A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells

scientific article

A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM.4103
P932PMC publication ID5549556
P698PubMed publication ID27213817

P50authorDita GratzingerQ40447127
Michael CorcesQ43092568
Dirk StrunkQ45503167
Katharina SchallmoserQ50648053
Andreas ReinischQ56930266
P2093author name stringRavindra Majeti
Daniel Thomas
Xiaohua Zhang
Wan-Jen Hong
M Ryan Corces
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PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype.Q51076563
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Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.Q52877857
CD19-CD45 low/- CD38 high/CD138+ plasma cells enrich for human tumorigenic myeloma cells.Q53370464
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.Q53520724
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Highly purified primitive hematopoietic stem cells are PML-RARA negative and generate nonclonal progenitors in acute promyelocytic leukemia.Q54175138
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The total marrow mass of the mouse: a simplified method of measurementQ71316089
PML/RAR alpha fusion gene is expressed in both granuloid/macrophage and erythroid colonies in acute promyelocytic leukaemiaQ72311480
Cell lineage specific involvement in acute promyelocytic leukaemia (APL) using a combination of May-Grünwald-Giemsa staining and fluorescence in situ hybridization techniques for the detection of the translocation t(15;17)(q22;q12)Q77476747
NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regenerationQ79309659
The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneityQ81606570
Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cellsQ84251637
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectbone marrowQ546523
leukemiaQ29496
P304page(s)812-821
P577publication date2016-05-23
P1433published inNature MedicineQ1633234
P1476titleA humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells
P478volume22