Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments

scientific article

Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1586/ERN.11.68
P698PubMed publication ID21539437
P5875ResearchGate publication ID51095338

P2093author name stringRandolph B Schiffer
Ariel Miller
Hillel Pratt
P2860cites workA self report measure of affective labilityQ24680227
The neuropsychiatry of pathologic affect: an approach to evaluation and treatmentQ28211021
Pathological laughter and crying: a link to the cerebellumQ28214416
A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorderQ28240047
Fluoxetine improves emotional incontinenceQ28244067
The neuropsychiatry of the cerebellum - insights from the clinicQ28245215
Citalopram for post-stroke pathological cryingQ28249344
Prevalence and neurobehavioral correlates of pathological laughing and crying in multiple sclerosisQ28249819
Pathologic laughter and crying in ALS: a search for their originQ28280249
Pathological laughter and crying in patients with closed traumatic brain injuryQ28291902
Fluoxetine as a treatment for post-stroke emotionalismQ28293082
Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar AffectQ28293218
Treatment of pathologic laughing and weeping with amitriptylineQ28306247
Pathologic laughter after unilateral stroke.Q51104089
Characteristics of responses of Golgi cells and mossy fibers to eye saccades and saccadic adaptation recorded from the posterior vermis of the cerebellum.Q51942995
The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunitiesQ55922778
Sertraline in stroke-associated lability of moodQ29031119
Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integrationQ30457456
Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processingQ30474917
Cerebellar tumour presenting with pathological laughter and gelastic syncopeQ33155393
Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatmentQ33186724
The primate cortico-cerebellar system: anatomy and functionQ33342809
Prevalence and clinical correlates of pathological affective display in Alzheimer's diseaseQ33734418
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trialQ34361996
The cerebellar cognitive affective syndromeQ34467220
Review of pseudobulbar affect including a novel and potential therapyQ34563839
Psychological associations with emotionalism after strokeQ36319120
Involuntary emotional expression disorder (IEED) in Parkinson's diseaseQ36473096
Pathological laughter and crying in patients with multiple system atrophy-cerebellar typeQ36732313
Therapeutic use of dextromethorphan: key learnings from treatment of pseudobulbar affectQ36791392
Pathological laughing and crying : epidemiology, pathophysiology and treatmentQ37188990
An investigation of the psychiatric aspects of disseminated sclerosisQ37198581
The cerebellar microcircuit as an adaptive filter: experimental and computational evidenceQ37649491
Dextromethorphan and quinidine in adult patients with uncontrolled painful diabetic peripheral neuropathy: a 29-day, multicenter, open-label, dose-escalation studyQ39342534
Duloxetine for pathological laughing and cryingQ43270208
Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affectQ43278236
Pharmacokinetics of dextromethorphan after single or multiple dosing in combination with quinidine in extensive and poor metabolizersQ45040972
Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampusQ45119878
Stimulus-induced pathologic laughter due to basilar artery dissectionQ46572900
Mirtazapine treatment for pathological laughing and crying after strokeQ46766267
Fluoxetine treatment in poststroke depression, emotional incontinence, and anger proneness: a double-blind, placebo-controlled studyQ46818777
Pathoanatomic correlation between poststroke pathological crying and damage to brain areas involved in serotonergic neurotransmissionQ48136262
Serotonin responsive and nonresponsive diurnal depressive mood disorders and pathological affect in thalamic infarct associated with myoclonus and blepharospasmQ48149765
Different responses of rat cerebellar Purkinje cells and Golgi cells evoked by widespread convergent sensory inputsQ48533222
Pontine infarction due to basilar artery stenosis presenting as pathological laughterQ48779568
Pseudobulbar affect: prevalence and quality of life impact in movement disorders.Q48840479
Inappropriate crying and laughing in Parkinson disease and movement disordersQ49109094
Exaggerated crying and tremor with a cerebellar cystQ50276898
Frequency and correlates of involuntary emotional expression disorder in Parkinson's disease.Q50716983
Brain responses to verbal stimuli among multiple sclerosis patients with pseudobulbar affect.Q50790366
Management of pathologic laughter and crying in patients with locked-in syndrome: a report of 4 cases.Q50797828
Neuroanatomy of pseudobulbar affect : a quantitative MRI study in multiple sclerosis.Q50802793
Pathological laughter as an unusual manifestation of acute stroke.Q50884709
Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis.Q50940024
Pathological laughing and crying following traumatic brain injury.Q50983203
Validation of the CNS emotional lability scale for pseudobulbar affect (pathological laughing and crying) in multiple sclerosis patients.Q50984760
Paroxetine versus citalopram treatment of pathological crying after brain injury.Q51084469
P433issue7
P921main subjectpseudobulbar affectQ3508789
P304page(s)1077-1088
P577publication date2011-05-03
P1433published inExpert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disordersQ15760319
P1476titlePseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments
P478volume11

