A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice

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A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1004420798
P356DOI10.1007/S00380-011-0183-8
P698PubMed publication ID22038107

P2093author name stringYu Zhang
Jingjing Liu
Huiyong Zhang
Yong Lu
Qiyan Xiong
Yunxiao Sun
Xiangbing Hu
Xiying Tan
P2860cites work8 Use of glutaraldehyde as a coupling agent for proteins and peptidesQ54665437
Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65-kDa heat shock protein, to its 180-188 peptide, and to a partially homologous peptide of the proteoglycan link proteinQ68234416
Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosisQ72209255
Epitope specificity of anti-heat shock protein 65/60 serum antibodies in atherosclerosisQ73221024
Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65Q74598447
Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient miceQ77350543
Defining a T-cell epitope within HSP 65 in recurrent aphthous stomatitisQ78031832
HSP-derived peptides inducing uveitis and IgG and IgA antibodiesQ78173323
Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesisQ79326709
Association of serum antibodies to heat-shock protein 65 with coronary calcification levels: suggestion of pathogen-triggered autoimmunity in early atherosclerosisQ79353804
Atherosclerosis in Behçet's SyndromeQ80553194
Anti-heat shock protein 60 autoantibodies induce atherosclerosis in apolipoprotein E-deficient mice via endothelial damageQ81098943
T cells against the pathogenic and protective epitopes of heat-shock protein 65 are crossreactive and display functional similarity: novel aspect of regulation of autoimmune arthritisQ81442959
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
Immune mechanisms in atherosclerosisQ34462668
Role of heat shock proteins in atherosclerosisQ34960748
Thematic review series: The immune system and atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease?Q36049902
Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritisQ36377048
T-cell costimulation and coinhibition in atherosclerosis.Q37143018
Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosisQ37209541
The role of adaptive T cell immunity in atherosclerosisQ37339539
Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptomsQ37425852
Management of cardiovascular disease risk in chronic inflammatory disordersQ37428743
Comparison of the clinical features of recurrent aphthous stomatitis and Behçet's diseaseQ37528639
Inflammatory mechanisms in atherosclerosisQ37561655
Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosisQ37869622
Infections, immunity, and atherosclerosis: associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosisQ37875835
Macrophage migration inhibitory factor governs endothelial cell sensitivity to LPS-induced apoptosisQ39523844
Circulating levels of autoantibodies to oxidized low-density lipoprotein and C-reactive protein levels correlate with endothelial function in resistance arteries in men with coronary heart diseaseQ39990700
Macrophage-lysis mediated by autoantibodies to heat shock protein 65/60.Q41135115
Expression of heat shock proteins and nitrotyrosine in small arteries from patients with coronary heart disease.Q45922502
Anti-endothelial cell antibodies from lupus patients bind to apoptotic endothelial cells promoting macrophage phagocytosis but do not induce apoptosisQ46435109
Comparative analysis of linear antibody epitopes on human and mycobacterial 60-kDa heat shock proteins using samples of healthy blood donors.Q47620561
P433issue4
P921main subjectMycobacterium tuberculosisQ130971
atherosclerosisQ12252367
P304page(s)411-418
P577publication date2011-10-29
P1433published inHeart and VesselsQ15766690
P1476titleA novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice
P478volume27

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