scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | J F Westphal | |
P2860 | cites work | Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues | Q24633406 |
The fate of naringin in humans: A key to grapefruit juice-drug interactions? | Q28291236 | ||
Potentially fatal interaction between erythromycin and disopyramide | Q28339582 | ||
A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. | Q52306429 | ||
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. | Q52534774 | ||
Concomitant digoxin toxicity and warfarin interaction in a patient receiving clarithromycin. | Q53343412 | ||
Potential interaction between clarithromycin and warfarin. | Q53357847 | ||
Clinical ergotism with lingual ischemia induced by clarithromycin-ergotamine interaction. | Q53726625 | ||
Reversal of drug resistance by erythromycin: erythromycin increases the accumulation of actinomycin D and doxorubicin in multidrug-resistant cells. | Q53827442 | ||
Drug interactions and hepatitis produced by some macrolide antibiotics | Q57314144 | ||
Decreased intestinal CYP3A in celiac disease: Reversal after successful gluten-free diet: A potential source of interindividual variability in first-pass drug metabolism* | Q58812433 | ||
Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation* | Q60787070 | ||
From the Food and Drug Administration | Q67493197 | ||
Oxidation of quinidine by human liver cytochrome P-450 | Q69598283 | ||
Effect of erythromycin on theophylline kinetics | Q70197412 | ||
QT interval prolongation and torsades de pointes due to erythromycin lactobionate | Q71003393 | ||
Cisapride and fatal arrhythmia | Q71133416 | ||
Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin | Q71579159 | ||
Identification of human liver cytochrome P450s involved in the microsomal metabolism of the antihistaminic drug loratadine | Q71883165 | ||
Possible interaction between azithromycin and cyclosporin: a case report | Q71898765 | ||
Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats | Q72217214 | ||
Steady-state pharmacokinetics of theophylline in COPD patients treated with dirithromycin | Q72572985 | ||
Inhibition of terfenadine metabolism. Pharmacokinetic and pharmacodynamic consequences | Q72793332 | ||
Life-threatening interaction between clarithromycin and disopyramide | Q73048067 | ||
Interaction between tacrolimus and erythromycin | Q73065823 | ||
Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin | Q73503614 | ||
Reduced serum theophylline concentrations after discontinuation of azithromycin: evidence for an unusual interaction | Q73571447 | ||
Possible increased anticoagulation effect of warfarin induced by azithromycin | Q74296411 | ||
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations | Q77206225 | ||
Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences | Q77360269 | ||
The Influence of Dirithromycin on the Pharmacokinetics of Cyclosporine in Healthy Subjects and in Renal Transplant Patients | Q77649359 | ||
P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies | Q78175427 | ||
Loratadine administered concomitantly with erythromycin: pharmacokinetic and electrocardiographic evaluations | Q33173569 | ||
Long QT Syndrome During High-Dose Cisapride | Q33173733 | ||
Intravenous azithromycin. | Q33543121 | ||
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein | Q34040187 | ||
Characterization of human liver cytochromes P-450 involved in theophylline metabolism | Q34538533 | ||
The effect of erythromycin on the disposition kinetics of warfarin | Q34712426 | ||
Theophylline N-demethylations as probes for P4501A1 and P4501A2. | Q34724083 | ||
Erythromycin-associated ergotamine intoxication: arteriographic and electrophysiologic analysis of a rare cause of severe ischemia of the lower extremities and associated ischemic neuropathy | Q34729824 | ||
Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6). | Q34756683 | ||
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes | Q35608569 | ||
Pharmacokinetic drug interactions of macrolides | Q35759081 | ||
Drug metabolism by cytochromes P450 in the liver and small bowel. | Q35787791 | ||
Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine | Q36053651 | ||
The mechanism of cyclosporine toxicity induced by clarithromycin | Q36093902 | ||
Pharmacokinetic drug interactions with cyclosporin (Part I). | Q37956836 | ||
Cisapride: a gastrointestinal prokinetic drug | Q38570021 | ||
