Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants

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Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0891-5849(00)00258-6
P698PubMed publication ID10927177

P2093author name stringClemens JA
P2860cites workThe neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the ratQ72194046
Incomplete cerebral ischemia in the rat provokes increase of tissue and plasma malondialdehydeQ72308847
NF-kappaB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell typeQ77921238
The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NFKBQ23923885
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1Q24564855
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinaseQ28144326
NF-kappaB is a target of AKT in anti-apoptotic PDGF signallingQ28144330
Inflammatory mediators and stroke: new opportunities for novel therapeuticsQ33718239
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.Q33959017
N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemiaQ34286843
The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic propertiesQ35586685
Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in ratsQ36787446
Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neuronsQ38326966
NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transitionQ39445143
Immediate early gene expression in response to cerebral ischemia. Friend or foe?Q41092889
Nitrone-based free radical traps as neuroprotective agents in cerebral ischaemia and other pathologies.Q41301334
Transcription factor NF-kappaB: friend or foe of neurons?Q41716234
Differential induction of mRNA species encoding several classes of stress proteins following focal cerebral ischemia in ratsQ48089739
NF-kappaB is activated and promotes cell death in focal cerebral ischemiaQ48220270
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathwayQ48272975
The antioxidant LY231617 reduces global ischemic neuronal injury in ratsQ48290608
Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvesselsQ48292829
Inhibition of iron-dependent and ischemia-induced brain damage by the alpha-tocopherol analogue MDL 74,722.Q48299567
Free radical scavenger OPC-14117 attenuates quinolinic acid-induced NF-kappaB activation and apoptosis in rat striatumQ48305328
Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-kappaB in ratsQ48512027
Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatumQ48555071
Bcl-Xshort is elevated following severe global ischemia in rat brainsQ48557929
Global cerebral ischemia activates nuclear factor-kappa B prior to evidence of DNA fragmentationQ48617866
Global ischemia activates nuclear factor-kappa B in forebrain neurons of ratsQ48717840
Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in ratsQ48931938
Anoxic injury of endothelial cells increases production of nitric oxide and hydroxyl radicalsQ49117235
Regulatory differences in the stress response of hippocampal neurons and glial cells after heat shock.Q52203003
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damageQ70875662
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcerebral infarctionQ1209150
P304page(s)1526-1531
P577publication date2000-05-01
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleCerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants
P478volume28

Reverse relations

cites work (P2860)
Q336231323,4-oxo-isopropylidene-shikimic acid inhibits cerebral ischemia-induced oxidative stress and neuronal apoptosis in rats
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