Expression of miR-34c induces G2/M cell cycle arrest in breast cancer cells

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Expression of miR-34c induces G2/M cell cycle arrest in breast cancer cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1025293320
P356DOI10.1186/1471-2407-14-538
P932PMC publication ID4125691
P698PubMed publication ID25064703
P5875ResearchGate publication ID264314842

P2093author name stringChrister Larsson
Yvonne Ceder
Chandrani Achari
Sofia Winslow
P2860cites workmiRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancerQ21133750
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cellsQ24329077
MicroRNAs: target recognition and regulatory functionsQ24609584
miR-34a repression of SIRT1 regulates apoptosisQ24652720
A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor geneQ39978280
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrestQ39992760
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.Q40102003
Evidence linking CD44-positive cells and gemcitabine resistance in pancreatic cancer cells: need for further substantiationQ43251963
Deletion of chromosome 11p15, p12, q22, q23-24 loci in human prostate cancerQ46250990
Chromosomal alterations associated with the transition from in situ to invasive breast cancerQ46486645
Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3.Q46714700
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrestQ48078984
Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis.Q53259995
Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regionsQ72033722
Identification of a 6-cM minimal deletion at 11q23.1-23.2 and exclusion of PPP2R1B gene as a deletion target in cervical cancerQ73299575
MicroRNAs in cancerQ86065522
miR-34c is downregulated in prostate cancer and exerts tumor suppressive functionsQ95780206
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosisQ24798477
MicroRNA targets in DrosophilaQ24806738
Combinatorial microRNA target predictionsQ27860510
Mammalian microRNAs predominantly act to decrease target mRNA levelsQ27860535
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
The diverse functions of microRNAs in animal development and diseaseQ28266193
MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cellsQ28287986
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancerQ28291502
A microRNA component of the p53 tumour suppressor networkQ28305330
Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signalingQ28477912
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replicationQ28587920
microRNA-34a promotes DNA damage and mitotic catastrophe.Q30409530
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenesQ30434616
miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiformeQ33856653
PKCalpha expression is a marker for breast cancer aggressivenessQ33864132
miRWalk--database: prediction of possible miRNA binding sites by "walking" the genes of three genomesQ34186822
MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotypeQ34212221
MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1.Q34221689
MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesisQ34278292
miR-34 - a microRNA replacement therapy is headed to the clinicQ34640230
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.Q34783833
MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung CancerQ34785711
MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cellsQ35643732
miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells.Q35889599
Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.Q36297343
A microRNA DNA methylation signature for human cancer metastasisQ36861111
The quest for the 1p36 tumor suppressorQ37138877
DIANA-microT web server: elucidating microRNA functions through target predictionQ37245804
1p36 tumor suppression--a matter of dosage?Q38061568
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growthQ38298486
The tumour suppressor miR-34c targets MET in prostate cancer cellsQ39114252
MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1.Q39273521
MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1.Q39343253
MicroRNAs impair MET-mediated invasive growthQ39906019
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
P304page(s)538
P577publication date2014-07-26
P1433published inBMC CancerQ326300
P1476titleExpression of miR-34c induces G2/M cell cycle arrest in breast cancer cells
P478volume14

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cites work (P2860)
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