| P2093 | author name string | Gopinatha Suresh Kumar | |
| | Kakali Bhadra | |
| P2860 | cites work | Synthesis of linked berberine dimers and their remarkably enhanced DNA-binding affinities. | Q51485174 |
| | Sanguinarine, a phototoxic H2O2-producing alkaloid. | Q52454587 |
| | Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. | Q53421664 |
| | Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. | Q53533673 |
| | Efficient photoinduced DNA damage by coralyne. | Q53596592 |
| | In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. | Q54024638 |
| | Protonated structures of naturally occurring deoxyribonucleic acids and their interaction with berberine. | Q54484780 |
| | Variability in the yield of benzophenanthridine alkaloids in wildcrafted vs cultivated bloodroot (Sanguinaria canadensis L.) | Q57105517 |
| | Correlation of the cytotoxic activity of four different alkaloids, from Chelidonium majus (greater celandine), with their DNA intercalating properties and ability to induce breaks in the DNA of NK/Ly murine lymphoma cells | Q57245063 |
| | Inhibition of topoisomerase I function by coralyne and 5,6-dihydrocoralyne | Q30469669 |
| | Spectrometric studies of cytotoxic protoberberine alkaloids binding to double-stranded DNA. | Q33211597 |
| | The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. | Q33212646 |
| | Towards the discovery of drug-like RNA ligands? | Q33261065 |
| | Quaternary benzo[c]phenanthridine alkaloids--novel cell permeant and red fluorescing DNA probes. | Q33286733 |
| | Self-structure induction in single stranded poly(A) by small molecules: Studies on DNA intercalators, partial intercalators and groove binding molecules | Q33326916 |
| | Effect of berberine on Staphylococcus epidermidis biofilm formation | Q33401429 |
| | Solvent effects on the thermodynamics and kinetics of coralyne self-aggregation | Q33405818 |
| | Molecular aspects of small molecules-poly(A) interaction: an approach to RNA based drug design | Q33416612 |
| | Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats | Q33431509 |
| | Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids | Q34222092 |
| | The potential of alkaloids in drug discovery | Q34250093 |
| | The anti-inflammatory potential of berberine in vitro and in vivo | Q34290953 |
| | Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges | Q34401688 |
| | Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins | Q34552498 |
| | Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectives | Q34555144 |
| | Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine | Q34594086 |
| | Bax, Bcl-2, and NF-kappaB expression in sanguinarine induced bimodal cell death | Q43705076 |
| | Uncoupling of photosynthetic phosphorylation by benzophenanthridine alkaloids | Q43748528 |
| | Sequence-selective, pH-dependent binding to DNA of benzophenanthridine alkaloids | Q43906126 |
| | Small molecule-RNA interaction: spectroscopic and calorimetric studies on the binding by the cytotoxic protoberberine alkaloid coralyne to single stranded polyribonucleotides | Q43977665 |
| | The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death | Q43983993 |
| | Influence of DNA structures on the conversion of sanguinarine alkanolamine form to iminium form | Q44220158 |
| | Spectroscopic and thermodynamic studies on the binding of sanguinarine and berberine to triple and double helical DNA and RNA structures | Q44366443 |
| | Interaction of berberine with human platelet alpha 2 adrenoceptors | Q44412167 |
| | Effects of berberine on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus | Q44744808 |
| | Hepatobiliary excretion of berberine | Q44811095 |
| | Sanguinarine: an evaluation of in vivo cytogenetic activity | Q45026850 |
| | RNA targeting through binding of small molecules: Studies on t-RNA binding by the cytotoxic protoberberine alkaloid coralyne | Q45357382 |
| | Fluorescence properties of selected benzo[c]phenantridine alkaloids and studies of their interaction with CT DNA. | Q46138334 |
| | Spectroscopic and calorimetric studies on the binding of alkaloids berberine, palmatine and coralyne to double stranded RNA polynucleotides | Q46170072 |
| | Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression | Q46175838 |
| | Study on the phosphorescence characterizations of palmatine chloride on the solid substrate and its interaction with ctDNA. | Q46209713 |
| | Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells | Q46209910 |
| | Synthesis and DNA-binding affinities of monomodified berberines | Q46579923 |
| | Human topoisomerase I poisoning: docking protoberberines into a structure-based binding site model | Q46630855 |
| | Interaction of isoquinoline alkaloid palmatine with deoxyribonucleic acids: binding heterogeneity, and conformational and thermodynamic aspects | Q46637385 |
| | Molecular recognition of nucleic acids: coralyne binds strongly to poly(A). | Q46672072 |
| | Synthesis, DNA-binding affinities, and binding mode of berberine dimers | Q46709246 |
