Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks

scientific article

Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks is …
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scholarly articleQ13442814

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P356DOI10.1128/IAI.68.8.4759-4764.2000
P932PMC publication ID98430
P698PubMed publication ID10899883

P2093author name stringX Yang
M V Norgard
J D Radolf
S K Wikel
M J Caimano
G B Schoeler
K E Hagman
P2860cites workInduction of an outer surface protein on Borrelia burgdorferi during tick feedingQ24564198
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Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory miceQ32063128
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosisQ32063131
Tick modulation of host immunity: an important factor in pathogen transmissionQ33730089
Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infectionQ33753858
DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodiesQ33767776
Access of antibody or trypsin to an integral outer membrane protein (P66) of Borrelia burgdorferi is hindered by Osp lipoproteins.Q34001101
Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferiQ35452406
Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccineQ36366055
Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized miceQ37058962
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Adherence of Borrelia burgdorferi. Identification of critical lysine residues in DbpA required for decorin bindingQ38320948
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Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi.Q40267193
Sequence variation in the outer-surface-protein genes of Borrelia burgdorferiQ43865595
A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study ConsortiumQ47625328
Immunization against Lyme disease--an important first stepQ47805634
Decorin-binding adhesins from Borrelia burgdorferiQ47977071
Isolation of antigenic components from the Lyme disease spirochete: their role in early diagnosisQ69755062
Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feedingQ71553676
Characterization of the protective borreliacidal antibody response in humans and hamsters after vaccination with a Borrelia burgdorferi outer surface protein A vaccineQ71618821
Transcriptional and translational regulation of the expression of the major outer surface proteins in Lyme disease Borrelia strainsQ71709765
Genetic heterogeneity of Borrelia burgdorferi in the United StatesQ71949255
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectimmunizationQ1415366
Borrelia burgdorferiQ2723634
tick infestationQ4199106
P304page(s)4759-4764
P577publication date2000-08-01
P1433published inInfection and ImmunityQ6029193
P1476titleDecorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks
P478volume68

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