Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes

scientific article

Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1039/C003079C
P932PMC publication ID2909375
P698PubMed publication ID20485834
P5875ResearchGate publication ID44614538

P50authorStephen J. LippardQ557509
P2093author name stringErwin Reisner
Simone Friedle
P2860cites workCrystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methaneQ22061875
The Leeuwenhoek Lecture 2000 the natural and unnatural history of methane-oxidizing bacteriaQ24676964
The catalytic pathway of cytochrome p450cam at atomic resolutionQ27621595
Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylaseQ27631133
X-ray Structure of a Hydroxylase−Regulatory Protein Complex from a Hydrocarbon-Oxidizing Multicomponent Monooxygenase, Pseudomonas sp. OX1 Phenol Hydroxylase † , ‡Q27640833
myo-Inositol oxygenase: a radical new pathway for O(2) and C-H activation at a nonheme diiron clusterQ28307759
Water induces a structural conversion and accelerates the oxygenation of carboxylate-bridged non-heme diiron enzyme synthetic analoguesQ31050604
Synthesis of diethynyltriptycene-linked dipyridyl ligandsQ33224734
Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathwayQ33554957
Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteinsQ33615672
Dendritic Encapsulation of Function: Applying Nature's Site Isolation Principle from Biomimetics to Materials ScienceQ33932656
Intermediates in the oxygenation of a nonheme diiron(II) complex, including the first evidence for a bound superoxo speciesQ33936596
Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins A list of abbreviations can be found in Section 7.Q34334373
Methanotrophic bacteriaQ34396674
Iron substitution for sodium in a carboxylate-bridged, heterodinuclear sodium-iron complexQ34455294
High-valent iron(IV)-oxo complexes of heme and non-heme ligands in oxygenation reactionsQ34624196
Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?Q35150156
Synthetic models for non-heme carboxylate-bridged diiron metalloproteins: strategies and tactics.Q35660899
Stalking intermediates in oxygen activation by iron enzymes: motivation and methodQ36411958
Synthesis and Characterization of a Ditriflate-Bridged, Diiron(II) Complex with Syn-N-Donor Ligands: [Fe(2)(μ-OTf)(2)(PIC(2)DET)(2)](BARF)(2)Q36632305
Iron complexes of dendrimer-appended carboxylates for activating dioxygen and oxidizing hydrocarbonsQ36676776
A synthetic precedent for the [FeIV2(mu-O)2] diamond core proposed for methane monooxygenase intermediate Q.Q36693083
The biochemistry of methane oxidationQ36747482
Dioxygen-initiated oxidation of heteroatomic substrates incorporated into ancillary pyridine ligands of carboxylate-rich diiron(II) complexesQ36826014
Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexesQ36826066
Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases.Q36828707
Finding intermediates in the O2 activation pathways of non-heme iron oxygenases.Q36848901
Mechanistic studies of the oxidative N-dealkylation of a substrate tethered to carboxylate-bridged diiron(II) complexes, [Fe2(mu-O2CAr(Tol))2(O2CAr(Tol))2(N,N-Bn2en)2]Q36983347
9-Triptycenecarboxylate-Bridged Diiron(II) Complexes: Capture of the Paddlewheel Geometric IsomerQ37029926
Desaturases: emerging models for understanding functional diversification of diiron-containing enzymesQ37254049
Biologically inspired oxidation catalysisQ37272551
Spectroscopic and computational studies of (mu-oxo)(mu-1,2-peroxo)diiron(III) complexes of relevance to nonheme diiron oxygenase intermediatesQ37329310
Human deoxyhypusine hydroxylase, an enzyme involved in regulating cell growth, activates O2 with a nonheme diiron centerQ37329690
A diiron(IV) complex that cleaves strong C-H and O-H bondsQ37347607
Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV.Q37380042
Low-molecular-weight analogues of the soluble methane monooxygenase (sMMO): from the structural mimicking of resting states and intermediates to functional modelsQ37603215
