Regulation and isoform function of the V-ATPases

scientific article

Regulation and isoform function of the V-ATPases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1021/BI100397S
P932PMC publication ID2907102
P698PubMed publication ID20450191
P5875ResearchGate publication ID44580414

P2093author name stringMichael Forgac
Regina Saum
Masashi Toei
P2860cites workMutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafnessQ22008703
Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116-kD subunit, cause recessive distal renal tubular acidosis with preserved hearingQ24290187
Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machineryQ24298213
Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and boneQ24299288
V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathwayQ24301314
Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pumpQ24311929
The d subunit plays a central role in human vacuolar H(+)-ATPasesQ24336916
Crystal structure of yeast V-ATPase subunit C reveals its stator functionQ24537170
Role of Vma21p in assembly and transport of the yeast vacuolar ATPaseQ24562034
Structure of the yeast vacuolar ATPaseQ24645117
AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cellsQ24657352
ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cellsQ24672098
Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiaeQ27632659
Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase.Q52170550
VMA11 and VMA16 encode second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase.Q52523934
Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.Q52575042
Mouse proton pump ATPase C subunit isoforms (C2-a and C2-b) specifically expressed in kidney and lung.Q54757837
Site-directed mutagenesis of the yeast V-ATPase B subunit (Vma2p)Q70915145
Inhibition of vacuolar H(+)-ATPase by disulfide bond formation between cysteine 254 and cysteine 532 in subunit AQ72403613
Cysteine scanning mutagenesis of the noncatalytic nucleotide binding site of the yeast V-ATPaseQ73316759
ARF1 regulates pH-dependent COP functions in the early endocytic pathwayQ73538511
Determinants of the pH of the Golgi complexQ73626599
Molecular characterization of the yeast vacuolar H+-ATPase proton poreQ73821753
Mutations in the CYS4 gene provide evidence for regulation of the yeast vacuolar H+-ATPase by oxidation and reduction in vivoQ73824896
Mutational analysis of the nucleotide binding sites of the yeast vacuolar proton-translocating ATPaseQ73995925
The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cellsQ79259889
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formationQ79383955
Identification of a domain in the V0 subunit d that is critical for coupling of the yeast vacuolar proton-translocating ATPaseQ80064994
RAVE is essential for the efficient assembly of the C subunit with the vacuolar H(+)-ATPaseQ80595390
Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPaseQ27642805
Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondriaQ27730864
The first putative transmembrane segment of subunit c" (Vma16p) of the yeast V-ATPase is not necessary for functionQ27930414
Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociationQ27932441
STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1pQ27934832
Topological characterization of the c, c', and c" subunits of the vacuolar ATPase from the yeast Saccharomyces cerevisiae.Q27935602
Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assemblyQ27936413
The yeast vacuolar proton-translocating ATPase contains a subunit homologous to the Manduca sexta and bovine e subunits that is essential for functionQ27936470
The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle traffickingQ27936889
The RAVE complex is essential for stable assembly of the yeast V-ATPaseQ27937710
The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis.Q27939014
Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosisQ28140437
The amino-terminal domain of the B subunit of vacuolar H+-ATPase contains a filamentous actin binding siteQ28142113
The H subunit (Vma13p) of the yeast V-ATPase inhibits the ATPase activity of cytosolic V1 complexesQ28142904
A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit EQ28201391
Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and manQ28201425
Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosisQ28207921
Mannose 6-phosphate receptors: new twists in the taleQ28213265
The vacuolar (H+)-ATPases--nature's most versatile proton pumpsQ28218190
Mechanisms of pathogen entry through the endosomal compartmentsQ28245917
Cysteine-mediated cross-linking indicates that subunit C of the V-ATPase is in close proximity to subunits E and G of the V1 domain and subunit a of the V0 domainQ28256037
Disassembly and reassembly of the yeast vacuolar H(+)-ATPase in vivoQ28294160
Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunitsQ28505548
Differential localization of the vacuolar H+ pump with G subunit isoforms (G1 and G2) in mouse neuronsQ28511629
V-ATPase expression in the mouse olfactory epitheliumQ28512660
Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunitQ28512781
Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymisQ28566043
Alternative splicing controls neuronal expression of v-ATPase subunit a1 and sorting to nerve terminalsQ28574990
Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymisQ28581189
A novel accessory subunit for vacuolar H(+)-ATPase from chromaffin granulesQ28615855
Endocytic recyclingQ29547737
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiologyQ29614686
Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilusQ30476371
A novel role for subunit C in mediating binding of the H+-V-ATPase to the actin cytoskeletonQ31133383
Specific sorting of the a1 isoform of the V-H+ATPase a subunit to nerve terminals where it associates with both synaptic vesicles and the presynaptic plasma membraneQ44644021
The glycolytic enzyme aldolase mediates assembly, expression, and activity of vacuolar H+-ATPaseQ44691509
Three-dimensional structure of the vacuolar ATPase. Localization of subunit H by difference imaging and chemical cross-linkingQ44989683
Building the stator of the yeast vacuolar-ATPase: specific interaction between subunits E and G.Q45005907
Vacuolar-type H(+)-ATPase with the a3 isoform is the proton pump on premature melanosomesQ46647449
Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivoQ47073906
Differential expression of a subunit isoforms of the vacuolar-type proton pump ATPase in mouse endocrine tissuesQ48170696
Recombinant SFD isoforms activate vacuolar proton pumpsQ48205349
A novel mechanism for regulation of vacuolar acidificationQ48420638
Cysteine 254 of the 73-kDa A subunit is responsible for inhibition of the coated vesicle (H+)-ATPase upon modification by sulfhydryl reagentsQ48506354
Molecular characterization of the 50- and 57-kDa subunits of the bovine vacuolar proton pumpQ32105258
An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45.Q33614728
Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.Q33694769
Reversible association between the V1 and V0 domains of yeast vacuolar H+-ATPase is an unconventional glucose-induced effectQ33781665
Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinaseQ33840526
Arg-735 of the 100-kDa subunit a of the yeast V-ATPase is essential for proton translocationQ33947735
The rotary mechanism of ATP synthaseQ34103409
Renal vacuolar H+-ATPaseQ34350645
The evolution of A-, F-, and V-type ATP synthases and ATPases: reversals in function and changes in the H+/ATP coupling ratioQ34357430
The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila.Q34420273
Cysteine cathepsins and the cutting edge of cancer invasionQ34605340
The V-type H+ ATPase: molecular structure and function, physiological roles and regulationQ34651704
Evidence for rotation of V1-ATPase.Q34804967
A journey from mammals to yeast with vacuolar H+-ATPase (V-ATPase).Q35592066
The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegansQ36117665
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPaseQ36416690
Tissue specific expression of the splice variants of the mouse vacuolar proton-translocating ATPase a4 subunitQ36542515
Arrangement of subunits in the proteolipid ring of the V-ATPaseQ36670673
Cellular environment is important in controlling V-ATPase dissociation and its dependence on activityQ36672123
Characterization of the osteoclast vacuolar H+-ATPase B-subunitQ36690409
Subunit H of the vacuolar (H+) ATPase inhibits ATP hydrolysis by the free V1 domain by interaction with the rotary subunit F.Q36690941
Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase RecyclingQ36838890
Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cellsQ37269119
Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle traffickingQ37485524
Site-directed mutagenesis of the yeast V-ATPase A subunitQ38346161
Mutational analysis of the non-homologous region of subunit A of the yeast V-ATPaseQ38357981
Selective expression of vacuolar H+-ATPase subunit d2 by particular subsets of dendritic cells among leukocytesQ40376754
Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activityQ40592797
From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiationQ40658848
Structure of the vacuolar ATPase by electron microscopyQ41699446
The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeastQ41829576
Involvement of the nonhomologous region of subunit A of the yeast V-ATPase in coupling and in vivo dissociationQ41913510
Stimulus-induced phosphorylation of vacuolar H(+)-ATPase by protein kinase A.Q42031982
The V-ATPase subunit C binds to polymeric F-actin as well as to monomeric G-actin and induces cross-linking of actin filamentsQ42043242
Subunit interactions and requirements for inhibition of the yeast V1-ATPaseQ43131524
Microtubules are involved in glucose-dependent dissociation of the yeast vacuolar [H+]-ATPase in vivoQ43594127
Localization of subunits D, E, and G in the yeast V-ATPase complex using cysteine-mediated cross-linking to subunit B.Q44130595
Activation of lysosomal function during dendritic cell maturationQ44333919
Subunit rotation of vacuolar-type proton pumping ATPase: relative rotation of the G and C subunitsQ44387465
Expression and function of the mouse V-ATPase d subunit isoformsQ44578323
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)4715-4723
P577publication date2010-06-01
P1433published inBiochemistryQ764876
P1476titleRegulation and isoform function of the V-ATPases
P478volume49

Reverse relations

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