Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative Escherichia coli.

scientific article published on 28 October 2011

Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative Escherichia coli. is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...627030E
P356DOI10.1371/JOURNAL.PONE.0027030
P932PMC publication ID3203933
P698PubMed publication ID22046438
P5875ResearchGate publication ID51763695

P50authorNigel KleinQ57884527
Lindsey A EdwardsQ58344241
Mona Bajaj-ElliottQ61865638
P2093author name stringAlan D Phillips
Simon H Murch
P2860cites workEnteroaggregative Escherichia coli: An Emerging Enteric Food Borne PathogenQ21328680
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Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expressionQ28211358
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.Q30305779
Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells.Q30471492
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Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in miceQ33521257
Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042Q33526331
Interleukin-8 response in an intestinal HCT-8 cell line infected with enteroaggregative and enterotoxigenic Escherichia coliQ33712186
Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptorsQ33885735
A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cellsQ33888663
A large toxin from pathogenic Escherichia coli strains that inhibits lymphocyte activationQ34003951
The immune system and the gut microbiota: friends or foes?Q34024073
Fimbriae, transmembrane signaling, and cell activationQ34136744
Intimate adherence by enteropathogenic Escherichia coli modulates TLR5 localization and proinflammatory host response in intestinal epithelial cells.Q54372966
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The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells.Q54546798
Aggregative adherence fimbriae contribute to the inflammatory response of epithelial cells infected with enteroaggregative Escherichia coli.Q54638065
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasionQ34192675
The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics.Q34415669
Bacterial outer membrane vesicles and the host-pathogen interactionQ34468123
Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cellsQ34853145
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Identification of virulence genes linked with diarrhea due to atypical enteropathogenic Escherichia coli by DNA microarray analysis and PCR.Q35073619
Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophilsQ35527637
Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli.Q35556396
Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocationQ36104202
Role of plasmid-encoded adherence factors in adhesion of enteropathogenic Escherichia coli to HEp-2 cellsQ37014804
Attaching effacing Escherichia coli and paradigms of Tir-triggered actin polymerization: getting off the pedestalQ37021415
Characterization of plasmids encoding the adherence factor of enteropathogenic Escherichia coliQ37023756
Distinctive patterns of adherence of enteropathogenic Escherichia coli to HeLa cellsQ37077312
Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines.Q37106331
Dendritic cells in intestinal immune regulation.Q37171796
Commensals, bacterial pathogens and intestinal inflammation: an intriguing ménage à troisQ37186943
Pathogenic bacteria induce colonic PepT1 expression: an implication in host defense response.Q37376348
Membrane partitioning: is location everything when it comes to endotoxin recognition?Q37769160
Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation.Q39480384
Enteroaggregative Escherichia coli Disrupts Epithelial Cell Tight JunctionsQ39658552
Identification and sequence analysis of lpfABCDE, a putative fimbrial operon of Salmonella typhimuriumQ39836359
Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand.Q39921921
EspC translocation into epithelial cells by enteropathogenic Escherichia coli requires a concerted participation of type V and III secretion systemsQ39973164
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function.Q40153854
Plasmid-encoded expression of lipopolysaccharide O-antigenic polysaccharide in enteropathogenic Escherichia coliQ40164003
Translocation of enteropathogenic Escherichia coli across an in vitro M cell model is regulated by its type III secretion system.Q40171429
Balance of bacterial pro- and anti-inflammatory mediators dictates net effect of enteropathogenic Escherichia coli on intestinal epithelial cellsQ40345219
Actin accumulation at sites of bacterial adhesion to tissue culture cells: basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coliQ40426825
In vitro and ex vivo activation of the TLR5 signaling pathway in intestinal epithelial cells by a commensal Escherichia coli strainQ40526966
Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activationQ40532416
Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis.Q40711507
EspA filament-mediated protein translocation into red blood cellsQ40813279
Modulation of host cell membrane fluidity: a novel mechanism for preventing bacterial adhesionQ40941652
Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli.Q41081300
Inhibition of localized adhesion of enteropathogenic Escherichia coli to HEp-2 cells by immunoglobulin and oligosaccharide fractions of human colostrum and breast milkQ41681597
The ex vivo response of human intestinal mucosa to enteropathogenic Escherichia coli infectionQ42287928
The Escherichia coli common pilus and the bundle-forming pilus act in concert during the formation of localized adherence by enteropathogenic E. coliQ43127737
Humoral immune response to flagellin requires T cells and activation of innate immunityQ44154163
Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: an ex vivo human organ culture study.Q44515676
Diarrhoea: why children are still dying and what can be doneQ44833665
CD14 is required for MyD88-independent LPS signaling.Q45990170
Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1.Q50096687
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
enteropathogenQ63500873
P304page(s)e27030
P577publication date2011-10-28
P1433published inPLOS OneQ564954
P1476titleBacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative Escherichia coli
P478volume6

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cites work (P2860)
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Q30410557The micronutrient zinc inhibits EAEC strain 042 adherence, biofilm formation, virulence gene expression, and epithelial cytokine responses benefiting the infected host
Q30422017The role of peroxisome proliferator-activated receptor γ in immune responses to enteroaggregative Escherichia coli infection
Q89996447Worm-Based Alternate Assessment of Probiotic Intervention against Gut Barrier Infection

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