Characterization of the arene-oxidizing intermediate in ToMOH as a diiron(III) speciesQ41280148
Synthesis and reactivity of Haloacetato derivatives of iron(II) including the crystal and the molecular structure of [Fe(CF3COOH)2(micro-CF3COO)2]nQ42163540
Oxidative N-dealkylation of a carboxylate-bridged diiron(II) precursor complex by reaction with O2 affords the elusive [Fe2(mu-OH)2(mu-O2CR)](3+) core of soluble methane monooxygenase hydroxylaseQ43678005
Functional mimic of dioxygen-activating centers in non-heme diiron enzymes: mechanistic implications of paramagnetic intermediates in the reactions between diiron(II) complexes and dioxygenQ43953534
Modeling dioxygen-activating centers in non-heme diiron enzymes: carboxylate shifts in diiron(II) complexes supported by sterically hindered carboxylate ligandsQ43989610
Iron complexes capped with dendrimer-appended triazacyclononanes as the novel spatially encumbered models of non-heme iron proteinsQ44001825
Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligandQ44700153
Crystal structure of the toluene/o-xylene monooxygenase hydroxylase from Pseudomonas stutzeri OX1. Insight into the substrate specificity, substrate channeling, and active site tuning of multicomponent monooxygenasesQ44851116
Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethersQ46494692
Water affects the stereochemistry and dioxygen reactivity of carboxylate-rich diiron(II) models for the diiron centers in dioxygen-dependent non-heme enzymesQ46532496
A planar carboxylate-rich tetraironII complex and its conversion to linear triironII and paddlewheel diironII complexesQ46903838
Synthesis and oxidation of carboxylate-bridged diiron(II) complexes with substrates tethered to primary alkyl amine ligandsQ46913254
Influence of steric hindrance on the core geometry and sulfoxidation chemistry of carboxylate-rich diiron(II) complexesQ46921854
A Bulky Benzoate Ligand for Modeling the Carboxylate-Rich Active Sites of Non-Heme Diiron EnzymesQ50021331
Catalytically active mu-Oxodiiron(IV) oxidants from Iron(III) and dioxygen.Q50777288
An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane MonooxygenaseQ57943668
Gating Effects of Component B on Oxygen Activation by the Methane Monooxygenase Hydroxylase ComponentQ57943718
Transient intermediates of the methane monooxygenase catalytic cycleQ70500721
Protein Radicals in Enzyme CatalysisQ77646639
Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate QQ78612573
Unusual peroxo intermediates in the reaction of dioxygen with carboxylate-bridged diiron(II,II) paddlewheel complexesQ78688041
Molecular recognition in the selective oxygenation of saturated C-H bonds by a dimanganese catalystQ79816001
Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteinsQ80104210
Structural and spectroscopic characterization of (mu-hydroxo or mu-oxo)(mu-peroxo)diiron(III) complexes: models for peroxo intermediates of non-heme diiron proteinsQ81288305
Ferritins: dynamic management of biological iron and oxygen chemistryQ81519808
Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three ProteinsQ88522005
P433issue8
P921main subjectbiomimeticsQ1145644
P304page(s)2768-2779
P577publication date2010-05-20
P1433published inChemical Society ReviewsQ2962268
P1476titleCurrent challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes
P478volume39

Reverse relations

cites work (P2860)
Q36162558A C2-symmetric, basic Fe(III) carboxylate complex derived from a novel triptycene-based chelating carboxylate ligand
Q62679056A Discrete μ4-Oxido Tetranuclear Iron(III) Cluster
Q51698191A Hafnium-Based Metal-Organic Framework as a Nature-Inspired Tandem Reaction Catalyst.
Q36482216A Mononuclear Carboxylate-Rich Oxoiron(IV) Complex: a Structural and Functional Mimic of TauD Intermediate 'J'
Q33855511A high-valent heterobimetallic [Cu(III)(μ-O)2Ni(III)]2+ core with nucleophilic oxo groups
Q53636451A porous coordination polymer with a reactive diiron paddlewheel unit.
