BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model

scientific article

BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.03368-14
P932PMC publication ID4249364
P698PubMed publication ID25155605

P50authorDena GraysonQ20758232
Donald F SmeeQ66732853
John D MorreyQ66760143
P2093author name stringJustin G Julander
William P Sheridan
Shanta Bantia
Yarlagadda S Babu
Pravin Kotian
Brian R Taubenheim
P2860cites workComparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster modelQ27478175
Activity of T-1106 in a Hamster Model of Yellow Fever Virus InfectionQ27480272
In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus InfectionsQ27481401
Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106Q27487527
Experimental yellow fever virus infection in the golden hamster (Mesocricetus auratus) III. Clinical laboratory values.Q33371482
Efficacy of 2'-C-methylcytidine against yellow fever virus in cell culture and in a hamster modelQ33856419
Treatment of yellow feverQ34008580
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.Q34040052
Efficacy of post-exposure treatment of yellow fever with ribavirin in a hamster model of the diseaseQ34350325
Yellow fever: a disease that has yet to be conqueredQ34557933
Treatment of yellow fever virus with an adenovirus-vectored interferon, DEF201, in a hamster modelQ34933362
Immune correlates of protection against yellow fever determined by passive immunization and challenge in the hamster modelQ35141448
Experimental therapies for yellow feverQ36586306
The dengue vector Aedes aegypti: what comes nextQ37680253
Review of the risks and benefits of yellow fever vaccination including some new analysesQ38006992
Experimental yellow fever virus infection in the Golden Hamster (Mesocricetus auratus). I. Virologic, biochemical, and immunologic studiesQ39518371
Experimental yellow fever virus infection in the Golden hamster (Mesocricetus auratus). II. PathologyQ39607499
Inactivated yellow fever 17D vaccine: development and nonclinical safety, immunogenicity and protective activityQ40362914
Pathophysiologic correlations in a rhesus monkey model of yellow fever with special observations on the acute necrosis of B cell areas of lymphoid tissuesQ40854564
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectyellow feverQ154874
yellow fever virusQ836749
P304page(s)6607-6614
P577publication date2014-08-25
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleBCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model
P478volume58

Reverse relations

cites work (P2860)
Q37415438A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein.
Q64359221An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice
Q37077376BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease
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Q38546746Development of Small-Molecule Antivirals for Ebola
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Q114704017Flavivirus enzymes and their inhibitors
Q59359898Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters
Q33439713Hemorrhagic fever of bunyavirus etiology: disease models and progress towards new therapies
Q56395905Immunogenicity and Protection After Vaccination With a Modified Vaccinia Virus Ankara-Vectored Yellow Fever Vaccine in the Hamster Model
Q92471636New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections
Q47558305Nonhuman Primate Models of Zika Virus Infection, Immunity, and Therapeutic Development
Q54256710Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses.
Q29994672Offering patients more: how the West Africa Ebola outbreak can shape innovation in therapeutic research for emerging and epidemic infections
Q37203877Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection
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