Testosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults

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Testosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults is …
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scholarly articleQ13442814

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P356DOI10.1155/2014/507395
P932PMC publication ID4140116
P698PubMed publication ID25165472
P5875ResearchGate publication ID265176423

P50authorDebra WatersQ85768654
Dennis T. VillarealQ89083473
P2093author name stringReina Armamento-Villareal
Kenneth Fowler
Lina E Aguirre
Irum Zeb Jan
P2860cites workAdiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseQ24309462
Adverse events associated with testosterone administrationQ24601802
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Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal womenQ57989064
Leptin Directly Alters Lipid Partitioning in Skeletal MuscleQ59515980
Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors studyQ59538331
Physical Fitness Is Independently Related to Blood Leptin Concentration and Insulin Sensitivity Index in Male Subjects with Central AdiposityQ61827252
Development of leptin resistance in rat soleus muscle in response to high-fat dietsQ73230187
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older womenQ73344551
Effect of testosterone treatment on body composition and muscle strength in men over 65 years of ageQ78114999
Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 StudyQ80166265
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of AgingQ31831299
Transdermal testosterone treatment in women with impaired sexual function after oophorectomyQ33916725
Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levelsQ33943952
Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging studyQ34113431
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guidelineQ34119261
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activationQ34416242
Testosterone for low libido in postmenopausal women not taking estrogenQ34873686
Weight loss, exercise, or both and physical function in obese older adultsQ35044094
Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss.Q35223390
Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitationQ35459531
Androgen treatment and muscle strength in elderly men: A meta-analysisQ35546738
Sarcopenia: effects on body composition and functionQ35590167
Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trialQ36430047
The expression of TNF alpha by human muscle. Relationship to insulin resistanceQ37352139
Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammationQ37363276
Testosterone and progesterone, but not estradiol, stimulate muscle protein synthesis in postmenopausal womenQ37428970
Adipokines as regulators of muscle metabolism and insulin sensitivityQ37486025
Obesity in older adults: relationship to functional limitationQ37617919
Menopause and sarcopenia: A potential role for sex hormonesQ37847363
Long-term effects of recombinant human GH replacement in adults with GH deficiency: a systematic reviewQ38097713
Effect of weight loss and exercise on frailty in obese older adultsQ38407531
Body fat predicts an increase and limb muscle strength predicts a decrease in leptin in older adults over 2·6 yearsQ39120514
Obesity affects nursing-care facility admission among whites but not blacksQ39612769
Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed ratsQ42170113
Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled studyQ43198484
Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men.Q43705600
Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in ratsQ43879192
Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistanceQ44030261
Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.Q45168742
Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjectsQ46318055
DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.Q47332853
Association of adiponectin with peripheral muscle status in elderly patients with heart failureQ48957110
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectobesityQ12174
testosteroneQ1318776
testosteroneQ27863114
P304page(s)507395
P577publication date2014-07-02
P1433published inInternational journal of endocrinologyQ26842119
P1476titleTestosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults
P478volume2014

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cites work (P2860)
Q33625185C-Reactive Protein and Frailty in the Elderly: A Literature Review
Q50211707Elevated serum leptin levels are associated with low vitamin D, sarcopenic obesity, poor muscle strength, and physical performance in knee osteoarthritis
Q33904206Exercise training improves free testosterone in lifelong sedentary aging men.
Q54980703Gender difference in the effects of interleukin-6 on grip strength - a systematic review and meta-analysis.
Q38640353Hand-grip strength among older adults in Singapore: a comparison with international norms and associative factors
Q38644526Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction
Q58793006Physical Fitness and Its Relationship to Plasma Leptin, Leptin Soluble Receptor, and Free Leptin Index in a Saudi Population: A Comparison Between Diabetic and Non-Diabetic Individuals

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