Reverse relations

cites work (P2860)
Q48249409A frontal syndrome due to a brainstem lesion
Q55281746Alleviation of Psychological Distress and the Improvement of Quality of Life in Patients With Amyotrophic Lateral Sclerosis: Adaptation of a Short-Term Psychotherapeutic Intervention.
Q46163587Altered resting-state functional activity in isolated pontine infarction patients with pathological laughing and crying
Q38401900An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results
Q52595291Correlation between cognitive impairment during the acute phase of first cerebral infarction and development of long-term pseudobulbar affect.
Q38219309Crying and suicidal, but not depressed. Pseudobulbar affect in multiple sclerosis successfully treated with valproic acid: Case report and literature review
Q47371943Dextromethorphan-quinidine-responsive pseudobulbar affect (PBA): psychopharmacological model for wide-ranging disorders of emotional expression?
Q38270903Dextromethorphan/quinidine: a review of its use in adults with pseudobulbar affect
Q35943735Effective use of sertraline for pathological laughing after severe vasospasm due to aneurysmal subarachnoid hemorrhage: case report
Q33838839Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect
Q47840786Hashimoto's encephalopathy presenting as pseudobulbar palsy
Q53659704Is firstly diagnosed ALS really ALS? Results of a population-based study with long-term follow-up.
Q38676032Neuronal Dysregulation in Stroke-Associated Pseudobulbar Affect (PBA): Diagnostic Scales and Current Treatment Options
Q45037116Neuropsychological assessment in a case of adult-onset hemophagocytic lymphohistiocytosis (HLH).
Q53279150No tears in heaven: did the media create the pseudo-phenomenon "altitude-adjusted lachrymosity syndrome (AALS)"?
Q42176159Nonmedical treatment of patients with dementia.
Q21132546PRISM: a novel research tool to assess the prevalence of pseudobulbar affect symptoms across neurological conditions
Q64065356Pathological Crying and Laughing in Motor Neuron Disease: Pathobiology, Screening, Intervention
Q30389441Pathological laughing and crying in amyotrophic lateral sclerosis is related to frontal cortex function
Q35196901Persistent pseudobulbar affect secondary to acute disseminated encephalomyelitis
Q50589123Physical Examination for the Academic Psychiatrist: Primer and Common Clinical Scenarios.
Q37561654Prevalence of pseudobulbar affect symptoms and clinical correlates in nursing home residents
Q61806263Pseudobulbar Affect in Parkinsonian Disorders: A Review
Q34658447Pseudobulbar affect: prevalence and management
Q27315829Pseudobulbar laughter as a levodopa off phenomenon exacerbated by subthalamic deep brain stimulation
Q39065476Recognizing and treating pseudobulbar affect
Q30634431Review of Dextromethorphan 20 mg/Quinidine 10 mg (NUEDEXTA(®)) for Pseudobulbar Affect
Q58125489Revisiting the pathoanatomy of pseudobulbar affect: mechanisms beyond corticobulbar dysfunction
Q42674268Selective TNF inhibition for chronic stroke and traumatic brain injury: an observational study involving 629 consecutive patients treated with perispinal etanercept
Q92489497The epidemiology and pathophysiology of pseudobulbar affect and its association with neurodegeneration
Q28709470The human frontal lobes and frontal network systems: an evolutionary, clinical, and treatment perspective
Q52311490The neurobiology of human crying.
Q40911853Traumatic axonal injury and persistent emotional lability in an adolescent following moderate traumatic brain injury: A case study.

Search more.