| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1014172811 |
| P356 | DOI | 10.1038/ONC.2014.3 |
| P932 | PMC publication ID | 4135037 |
| P698 | PubMed publication ID | 24531709 |
| P5875 | ResearchGate publication ID | 260211173 |
| P50 | author | Philipp Kaldis | Q56798414 |
| P2093 | author name string | X Liu | |
| L Sun | |||
| D Ray | |||
| H Kiyokawa | |||
| K Christov | |||
| D Nimbalkar | |||
| M P Gillam | |||
| P2860 | cites work | Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors | Q24337658 |
| Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia | Q28143642 | ||
| Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1 | Q28145116 | ||
| Cdk2 knockout mice are viable | Q28210245 | ||
| Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma | Q28270834 | ||
| Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6 | Q28277471 | ||
| Cell cycle kinases in cancer | Q28282263 | ||
| Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c | Q28506197 | ||
| Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number | Q28584893 | ||
| Requirement for CDK4 kinase function in breast cancer | Q28585905 | ||
| A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors | Q28592210 | ||
| Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus | Q28592973 | ||
| Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation | Q29614736 | ||
| Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors | Q29616203 | ||
| Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity | Q33959792 | ||
| Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity | Q33965112 | ||
| The Pezcoller lecture: cancer cell cycles revisited | Q33987290 | ||
| Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). | Q34381917 | ||
| A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice | Q34381923 | ||
| Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis. | Q34887604 | ||
| CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis | Q35209756 | ||
| Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia | Q35631212 | ||
| Genetic evidence for functional dependency of p18Ink4c on Cdk4. | Q35663680 | ||
| Living with or without cyclins and cyclin-dependent kinases | Q35951291 | ||
| Molecular genetics of multiple endocrine neoplasia types 1 and 2. | Q36111935 | ||
| Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo | Q37141780 | ||
| Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective | Q37347306 | ||
| Global expression profiling of murine MEN1-associated tumors reveals a regulatory role for menin in transcription, cell cycle and chromatin remodelling. | Q38302417 | ||
| A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation | Q38442858 | ||
| Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6. | Q39320072 | ||
| MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells | Q39942574 | ||
| Cdk4 is indispensable for postnatal proliferation of the anterior pituitary. | Q40509439 | ||
| Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity | Q42490110 | ||
| The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells | Q44000669 | ||
| The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells | Q44333291 | ||
| Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice | Q44662277 | ||
| IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice. | Q45879291 | ||
| Cdc2-cyclin E complexes regulate the G1/S phase transition | Q46592665 | ||
| Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice | Q48823384 | ||
| Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. | Q53572786 | ||
| Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941] | Q56893811 | ||
| Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1 | Q73557853 | ||
| Somatic mutations in MEN type 1 tumors, consistent with the Knudson "two-hit" hypothesis | Q74494218 | ||
| A role of FRK in regulation of embryonal pancreatic beta cell formation | Q80116585 | ||
| Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation | Q83296429 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 932-938 | |
| P577 | publication date | 2014-02-17 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2. | |
| P478 | volume | 34 |
| Q36486988 | Animal models of pituitary neoplasia |
| Q35963331 | CDK4 and miR-15a comprise an abnormal automodulatory feedback loop stimulating the pathogenesis and inducing chemotherapy resistance in nasopharyngeal carcinoma |
| Q37693690 | Cell cycle proteins as promising targets in cancer therapy |
| Q35082433 | Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studies |
| Q91789132 | Is there a CDKN2A-centric network in pancreatic ductal adenocarcinoma? |
| Q48536956 | Non-canonical roles of PFKFB3 in regulation of cell cycle through binding to CDK4. |
| Q58616038 | Pituitary Gene Signalling Pathway |
| Q52738997 | Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling. |
| Q47393972 | Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets |
| Q34405462 | Telomere dysfunction suppresses multiple endocrine neoplasia in mice |
| Q47814736 | The future: genetics advances in MEN1 therapeutic approaches and management strategies. |
| Q38274982 | The role of genetic and epigenetic changes in pituitary tumorigenesis |
| Q90542917 | siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn's Disease |
| Q94076162 | siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn's Disease |
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