Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha

scientific article

Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1136/ARD.59.SUPPL_1.I75
P932PMC publication ID1766633
P698PubMed publication ID11053094

P2093author name stringMaini RN
Williams RO
Feldmann M
P2860cites workTransgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritisQ24564656
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritisQ28239197
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexateQ28295474
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritisQ28306666
Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical dataQ30560117
Experimental autoimmune arthritis in mice. I. Homologous type II collagen is responsible for self-perpetuating chronic polyarthritisQ33557750
Role of TNF alpha in the induction of antigen induced arthritis in the rabbit and the anti-arthritic effect of species specific TNF alpha neutralising monoclonal antibodiesQ33567277
Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritisQ35132863
Autoimmunity to type II collagen an experimental model of arthritisQ36335891
Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4Q36350833
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblastsQ36351406
Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factorsQ36351673
Induction of arthritis in monkeys by immunization with type II collagenQ36355205
Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in miceQ37147228
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritisQ37253521
Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial jointQ37408069
Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factorQ37558444
Collagen induced arthritis as an experimental model for rheumatoid arthritis. Immunogenetics, pathogenesis and autoimmunityQ38666665
The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritisQ39475952
Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatmentQ39486764
Predominantly T-Cell Infiltrate in Rheumatoid Synovial MembranesQ39944481
Collagen arthritis as a relevant model for rheumatoid arthritisQ40338367
Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgGQ40699364
Biologic agents for treating rheumatoid arthritis. Concepts and progressQ41398093
Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritisQ44064388
Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial.Q52221782
Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.Q54729757
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.Q54784059
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor αQ56813295
Homologous type II collagen induces chronic and progressive arthritis in miceQ57352747
Immunisation against heterologous type II collagen induces arthritis in miceQ59053172
Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilageQ59063497
Therapy with monoclonal antibodies by elimination of T-cell subsets in vivoQ59082223
CD4 monoclonal antibody pairs for immunosuppression and tolerance inductionQ61651783
The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritisQ67567811
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptorQ67869949
Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alphaQ68007091
Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritisQ68028260
Stimulation of endothelial cell binding of lymphocytes by tumor necrosis factorQ68827373
Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritisQ70561942
Effect of antithymocyte serum on collagen arthritis in rats: evidence that T cells are involved in its pathogenesisQ71010017
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1RaQ71098362
Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient miceQ71555684
Major role for interleukin 1 but not for tumor necrosis factor in early cartilage damage in immune complex arthritis in miceQ71603105
The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic miceQ71889641
The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritisQ72065831
Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4Q72238634
Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritisQ72526685
Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in miceQ72620618
Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase responseQ72692349
Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA)Q73149273
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion proteinQ73502940
A comparative study into the mechanisms of action of anti-tumor necrosis factor alpha, anti-CD4, and combined anti-tumor necrosis factor alpha/anti-CD4 treatment in early collagen-induced arthritisQ73574469
DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis: characterization of the cytokine cascade and cellular compositionQ73705668
Different roles of tumour necrosis factor alpha and interleukin 1 in murine streptococcal cell wall arthritisQ77403524
Rodent models of arthritis: relevance for human diseaseQ77650347
P407language of work or nameEnglishQ1860
P921main subjectcartilageQ502730
TNFQ18032037
P304page(s)i75-80
P577publication date2000-11-01
P1433published inAnnals of the Rheumatic DiseasesQ4767876
P1476titleCartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha
P478volume59 Suppl 1

Reverse relations

cites work (P2860)
Q38274571Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis
Q47252649Effects of sesamin on primary human synovial fibroblasts and SW982 cell line induced by tumor necrosis factor-alpha as a synovitis-like model
Q35804433Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation
Q26738338Hypoxia-Inducible Factor (HIF) as a Target for Novel Therapies in Rheumatoid Arthritis
Q34786085Immunology of pregnancy-pregnancy as a remission inducing agent in rheumatoid arthritis
Q34360546Immunotherapy for rheumatoid arthritis
Q28202653Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis
Q34587358Lack of association of matrix metalloproteinase-3 gene polymorphism with susceptibility to rheumatoid arthritis: a meta-analysis
Q35083869Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis
Q51716595Low Dietary c9t11-Conjugated Linoleic Acid Intake from Dairy Fat or Supplements Reduces Inflammation in Collagen-Induced Arthritis.
Q33648802MMP-3 and MMP-8 single-nucleotide polymorphisms are related to alcohol-induced osteonecrosis of the femoral head in Chinese males
Q24536131Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice
Q47776871Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice
Q35555622Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum
Q36633235Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis
Q39389959Targeted etanercept for treatment-refractory pain due to bone metastasis: Two case reports
Q36875765The remission of rheumatoid arthritis during pregnancy
Q86340489Treatment of CIA Mice with FGF21 Down-regulates TH17-IL-17 Axis
Q53945794Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis.

Search more.