Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity

scientific article

Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/1529-0131(200008)43:8<1663::AID-ANR1>3.0.CO;2-1
P698PubMed publication ID10943854

P2093author name stringFazzini F
Manfredi AA
Sabbadini MG
Rovere P
Rugarli C
Zimmermann VS
Bondanza A
P2860cites workThe induction of tolerance by dendritic cells that have captured apoptotic cellsQ24671078
How can cryptic epitopes trigger autoimmunity?Q24678950
Dendritic cells and the control of immunityQ27860918
Structure and function of the pentraxinsQ28302580
Rapid nucleolytic degradation of the small cytoplasmic Y RNAs during apoptosisQ28371236
Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytesQ28609747
Immunobiology of dendritic cellsQ29547465
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAFQ29615685
The role of phosphatidylserine in recognition of apoptotic cells by phagocytesQ33592283
Apoptosis: the importance of being eatenQ33592289
Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune diseaseQ33592314
The key role of nucleosomes in lupusQ33633300
The genes of systemic autoimmunityQ33650380
Developmental regulation of dendritic cell functionQ33664764
Viruses, host responses, and autoimmunityQ33713351
Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritisQ33716988
The role of apoptosis in systemic lupus erythematosus.Q33787902
Relation between infection and autoimmunity in mixed cryoglobulinemiaQ33824793
Apoptosis in human autoimmune diseasesQ33836352
CD14-dependent clearance of apoptotic cells: relevance to the immune system.Q33840497
Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.Q33855405
Natural adjuvants: endogenous activators of dendritic cellsQ33878894
Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histoneQ34255110
Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell responseQ35050844
Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupusQ36361685
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytesQ36363024
Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1Q36364968
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alphaQ36367113
Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunityQ36375304
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cellsQ36375909
Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune diseaseQ36375982
Maturation stages of mouse dendritic cells in growth factor-dependent long-term culturesQ36376739
Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigensQ36400803
CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cellsQ36400881
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cellsQ36401207
The central role of CD4(+) T cells in the antitumor immune responseQ36401381
Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destructionQ36401408
Systemic exposure to irradiated apoptotic cells induces autoantibody productionQ36401434
Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissueQ36404280
Lethal effect of the anti-Fas antibody in miceQ36696599
A review on the biological properties of C-reactive proteinQ37449779
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosusQ37722431
The origin, sequence, structure, and consequences of developing anti-DNA antibodies. A human perspectiveQ40387098
Quantitation of precipitating antibodies to certain soluble nuclear antigens in sleQ40647054
The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A proteinQ40738906
A vision of cell death: insights into immune privilegeQ40898578
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infectionQ40907799
Dendritic cell presentation of antigens from apoptotic cells in a proinflammatory context: role of opsonizing anti-beta2-glycoprotein I antibodiesQ40942556
Dendritic cells preferentially internalize apoptotic cells opsonized by anti-beta2-glycoprotein I antibodiesQ40997124
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLsQ41057373
Immunology of the antiphospholipid antibody syndromeQ41116413
Presentation of self peptides by dendritic cells: possible implications for the pathogenesis of rheumatoid arthritisQ41145666
Recent developments in the understanding of antinuclear autoantibodiesQ41258667
What triggers anti-dsDNA antibodies?Q41438979
Apoptosis in the rheumatic diseasesQ41640058
Homeostasis and self-tolerance in the immune system: turning lymphocytes off.Q41735900
Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cellsQ41834144
Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropeniaQ42025177
A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodesQ42039464
Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosusQ43779444
Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosusQ47849248
Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigensQ47849301
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunityQ56595317
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodiesQ57089602
Immunosuppressive effects of apoptotic cellsQ59060221
P433issue8
P921main subjectapoptotic processQ14599311
suicide preventionQ3298118
suicideQ10737
suicide riskQ47319077
P304page(s)1663-1672
P577publication date2000-08-01
P1433published inArthritis & RheumatologyQ4797636
P1476titleRemnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity
P478volume43

Reverse relations

cites work (P2860)
Q51052396Accumulation of plasma nucleosomes upon treatment with anti-tumour necrosis factor-alpha antibodies.
Q36272782Anti-nuclear autoantibodies: clinical utility for diagnosis, prognosis, monitoring, and planning of treatment strategy in systemic immunoinflammatory diseases
Q42964150Apoptosis and autoimmunity induced by clodronate in systemic lupus erythematosus mononuclear circulating cells.
Q36535200Apoptosis and autoimmunity: when apoptotic cells break their silence.
Q44183286Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebs
Q43627126Atorvastatin-induced dermatomyositis
Q28218204Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders
Q40650525Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis.
Q47675146Defective function of Fas in T cells from paediatric patients with autoimmune thyroid diseases.
Q36371130Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
Q36699918Dendritic cells and cytokines in human inflammatory and autoimmune diseases
Q36370588Directing autoimmunity to nucleoprotein particles: the impact of dendritic cells and interferon alpha in lupus
Q36566594Endometriosis, a disease of the macrophage
Q37575071Epigenetic histone code and autoimmunity
Q24800835Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis
Q31022558Identification of the B-cell epitopes of the early endosome antigen 1 (EEA1).
Q44250397Induction of cell death by sera from patients with acute brain injury as a mechanism of production of autoantibodies.
Q50769799Influence on spontaneous tissue inflammation by the major histocompatibility complex region in the nonobese diabetic mouse.
Q38194575Instructive influences of phagocytic clearance of dying cells on neutrophil extracellular trap generation.
Q36701020Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review
Q44876214Lupus-like syndrome associated with statin therapy
Q34106947PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation
Q84923118Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis
Q52655916Required role of apoptotic myogenic precursors and toll-like receptor stimulation for the establishment of autoimmune myositis in experimental murine models.
Q37103259Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications.
Q43800695Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity
Q33950104Structural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cells
Q64882605The Role of Efferocytosis in Autoimmune Diseases.
Q37030639The genetics and biology of Irf5-mediated signaling in lupus
Q39961855The immune reaction against allogeneic necrotic cells is reduced in Annexin A5 knock out mice whose macrophages display an anti-inflammatory phenotype.
Q34680879The neuropathology and pathogenesis of systemic lupus erythematosus
Q79788888[Autoimmune diseases and statins]
Q40728434beta-cell antigen-specific CD56(+) NKT cells from type 1 diabetic patients: autoaggressive effector T cells damage human CD56(+) beta cells by HLA-restricted and non-HLA-restricted pathways

Search more.