Implication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages

scientific article

Implication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1194/JLR.M003558
P932PMC publication ID2903815
P698PubMed publication ID20332422

P2093author name stringAlexandros D Tselepis
Andromaxi A Dimitriou
Constantinos A Demopoulos
Eleni E Kotsifaki
Ewoud C van Winden
Konstantinos P Markakis
Maria K Koropouli
Stavroula Grammenou-Savvoglou
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
A simple method for the isolation and purification of total lipides from animal tissuesQ25939009
A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid)Q28283360
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol depositionQ28625661
The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoproteinQ28647592
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36Q28648010
Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptorQ28678254
Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptorsQ28678467
THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUMQ29391553
The pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Phosphorus assay in column chromatographyQ29614973
Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicityQ29617216
Role of oxidative modifications in atherosclerosisQ29617974
Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteinsQ33834184
Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo StudyQ34987055
Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolaseQ35062409
Impact of oxidized low density lipoprotein on vascular cellsQ36313378
Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosisQ36348728
Endothelial scavenger receptorsQ36483265
Scavenger receptors in atherosclerosis: beyond lipid uptakeQ36489900
CD36 and macrophages in atherosclerosisQ36795000
Lipoprotein-associated phospholipase A2: a risk marker or a risk factor?Q37189878
Lipoprotein-associated phospholipase A2: an independent predictor of coronary artery disease events in primary and secondary preventionQ37189882
Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cellsQ37207411
Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoproteinQ37686917
Lysophosphatidylcholine exhibits selective cytotoxicity, accompanied by ROS formation, in RAW 264.7 macrophagesQ39878177
Role of oxidized low density lipoprotein in atherogenesisQ40343074
The state of macrophage differentiation determines the TNFα response to nitrated lipoprotein uptakeQ40617645
Pefabloc, 4-[2-aminoethyl]benzenesulfonyl fluoride, is a new, potent nontoxic and irreversible inhibitor of PAF-degrading acetylhydrolaseQ40949634
Susceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cellsQ41382271
Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation.Q41874485
N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL.Q43759106
Rapid, fluorimetric-liquid chromatographic determination of malondialdehyde in biological samplesQ44052534
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.Q44081169
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivoQ46189376
Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitroQ47253438
Lysophosphatidylcholine induces the production of IL-1beta by human monocytesQ47987190
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteinsQ59060592
Platelet-activating factor formation during oxidative modification of low-density lipoprotein when PAF-acetylhydrolase has been inactivatedQ59394776
Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic LesionsQ59704158
Human plasma platelet-activating factor acetylhydrolase. Purification and propertiesQ68962704
An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasmaQ69182684
Hydrolysis of phosphatidylcholine during LDL oxidation is mediated by platelet-activating factor acetylhydrolaseQ69614163
Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substratesQ70169343
Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition productsQ70328162
Conjugation of apolipoprotein B with liposomes and targeting to cells in cultureQ70463750
Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidationQ70580559
The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferationQ71762941
Apolipoprotein B-bound lipids as a marker for evaluation of low density lipoprotein oxidation in vivoQ72066354
Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophagesQ72878716
Structural requirements for the binding of modified proteins to the scavenger receptor of macrophagesQ72956726
Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosisQ80229721
Lipoprotein-associated phospholipase A2 decreases oxidized lipoprotein cellular association by human macrophages and hepatocytesQ84862808
P433issue8
P304page(s)2191-2201
P577publication date2010-03-23
P1433published inJournal of Lipid ResearchQ6295449
P1476titleImplication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages
P478volume51

Reverse relations

cites work (P2860)
Q89156710A Fluorescence-Labeled Heptapeptide, (FITC)KP6, as an Efficient Probe for the Specific Detection of Oxidized and Minimally Modified Low-Density Lipoprotein
Q88474287A Method for In Vitro Measurement of Oxidized Low-Density Lipoprotein in Blood, Using Its Antibody, Fluorescence-Labeled Heptapeptide and Polyethylene Glycol
Q36686099Low-density lipoprotein, its susceptibility to oxidation and the role of lipoprotein-associated phospholipase A2 and carboxyl ester lipase lipases in atherosclerotic plaque formation

Search more.