Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats

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Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BRAINRES.2010.05.095
P932PMC publication ID2916930
P698PubMed publication ID20553876
P5875ResearchGate publication ID44678770

P2093author name stringEmilio R Garrido-Sanabria
Luis F Pacheco Otalora
Massoud F Arshadmansab
Frank Skinner
Hans-Günther Knaus
Boris S Ermolinsky
Carlos F Mello
Ileana Garcia
Mauro S Oliveira
P2860cites workModulators of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels and their Therapeutic IndicationsQ22305804
Small-conductance, calcium-activated potassium channels from mammalian brainQ24318679
Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channelsQ24564966
A human intermediate conductance calcium-activated potassium channelQ24654684
Small conductance Ca2+-activated K+ channels and calmodulinQ24678202
Small conductance Ca2+-activated K+ channels modulate synaptic plasticity and memory encodingQ28216064
Modification of seizure activity by electrical stimulation. II. Motor seizureQ28236678
Functions of SK channels in central neuronsQ28241766
Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime)Q28286744
Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cellsQ28343978
Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channelsQ28344086
Initiation of network bursts by Ca2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsyQ28361757
Temporal lobe epilepsy: where do the seizures really begin?Q30435240
K(+)-channel openers suppress epileptiform activities induced by 4-aminopyridine in cultured rat hippocampal neuronsQ46201828
Anticonvulsant effects of the BK-channel antagonist paxillineQ46215516
1-Ethyl-2-benzimidazolinone (EBIO) suppresses epileptiform activity in in vitro hippocampus.Q46579717
Hyperpolarizing potentials in guinea pig hippocampal CA3 neurons.Q46863145
Memory processing and apamin induce immediate early gene expression in mouse brainQ48309378
Inhibition of apamin-sensitive calcium dependent potassium channels facilitate the induction of long-term potentiation in the CA1 region of rat hippocampus in vitro.Q48375923
Calcium-activated afterhyperpolarizations regulate synchronization and timing of epileptiform bursts in hippocampal CA3 pyramidal neuronsQ48421576
Abnormal mGluR2/3 expression in the perforant path termination zones and mossy fibers of chronically epileptic rats.Q48490338
Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitroQ48628862
Effect of apamin, a toxin that inhibits Ca(2+)-dependent K+ channels, on learning and memory processesQ48707301
Voltage-clamp analysis of the potentiation of the slow Ca2+-activated K+ current in hippocampal pyramidal neurons.Q51404156
Differential distribution of three Ca(2+)-activated K(+) channel subunits, SK1, SK2, and SK3, in the adult rat central nervous system.Q53911073
Control of epileptiform burst rate by CA3 hippocampal cell afterhyperpolarizations in vitroQ69663857
Epileptiform burst afterhyperolarization: calcium-dependent potassium potential in hippocampal CA1 pyramidal cellsQ71416535
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca(2+)-activated K(+) channelQ73435021
Relationship between large conductance calcium-activated potassium channel and bursting activityQ73571701
In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsantQ80152918
Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in ratQ80176957
Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels.Q30471958
Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsyQ30485454
Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsyQ33320921
Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brainQ33560844
GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanismQ33606875
Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currentsQ33701513
Excitation and inhibition in temporal lobe epilepsy: a close encounter.Q33748554
Temporal lobe epilepsy surgery: definition of candidacyQ33929608
What is GABAergic inhibition? How is it modified in epilepsy?Q34041405
Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cellsQ34314205
"Epileptic neurons" in temporal lobe epilepsyQ34604299
Temporal lobe epilepsy -current wisdomQ34961163
Small conductance Ca2+-activated K+ channels as targets of CNS drug developmentQ35793863
Impaired and repaired inhibitory circuits in the epileptic human hippocampusQ36146236
Clinical aspects of temporal/limbic epilepsy and their relationships to intractability.Q36355818
Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats.Q37000100
Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: a comparative real-time PCR analysisQ37102095
Mechanism of increased BK channel activation from a channel mutation that causes epilepsy.Q37124257
Synergistic roles of GABAA receptors and SK channels in regulating thalamocortical oscillationsQ37265945
Molecular and cellular basis of epileptogenesis in symptomatic epilepsyQ37286638
Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other conceptsQ37352151
Functions and modulation of neuronal SK channelsQ37572459
Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons.Q40342294
Specific enhancement of SK channel activity selectively potentiates the afterhyperpolarizing current I(AHP) and modulates the firing properties of hippocampal pyramidal neurons.Q40359725
The pilocarpine model of epilepsyQ40463975
How long does it take for partial epilepsy to become intractable?Q40608293
The pathophysiology of human mesial temporal lobe epilepsyQ40615836
Small conductance Ca2+-activated K+ channels and calmodulin: cell surface expression and gating.Q40649619
Pathogenesis of mesial temporal sclerosis.Q40772151
Pharmacological characterisation of the human small conductance calcium-activated potassium channel hSK3 reveals sensitivity to tricyclic antidepressants and antipsychotic phenothiazinesQ40804141
Excitation and inhibition in epilepsyQ41156248
Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channelsQ42148855
Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysisQ42250713
Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brainQ42464133
Upregulation of a T-type Ca2+ channel causes a long-lasting modification of neuronal firing mode after status epilepticus.Q43972759
Regional differences in distribution and functional expression of small-conductance Ca2+-activated K+ channels in rat brain.Q44213481
The small conductance Ca2+-activated K+ channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neuronsQ44326165
SKCa channels mediate the medium but not the slow calcium-activated afterhyperpolarization in cortical neurons.Q44835120
A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor.Q44919593
Acquired dendritic channelopathy in temporal lobe epilepsyQ44992557
Protein kinase CK2 is coassembled with small conductance Ca(2+)-activated K+ channels and regulates channel gatingQ45055667
Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting.Q45999480
Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy.Q46082573
P407language of work or nameEnglishQ1860
P1104number of pages13
P304page(s)187-199
P577publication date2010-06-08
P1433published inBrain ResearchQ4955782
P1476titleAltered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats
P478volume1348

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