Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation

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Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...625888P
P356DOI10.1371/JOURNAL.PONE.0025888
P932PMC publication ID3189933
P698PubMed publication ID22016782
P5875ResearchGate publication ID51733481

P50authorMichele SavianoQ42602207
Gianna PalmieriQ55756045
Ramanath N HegdeQ56988501
Emma LangellaQ56988514
Paolo BergamoQ56988528
Alberto LuiniQ56988538
Mosè RossiQ69556253
Menotti RuvoQ88043792
Marta GogliettinoQ114375367
P2093author name stringAnnamaria Sandomenico
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Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell linesQ41602118
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Multiple proteolytic systems, including the proteasome, contribute to CFTR processingQ50337154
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Acetylation: a regulatory modification to rival phosphorylation?Q29614886
Degradation of CFTR by the ubiquitin-proteasome pathwayQ29616142
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Cotranslational amino-terminal processing of cytosolic proteins. Cell-free expression of site-directed mutants of human hemoglobinQ30404689
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N-terminal acetylation of cellular proteins creates specific degradation signalsQ34095411
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Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation.Q34268195
The tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residueQ34333425
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Activation of the cell death program by inhibition of proteasome functionQ35964722
Proteasome inhibition as a novel therapeutic target in human cancer.Q36014046
Catabolism of intracellular N-terminal acetylated proteins: involvement of acylpeptide hydrolase and acylaseQ36145998
Influence of proteasome inhibitors on apoptosisQ36380960
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The proteasome as a potential target for novel anticancer drugs and chemosensitizersQ36695969
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Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.Q52968368
Refinement of the structure of Escherichia coli-derived rat intestinal fatty acid binding protein with bound oleate to 1.75-A resolution. Correlation with the structures of the apoprotein and the protein with bound palmitateQ54668658
A novel class of protease targets of phosphatidylethanolamine-binding proteins (PEBP): a study of the acylpeptide hydrolase and the PEBP inhibitor from the archaeon Sulfolobus solfataricusQ57599845
Proteolysis: from the lysosome to ubiquitin and the proteasomeQ81354981
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)e25888
P577publication date2011-10-10
P1433published inPLOS OneQ564954
P1476titleAcylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation
P478volume6

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