Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine

scientific article

Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/2050-6511-15-42
P932PMC publication ID4130124
P698PubMed publication ID25086653
P5875ResearchGate publication ID264430449

P50authorAlison H HarrillQ62484393
P2093author name stringPaul B Watkins
Rohit Singhal
Zaid Jayyosi
Alison H Harrill
Hadj Benzerdjeb
Francoise Menguy-Vacheron
P2860cites workRelease of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicityQ34024427
Enhanced elimination of warfarin during treatment with cholestyramineQ34516501
Review article: pruritus in cholestatic and other liver diseasesQ35091959
Apoptosis: a mechanism of acute and chronic liver injuryQ36160716
Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospitalQ37346819
Drug safety sciences and the bottleneck in drug developmentQ37877129
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HMGB1: a multifunctional alarmin driving autoimmune and inflammatory diseaseQ37980335
Alanine aminotransferase: a clinical and regulatory tool for detecting liver injury-past, present, and futureQ38032729
Glutamate dehydrogenase: biochemical and clinical aspects of an interesting enzymeQ39647844
HMGB1 is an endogenous immune adjuvant released by necrotic cellsQ40104101
The role of clinical chemistry in chemical and drug safety evaluation by use of laboratory animalsQ40460980
Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR).Q41875540
Role of bile acids in liver injury and regeneration following acetaminophen overdoseQ42119327
The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers.Q43137450
High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivoQ43270651
Plasma MicroRNAs as sensitive and specific biomarkers of tissue injuryQ43278313
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Progressive stages of mitochondrial destruction caused by cell toxic bile salts.Q50983477
Serum Glutamate Dehydrogenase—Biomarker for Liver Cell Death or Mitochondrial Dysfunction?Q57724784
Circulating microRNAs as potential markers of human drug-induced liver injuryQ60609564
A multicenter comparison of lovastatin and cholestyramine therapy for severe primary hypercholesterolemia. The Lovastatin Study Group IIIQ69919273
Comparative efficacy and safety of pravastatin and cholestyramine alone and combined in patients with hypercholesterolemia. Pravastatin Multicenter Study Group IIQ70749778
Regulation of bile acid synthesis in humans: studies on cholesterol 7 alpha-hydroxylation in vivoQ71450213
Effect of the interruption of enterohepatic circulation of bile acids by cholestyramine on apolipoprotein gene expression in the ratQ72184187
Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AIQ73229704
Effect of cholesterol, cholic acid and cholestyramine administration on the intestinal mRNA expressions related to cholesterol and bile acid metabolism in the ratQ80323234
P921main subjectbiomarkerQ864574
hepatotoxicityQ1349821
P304page(s)42
P577publication date2014-08-03
P1433published inBMC pharmacology & toxicologyQ27724429
P1476titleBenign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine
P478volume15