review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1182/BLOOD-2009-09-242875 |
P8608 | Fatcat ID | release_wo3fdzd5irgbtckouvzgg23lva |
P932 | PMC publication ID | 2910605 |
P698 | PubMed publication ID | 20233971 |
P5875 | ResearchGate publication ID | 42109047 |
P2093 | author name string | Feng-Chun Yang | |
D Wade Clapp | |||
Karl Staser | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells | Q24322602 | ||
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins | Q24324729 | ||
The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene | Q24605122 | ||
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow | Q24645717 | ||
Inflammation and cancer | Q24649640 | ||
Tumor microenvironment and neurofibromatosis type I: connecting the GAPs | Q24654681 | ||
The GTPase superfamily: conserved structure and molecular mechanism | Q27860524 | ||
NF1 tumor suppressor gene function: narrowing the GAP | Q28203741 | ||
Mast cells are an essential hematopoietic component for polyp development | Q36288986 | ||
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines | Q36400929 | ||
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells | Q37001981 | ||
Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation. | Q37253335 | ||
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas | Q37332217 | ||
Translation of the Philadelphia chromosome into therapy for CML. | Q37344094 | ||
Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation | Q37383632 | ||
The cellular functions of small GTP-binding proteins | Q37821945 | ||
Von Recklinghausen neurofibromatosis | Q40262766 | ||
The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others. | Q40486326 | ||
The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. | Q40821493 | ||
Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells | Q40842515 | ||
The neurofibromatosis type 1 gene and its protein product, neurofibromin. | Q40890889 | ||
Role for the stem cell factor/KIT complex in Schwann cell neoplasia and mast cell proliferation associated with neurofibromatosis | Q41487729 | ||
Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway | Q42538041 | ||
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis | Q42806305 | ||
Inflammatory cells and cancer: think different! | Q42944409 | ||
Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function | Q44189816 | ||
Neurofibromatosis: past, present, and future | Q45012916 | ||
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells | Q46486969 | ||
Analysis of vascularity of human neurofibromas | Q47957444 | ||
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. | Q48106714 | ||
Analysis of the neurofibromatosis type 1 (NF1) GAP-related domain by site-directed mutagenesis. | Q52517404 | ||
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. | Q52584140 | ||
Neurofibromatosis and cancer. | Q53539963 | ||
Neurofibromatosis type 1 | Q57868109 | ||
The Dominant W 42 Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase | Q67653010 | ||
Mast-cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis | Q69032163 | ||
Cutaneous manifestation of neurofibromatosis: cellular interaction, pigmentation, and mast cells | Q71594074 | ||
Possible involvement of c-kit receptor and its ligand in increase of mast cells in neurofibroma tissues | Q72100660 | ||
K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells | Q79718064 | ||
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues | Q28238680 | ||
The neurofibromatosis type 1 gene encodes a protein related to GAP | Q28301160 | ||
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition | Q28301955 | ||
The GTPase superfamily: a conserved switch for diverse cell functions | Q28302983 | ||
The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus | Q28365597 | ||
Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells | Q28504730 | ||
Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia | Q28505914 | ||
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain | Q28506943 | ||
Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes | Q28506980 | ||
Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells | Q28508149 | ||
The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice | Q28511045 | ||
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus | Q28512134 | ||
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo | Q28585229 | ||
Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells | Q28586410 | ||
Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase | Q28588037 | ||
Mouse models of tumor development in neurofibromatosis type 1 | Q28591083 | ||
Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling | Q28592228 | ||
Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro | Q28594862 | ||
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 | Q28594951 | ||
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21 | Q28609120 | ||
The role of myeloid cells in the promotion of tumour angiogenesis | Q29614299 | ||
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer | Q29618155 | ||
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells | Q33757962 | ||
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W | Q33920173 | ||
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients | Q34166560 | ||
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells | Q34265808 | ||
The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus | Q34407347 | ||
Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. | Q34441257 | ||
Neurofibromas in NF1: Schwann cell origin and role of tumor environment | Q34509108 | ||
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor | Q34567286 | ||
Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures | Q34577394 | ||
Neurofibromin regulation of ERK signaling modulates GABA release and learning | Q34872465 | ||
Physical mapping of the von Recklinghausen neurofibromatosis region on chromosome 17. | Q35185266 | ||
Signal transduction through small GTPases—A tale of two GAPs | Q35228011 | ||
Mast cell modulation of tumour cell proliferation in rat mammary adenocarcinoma 13762NF | Q35984781 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mast cell | Q191989 |
P304 | page(s) | 157-164 | |
P577 | publication date | 2010-03-16 | |
P1433 | published in | Blood | Q885070 |
P1476 | title | Mast cells and the neurofibroma microenvironment | |
P478 | volume | 116 |