.Q40829169
Exploration of once-daily dosing of aminoglycosides through Bayesian simulation.Q40947597
Management of pulmonary disease in patients with cystic fibrosisQ41002731
Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection modelsQ42169493
Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal modelQ43617611
Pharmacokinetic modelling of intravenous tobramycin in adolescent and adult patients with cystic fibrosis using the nonparametric expectation maximization (NPEM) algorithmQ44648863
Single, large, daily dosing versus intermittent dosing of tobramycin for treating experimental pseudomonas pneumoniaQ46611376
Once-daily vs. continuous aminoglycoside dosing: efficacy and toxicity in animal and clinical studies of gentamicin, netilmicin, and tobramycinQ46984010
A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems. Aerosolized Tobramycin Study Group.Q53971692
Pharmacodynamics of amikacin in vitro and in mouse thigh and lung infectionsQ54297609
Simultaneous antibiotic levels in "breakthrough" gram-negative rod bacteremiaQ54608322
Reduction of sputum Pseudomonas aeruginosa density by antibiotics improves lung function in cystic fibrosis more than do bronchodilators and chest physiotherapy aloneQ67285211
Lack of correlation between objective indicators and clinical-response scores during antimicrobial therapy for acute pulmonary exacerbations of cystic fibrosisQ67999563
Aminoglycoside penetration, inactivation, and efficacy in cystic fibrosis sputumQ69967341
Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumoniaQ70386358
Bioactivity of gentamicin in purulent sputum from patients with cystic fibrosis or bronchiectasis: comparison with activity in serumQ70459430
Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantationQ71703068
Tolerance, pharmacokinetics and efficacy of once daily amikacin for treatment of Pseudomonas aeruginosa pulmonary exacerbations in cystic fibrosis patientsQ71765938
Cystic fibrosisQ71767385
Postantibiotic effect in Pseudomonas aeruginosa following single and multiple aminoglycoside exposures in vitroQ72196470
Pharmacokinetics and bronchial diffusion of single daily dose amikacin in cystic fibrosis patientsQ73208219
Pharmacokinetics and safety of tobramycin after once-daily administration in patients with cystic fibrosisQ73875990
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
cystic fibrosisQ178194
P304page(s)809-813
P577publication date2000-04-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titlePharmacokinetics of tobramycin in adults with cystic fibrosis: implications for once-daily administration
P478volume44

Reverse relations

cites work (P2860)
Q39097052Comparing dosage adjustment methods for once-daily tobramycin in paediatric and adolescent patients with cystic fibrosis
Q38823748Evaluation of a Once/Day Tobramycin Regimen to Achieve Target Concentrations in Adult Patients with Cystic Fibrosis
Q44746169Evaluation of once daily tobramycin dosing in critically ill patients through Bayesian simulation
Q36191093Evaluation of serum concentrations achieved with an empiric once-daily tobramycin dosage regimen in children and adults with cystic fibrosis
Q55015958Extended Interval Tobramycin Pharmacokinetics in a Pediatric Patient With Primary Ciliary Dyskinesia Presenting With an Acute Respiratory Exacerbation.
Q37661512Extended-interval once-daily dosing of aminoglycosides in adult and pediatric patients with cystic fibrosis
Q42017846In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis
Q37149666Intensive care management of the patient with cystic fibrosis
Q63346417Monitoring of Tobramycin Exposure: What is the Best Estimation Method and Sampling Time for Clinical Practice?
Q38051316Once daily dosing of aminoglycosides in pediatric cystic fibrosis patients: a review of the literature
Q35738386Once-daily aminoglycoside dosing: An update on current literature
Q38133781Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: V. Aminoglycosides.
Q35557791Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis
Q35623060Pharmacodynamics and dosing of aminoglycosides
Q51933433Pharmacokinetic profile of once daily intravenous tobramycin in children with cystic fibrosis.
Q34297656Pharmacokinetics and pharmacodynamics of aerosolized antibacterial agents in chronically infected cystic fibrosis patients
Q36911111Pharmacokinetics and pharmacodynamics of antibacterial agents
Q37263821Pharmacokinetics and pharmacodynamics of once-daily administration of intravenous tobramycin in adult patients with cystic fibrosis hospitalized for an acute pulmonary exacerbation
Q45019997Pharmacokinetics of once and twice daily dosing of intravenous tobramycin in paediatric patients with cystic fibrosis
Q37940005Tobramycin Inhalation Powder™: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis
Q43276198Tobramycin once- vs thrice-daily for elective intravenous antipseudomonal therapy in pediatric cystic fibrosis patients
Q37608274Update on antibiotics for infection control in cystic fibrosis

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