Decreased antipyrine clearance following endotoxin administration: in vivo evidence of the role of nitric oxide. | Q39472190 | ||
Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration | Q39558497 | ||
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers | Q39864969 | ||
Macrolide antibacterials. Drug interactions of clinical significance | Q40423079 | ||
Recent Advances: the Cytochrome P450 Enzymes | Q40475823 | ||
Possible inhibition of hepatic metabolism of quinidine by erythromycin | Q40575062 | ||
A review of clinical trials comparing HMG-CoA reductase inhibitors | Q40630809 | ||
Hepatic side-effects of antibiotics | Q40677434 | ||
Antipyrine clearance in pneumonia | Q40817512 | ||
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin | Q40851439 | ||
Clinical pharmacokinetics of newer antibacterial agents in liver disease | Q40884111 | ||
Macrolides versus azalides: a drug interaction update | Q40938716 | ||
Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein | Q41018603 | ||
Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. | Q41142887 | ||
Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology. | Q41143946 | ||
Theophylline metabolism in human liver microsomes: inhibition studies. | Q41220959 | ||
Human P450 metabolism of warfarin | Q41334623 | ||
Drug interactions of macrolides: emphasis on dirithromycin | Q41380268 | ||
Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450. | Q41462331 | ||
Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney | Q41531879 | ||
Human P-glycoprotein transports cyclosporin A and FK506. | Q41565344 | ||
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). | Q41596609 | ||
Inhibition by erythromycin of the conversion of carbamazepine to its active 10,11-epoxide metabolite | Q41772429 | ||
Age as a determinant of sensitivity to warfarin | Q41946702 | ||
Polymorphisms in oxidative drug metabolism: relationship to food preference | Q42284944 | ||
Torsade de pointes induced by cisapride/clarithromycin interaction | Q42536187 | ||
Erythromycin-induced clozapine toxic reaction | Q42556498 | ||
Seizure following addition of erythromycin to clozapine treatment | Q42563091 | ||
The influence of cisapride and clarithromycin on QT intervals in healthy volunteers. | Q42687064 | ||
Cyclosporin metabolism by human gastrointestinal mucosal microsomes | Q43224335 | ||
Erythromycin enhances the absorption of cyclosporin | Q43229096 | ||
Inhibition of theophylline metabolism by interferon | Q43898227 | ||
Effect of erythromycin in patients receiving long-term warfarin therapy. | Q46148539 | ||
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction | Q46791680 | ||
The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. | Q50867766 | ||
Interaction between midazolam and clarithromycin: comparison with azithromycin. | Q51563397 | ||
A potentially hazardous interaction between erythromycin and midazolam. | Q51670697 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | clarithromycin | Q118551 |
azithromycin | Q165399 | ||
P304 | page(s) | 285-295 | |
P577 | publication date | 2000-10-01 | |
P1433 | published in | British Journal of Clinical Pharmacology | Q176044 |
P1476 | title | Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin | |
P478 | volume | 50 |
Q40418279 | A pulmonary mass caused by Rhodococcus equi infection in a renal transplant recipient |
Q52776107 | A review of the infection pathogenesis and prophylaxis recommendations in patients with chronic lymphocytic leukemia. |
Q35859961 | Azithromycin and warfarin interaction |
Q34466778 | Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system |
Q94563599 | Calculated initial parenteral treatment of bacterial infections: Pharmacokinetics and pharmacodynamics |
Q47985538 | Clarithromycin, a cytochrome P450 inhibitor, can reverse mefloquine resistance in Plasmodium yoelii nigeriensis- infected Swiss mice |
Q43246296 | Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine |
Q38123117 | Clinical hypotension with co-prescription of macrolide antibiotics and calcium-channel blockers in haemodialysis patients: a retrospective chart review. |
Q33163019 | Comparing two types of macrolide antibiotics for the purpose of assessing population-based drug interactions |
Q52318495 | Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives. |