Q52889913A trispyrazolylborato iron cysteinato complex as a functional model for the cysteine dioxygenase.
Q53364601A water-soluble glucose-functionalized cobalt(III) complex as an efficient electrocatalyst for hydrogen evolution under neutral conditions.
Q85511305An N-bridged high-valent diiron-oxo species on a porphyrin platform that can oxidize methane
Q53231423An abiotic analogue of the diiron(IV)oxo "diamond core" of soluble methane monooxygenase generated by direct activation of O2 in aqueous Fe(II)/EDTA solutions: thermodynamics and electronic structure.
Q38210222Applications of density functional theory to iron-containing molecules of bioinorganic interest
Q45982459Arene non-innocence in dinuclear complexes of Fe, Co, and Ni supported by a para-terphenyl diphosphine.
Q46735638C-H Activation of Benzene by a Photoactivated Ni(II)(azide): Formation of a Transient Nickel Nitrido Complex
Q28078677Carbon Nanodots as Peroxidase Nanozymes for Biosensing
Q50221995Catalytic Fehling's Reaction: An Efficient Aerobic Oxidation of Aldehyde Catalyzed by Copper in Water
Q54342839Chemistry with methane: concepts rather than recipes.
Q48264488Classical hydrogen bonding and stacking of chelate rings in new copper(ii) complexes.
Q37714484Conversion Between Doubly and Triply Carboxylate-Bridged Di(ethylzinc) Complexes and Formation of the (μ-Oxo)tetrazinc Carboxylate [Zn4O(Ar(Tol)CO2)6].
Q37520342Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n-1 aldehydes and alcohols in addition to alkanes
Q38876136Design and engineering of artificial oxygen-activating metalloenzymes
Q35250210Design and synthesis of a novel triptycene-based ligand for modeling carboxylate-bridged diiron enzyme active sites
Q45374562Design, synthesis and characterization of a hexapeptide bio-inspired by acetylcholinesterase and its interaction with pesticide dichlorvos
Q36379522Diiron centre mutations in Ciona intestinalis alternative oxidase abolish enzymatic activity and prevent rescue of cytochrome oxidase deficiency in flies
Q92156446Diiron oxo reactivity in a weak-field environment
Q46532319Diiron(III)-μ-Fluoro Bisporphyrins: Effect of Bridging Ligand on the Metal Spin State
Q30650652Dinuclear complexes of copper and zinc with m-xylene/cyclohexane-linked bis-aspartic acids: synthesis, characterization, dioxygen activation, and catalytic oxidation of nitrobenzene in pure aqueous solution.
Q34819410Dioxygen activation in soluble methane monooxygenase
Q46936933Does a higher metal oxidation state necessarily imply higher reactivity toward H-atom transfer? A computational study of C-H bond oxidation by high-valent iron-oxo and -nitrido complexes.
Q52957303Effect of Inter-Porphyrin Distance on Spin-State in Diiron(III) μ-Hydroxo Bisporphyrins.
Q30698647Effect of heme-heme interactions and modulation of metal spins by counter anions in a series of diiron(III)-μ-hydroxo bisporphyrins: unusual stabilization of two different spins in a single molecular framework.
Q45931676Effect of sequestering intrinsic iron on the electron paramagnetic resonance signals in powdered soy proteins.
Q45775954Efficient oxidation of methane to methanol by dioxygen mediated by tricopper clusters
Q57835135Ein Trispyrazolylborato-Eisen-Cysteinato-Komplex als funktionelles Modell für die Cystein-Dioxygenase
Q35782860Evaluating the identity and diiron core transformations of a (μ-oxo)diiron(III) complex supported by electron-rich tris(pyridyl-2-methyl)amine ligands
Q27028195Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites
Q42314601Exploring secondary-sphere interactions in Fe-N x H y complexes relevant to N2 fixation
Q34778885Ferritin protein nanocages use ion channels, catalytic sites, and nucleation channels to manage iron/oxygen chemistry
Q46580925Formation and High Reactivity of the anti-Dioxo Form of High-Spin μ-Oxodioxodiiron(IV) as the Active Species That Cleaves Strong C-H Bonds.
