Radicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry

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Radicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry is …
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scholarly articleQ13442814

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P356DOI10.1016/J.FREERADBIOMED.2010.04.010
P8608Fatcat IDrelease_cldg7lde5vdl7o7sxbfft6uz4a
P932PMC publication ID2916040
P698PubMed publication ID20406679
P5875ResearchGate publication ID43226617

P2093author name stringRichard J Johnson
George N Henderson
Alexander Angerhofer
Kyung Mee Kim
Christine Gersch
Witcha Imaram
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Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?Q35111714
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formationQ36341086
Reactions of peroxynitrite with uric acid: formation of reactive intermediates, alkylated products and triuret, and in vivo production of triuret under conditions of oxidative stressQ37342840
Chemical biology of peroxynitrite: kinetics, diffusion, and radicals.Q37408232
Spin trapping: ESR parameters of spin adductsQ39163653
Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicalsQ42116085
Direct oxidation of boronates by peroxynitrite: mechanism and implications in fluorescence imaging of peroxynitrite.Q42202476
Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometryQ43124698
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanismQ43801315
Triuret: a novel product of peroxynitrite-mediated oxidation of urateQ44761622
Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase.Q46553765
Radical acetylation of 2'-deoxyguanosine and L-histidine coupled to the reaction of diacetyl with peroxynitrite in aerated mediumQ46686567
Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxideQ67509483
On-line electrochemistry/thermospray/tandem mass spectrometry as a new approach to the study of redox reactions: the oxidation of uric acidQ69715100
Free radical metabolite of uric acidQ69816664
Synthesis of Peroxynitrite in a Two-Phase System Using Isoamyl Nitrite and Hydrogen PeroxideQ71138583
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidantsQ71721996
Oxidation of acetaldehyde by peroxynitrite and hydrogen Peroxide/Iron(II). Production Of acetate, formate, and methyl radicalsQ73091988
Peroxynitrite-mediated decarboxylation of pyruvate to both carbon dioxide and carbon dioxide radical anionQ73571198
Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acidQ73699279
P433issue2
P304page(s)275-281
P577publication date2010-04-18
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleRadicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry
P478volume49

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cites work (P2860)
Q92638386A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster
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