Q26748532 | Corticosteroids in the adjunctive therapy of community-acquired pneumonia: an appraisal of recent meta-analyses of clinical trials |
Q26749480 | Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians' Perspectives |
Q36429699 | Drug interactions during therapy with three major groups of antimicrobial agents |
Q64331279 | Drug interactions of meglitinide antidiabetics involving CYP enzymes and OATP1B1 transporter |
Q37770556 | Drug-drug interaction profiles of proton pump inhibitors |
Q46459661 | Effect of clarithromycin on the enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes |
Q41878009 | Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function |
Q45004280 | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism |
Q38178836 | Efficacy and safety of long-term antibiotics (macrolides) for the treatment of chronic rhinosinusitis |
Q39997520 | Evaluation of potential interaction between vinorelbine and clarithromycin |
Q35196196 | Factors affecting the clinical development of cytochrome p450 3A substrates |
Q46907846 | Identification of severe potential drug-drug interactions using an Italian general-practitioner database. |
Q36779660 | Immunomodulatory effects of macrolide antibiotics in respiratory disease: therapeutic implications for asthma and cystic fibrosis |
Q37591508 | Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions |
Q92283346 | Improving antibacterial prescribing safety in the management of COPD exacerbations: systematic review of observational and clinical studies on potential drug interactions associated with frequently prescribed antibacterials among COPD patients |
Q39115811 | In vitro studies on flubromazolam metabolism and detection of its metabolites in authentic forensic samples |
Q80363823 | Lack of Interaction between Modified-Release Fluvastatin and Amlodipine in Healthy Subjects |
Q38248677 | Liver injury associated with ketoconazole: review of the published evidence |
Q42016590 | Macrolide therapy in chronic inflammatory diseases |
Q43137163 | Macrolide-theophylline interactions: no role for the inhibition of cytochrome P4501A2. |
Q30406048 | Management of nontuberculous mycobacterial infection in the elderly |
Q37638755 | Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective |
Q43058205 | Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case report |
Q44401287 | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics |
Q34458355 | Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions |
Q90003782 | Pharmacotherapy Pearls in Rheumatology for the Care of Older Adult Patients: Focus on Oral Disease-Modifying Antirheumatic Drugs and the Newest Small Molecule Inhibitors |
Q38731918 | Pharmacotherapy for community-acquired pneumonia in the elderly. |
Q62490640 | Preparing next-generation scientists for biomedical big data: artificial intelligence approaches |
Q36199356 | Reductions in Use of Colchicine after FDA Enforcement of Market Exclusivity in a Commercially Insured Population. |
Q97569685 | Reply to Gautret et al: hydroxychloroquine sulfate and azithromycin for COVID-19: what is the evidence and what are the risks? |
Q37397811 | Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction |
Q41952910 | Rhabdomyolysis following a short course of clarythromycin |
Q35088420 | Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4. |
Q26770501 | Roflumilast: a review of its use in the treatment of COPD |
Q28243911 | Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes |
Q46109640 | Short-term clarithromycin administration impairs clearance and enhances pharmacodynamic effects of trazodone but not of zolpidem |
Q46619247 | Statin-macrolide interaction risk: a population-based study throughout a general practice database. |
Q93054280 | The gut microbiome: an orchestrator of xenobiotic metabolism |
Q43227521 | The macrolide clarithromycin inhibits experimental post-transplant bronchiolitis obliterans |
Q34586375 | The pharmacological importance of cytochrome CYP3A4 in the palliation of symptoms: review and recommendations for avoiding adverse drug interactions |
Q34589838 | The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers |
Q36871056 | Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs |
Q38458352 | Translating the genetics of cystic fibrosis to personalized medicine |
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Q79242592 | [Cytochrom-P450 mediated drug interactions caused by antibiotics] |