Q38561781Graphene-Based Nanomaterials as Efficient Peroxidase Mimetic Catalysts for Biosensing Applications: An Overview.
Q57818442Half-of-the-Sites Reactivity of the Castor Δ9-18:0-Acyl Carrier Protein Desaturase
Q47404723High-Energy-Resolution Fluorescence-Detected X-ray Absorption of the Q Intermediate of Soluble Methane Monooxygenase.
Q58607260High-Resolution EXAFS Provides Evidence for a Longer Fe•••Fe Distance in the Q Intermediate of Methane Monooxygenase
Q50042283Hydrogen-Atom Transfer Oxidation with H2O2 Catalyzed by [FeII(1,2-bis(2,2'-bipyridyl-6-yl)ethane(H2O)2]2+: Likely Involvement of a (μ-Hydroxo)(μ-1,2-peroxo)diiron(III) Intermediate.
Q52764477Hydroxo-bridged diiron(iii) and dimanganese(iii) bisporphyrins: modulation of metal spins by counter anions.
Q59287898Iron-Catalyzed CH Hydroxylation and Olefincis-Dihydroxylation Using a Single-Electron Oxidant and Water as the Oxygen-Atom Source
Q57833954Metal Substitution and Solvomorphism in Alkylthiolate-Bridged Zn3 and HgZn2 Metal Clusters
Q38845297Mono- and binuclear non-heme iron chemistry from a theoretical perspective
Q34348960Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Q53298873Novel iminopyridine derivatives: ligands for preparation of Fe(ii) and Cu(ii) dinuclear complexes.
Q45758883Photoassisted generation of a dinuclear iron(III) peroxo species and oxygen-atom transfer.
Q38189609Recent advances in heterogeneous selective oxidation catalysis for sustainable chemistry.
Q46738697Redox-inactive metal ions promoted the catalytic reactivity of non-heme manganese complexes towards oxygen atom transfer
Q52872635Remarkable Anion-Dependent Spin-State Switching in Diiron(III) μ-Hydroxo Bisporphyrins: What Role do Counterions Play?
Q60435728Role of copper and iron in methane oxidation and bacterial biopolymer accumulation
Q58227373Roles of carboxylate donors in O–O bond scission of peroxodi-iron(iii) to high-spin oxodi-iron(iv) with a new carboxylate-containing dinucleating ligand
Q52868282Structure and mechanism leading to formation of the cysteine sulfinate product complex of a biomimetic cysteine dioxygenase model.
Q45996276Surfactant-Assisted Phase-Selective Synthesis of New Cobalt MOFs and Their Efficient Electrocatalytic Hydrogen Evolution Reaction.
Q90978393Synthesis and Binding Properties of a Tren-Capped Hexahomotrioxacalix[3]arene
Q38141075The alternative oxidases: simple oxidoreductase proteins with complex functions.
Q37991179The biology and chemistry of high-valent iron-oxo and iron-nitrido complexes
Q38831956The past, present, and future of the Yang reaction
Q35146486Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework
Q34043233Transition metal complexes and the activation of dioxygen
Q36761857Triptycene-based Bis(benzimidazole) Carboxylate-Bridged Biomimetic Diiron(II) Complexes
Q53340455Unexpected weak magnetic exchange coupling between haem and non-haem iron in the catalytic site of nitric oxide reductase (NorBC) from Paracoccus denitrificans1.
Q37560318Versatile reactivity of a solvent-coordinated diiron(II) compound: synthesis and dioxygen reactivity of a mixed-valent Fe(II)Fe(III) species
Q59287904Well-Defined Heterometallic and Unsymmetric M2O2 Complexes Arising from Binding and Activation of O2

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