Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV

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Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1086/653497
P8608Fatcat IDrelease_fmea5ieqcjeqrjnwmm2mly63sq
P932PMC publication ID2913975
P698PubMed publication ID20533872
P5875ResearchGate publication ID44659507

P50authorJames M OleskeQ39273703
Susan BroglyQ45413807
Jack MoyeQ56856588
P2093author name stringMiriam C Chernoff
Kathleen M Malee
Russell B Van Dyke
William A Meyer
Wendy G Mitchell
Marilyn J Crain
Peggy R Borum
George R Seage Iii
Heather M Ford-Chatterton
P2860cites workAssessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitorsQ24536268
Maternal and infant factors associated with failure to thrive in children with vertically transmitted human immunodeficiency virus-1 infection: the prospective, P2C2 human immunodeficiency virus multicenter studyQ28365722
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analoguesQ28373514
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Epidemiology and treatment of mitochondrial disordersQ34386766
Prevalence of mitochondrial DNA disease in adultsQ34691723
Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspectiveQ35550221
Genetic features of mitochondrial respiratory chain disordersQ35593189
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.Q35606742
Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymeraseQ35607523
Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease.Q35909841
Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence?Q36239813
Mitochondrial dysfunction in AIDS and its treatmentQ81110778
Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individualsQ81191235
Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapyQ36313228
Current concepts in the diagnosis and management of metabolic complications of HIV infection and its therapy.Q36555731
Molecular genetic and clinical aspects of mitochondrial disorders in childhoodQ36766110
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected childrenQ36800856
Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cellsQ36803931
Mechanisms of antiretroviral therapy-induced mitochondrial dysfunctionQ37447274
Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapyQ37492507
Incidence of opportunistic and other infections in HIV-infected children in the HAART era.Q38467275
Highly active antiretroviral therapy (HAART)-associated lactic acidosis: in vitro effects of combination of nucleoside analogues and protease inhibitors on mitochondrial function and lactic acid production.Q39299561
Greater and more rapid depletion of mitochondrial DNA in blood of patients treated with dual (zidovudine+didanosine or zidovudine+zalcitabine) vs. single (zidovudine) nucleoside reverse transcriptase inhibitorsQ39391662
Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group studyQ40396667
Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitorsQ40693184
Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitineQ42596690
Mitochondrial disorders: a proposal for consensus diagnostic criteria in infants and childrenQ44213543
Factors Associated With Mitochondrial Dysfunction in Circulating Peripheral Blood Lymphocytes From HIV-Infected PeopleQ44591425
The clinical spectrum of mitochondrial disease in 75 pediatric patientsQ44644971
Mitochondrial effects of antiretroviral therapies in asymptomatic patients.Q44811840
Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudineQ44954259
Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretroviralsQ45051217
Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapiesQ46667574
Minimum birth prevalence of mitochondrial respiratory chain disorders in childrenQ47835071
Changes in body composition and mitochondrial nucleic acid content in patients switched from failed nucleoside analogue therapy to ritonavir-boosted indinavir and efavirenz.Q50725587
Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy.Q51650745
In utero nucleoside reverse transcriptase inhibitor exposure and cancer in HIV-uninfected children: an update from the pediatric AIDS clinical trials group 219 and 219C cohorts.Q51942604
A model of the nuclear control of mitochondrial DNA replication.Q52017733
Antiretroviral Treatment in Pediatric HIV Infection in the United States From Clinical Trials to Clinical PracticeQ58285674
Antiretroviral nucleoside and nucleotide analogues and mitochondriaQ61928346
Mitochondrial disease criteria: Diagnostic applications in childrenQ62671343
Effects of coding dictionary on signal generation: a consideration of use of MedDRA compared with WHO-ARTQ74318099
Toward a pharmacogenetic understanding of nucleotide and nucleoside analogue toxicityQ79327315
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophyQ79690105
Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-infected individualsQ79817086
Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patientsQ80239731
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectanti-retroviral agentQ50430310
P304page(s)291-301
P577publication date2010-07-01
P1433published inJournal of Infectious DiseasesQ4051141
P1476titlePossible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV
P478volume202

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cites work (P2860)
Q36941650Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: a view from the United States of America
Q34881120Cardiac effects of in-utero exposure to antiretroviral therapy in HIV-uninfected children born to HIV-infected mothers
Q89615834Cellular stress responses and dysfunctional Mitochondrial-cellular senescence, and therapeutics in chronic respiratory diseases
Q30402510Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts
Q34150710HIV Infection, Inflammation, Immunosenescence, and Aging
Q30416349Hearing loss among HIV-seropositive and HIV-seronegative men and women
Q30523969Hearing loss in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents
Q35848277Language impairment in children perinatally infected with HIV compared to children who were HIV-exposed and uninfected
Q47201399Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART.
Q35073479Neurocognitive functioning in a Romanian cohort of young adults with parenterally-acquired HIV-infection during childhood
Q39244930Performance of clinical criteria for screening of possible antiretroviral related mitochondrial toxicity in HIV-infected children in Accra
Q36509694Physical fitness in children infected with the human immunodeficiency virus: associations with highly active antiretroviral therapy
Q37111533Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy.
Q36929688The Use of the Medical Dictionary for Regulatory Activities in the Identification of Mitochondrial Dysfunction in HIV-Infected Children
Q38366365Tolerance of the newborn to antiretroviral drug exposure in utero

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