| | The binding of DNA intercalating and non-intercalating compounds to A-form and protonated form of poly(rC).poly(rG): spectroscopic and viscometric study | Q46734066 |
| | Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action | Q46745033 |
| | Hypoglycemic activity of jatrorrhizine | Q46932067 |
| | RNA specific molecules: cytotoxic plant alkaloid palmatine binds strongly to poly(A). | Q46960178 |
| | The mechanism of guanine specific photooxidation in the presence of berberine and palmatine: activation of photosensitized singlet oxygen generation through DNA-binding interaction | Q46987825 |
| | Protonated forms of poly[d(G-C)] and poly(dG).poly(dC) and Their interaction with berberine | Q47398661 |
| | L-Glutamine influx in malaria-infected erythrocytes: a target for antimalarials? | Q47995417 |
| | Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores | Q48820869 |
| | Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids | Q50211912 |
| | Mechanism of vasodilatory effect of berberine in rat mesenteric artery | Q50800161 |
| | Spacer length and attaching position-dependent binding of synthesized protoberberine dimers to double-stranded DNA. | Q51241357 |
| | Leishmania donovani: amastigote inhibition and mode of action of berberine | Q34695893 |
| | Synthesis and antimicrobial activity of 3-alkoxyjatrorrhizine derivatives | Q34755481 |
| | Synthesis and antimicrobial activity of 3-octyloxy-8-alkyljatrorrhizine derivatives | Q34980342 |
| | Rational ligand design for RNA: the role of static structure and conformational flexibility in target recognition | Q35012314 |
| | The search of DNA-intercalators as antitumoral drugs: what it worked and what did not work. | Q36002760 |
| | Effects of palmatine on potassium and calcium currents in isolated rat hepatocytes | Q36178363 |
| | The interaction of plant alkaloids with DNA. II. Berberinium chloride | Q36184304 |
| | Cross resistance pattern towards anticancer drugs of a human carcinoma multidrug-resistant cell line | Q36466678 |
| | Palmatine, a protoberberine alkaloid, inhibits both Ca(2+)- and cAMP-activated Cl(-) secretion in isolated rat distal colon | Q36510073 |
| | Quaternary protoberberine alkaloids. | Q36655345 |
| | DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action | Q36995698 |
| | Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding | Q37077372 |
| | DNA relaxation and cleavage assays to study topoisomerase I inhibitors | Q38297991 |
| | Controlling nucleic acid secondary structure by intercalation: effects of DNA strand length on coralyne-driven duplex disproportionation | Q38352103 |
| | Mode of binding of the cytotoxic alkaloid berberine with the double helix oligonucleotide d(AAGAATTCTT)(2). | Q38358485 |
| | Biophysical aspects and biological implications of the interaction of benzophenanthridine alkaloids with DNA. | Q39310190 |
| | Complete disproportionation of duplex poly(dT)*poly(dA) into triplex poly(dT)*poly(dA)*poly(dT) and poly(dA) by coralyne | Q39530904 |
| | Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model | Q39869955 |
| | Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion | Q39896892 |
| | Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway | Q39955673 |
| | Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines | Q40017585 |
| | DNA Modification and Cancer | Q40101110 |
| | 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA. | Q40118819 |
| | Aurintricarboxylic acid inhibits protein synthesis independent, sanguinarine-induced apoptosis and oncosis. | Q40157960 |
| | Effect of berberine on barrier function in a human retinal pigment epithelial cell line | Q40172059 |
| | Berberine alters the processing of Alzheimer's amyloid precursor protein to decrease Abeta secretion | Q40204649 |
| | Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. | Q40218653 |
| | The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms | Q40248401 |
| | Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine | Q40266596 |
| | The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding. A possible mechanism for its antiproliferative activity. | Q40285367 |
| | Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. | Q40334903 |
| | Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells. | Q40361126 |
| | Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine | Q40542858 |
| | Effects of berberine on glucose metabolism in vitro | Q40693802 |
| | Plasma membrane Ca2+ release-activated Ca2+ channels with a high selectivity for Ca2+ identified by patch-clamp recording in rat liver cells | Q40815484 |
| | Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation | Q41075262 |
| | Cytotoxicity of sanguinarine chloride to cultured human cells from oral tissue | Q41193554 |
| | Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons. | Q41193737 |
| | Cytotoxicity and DNA binding properties of the plant alkaloid burasaine | Q41464623 |
| | Biochemical effects of berberine | Q41606032 |
| | Suppression of angiogenesis by the plant alkaloid, sanguinarine | Q42459696 |
| | Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte. | Q42832329 |
| | Phototoxic and photochemical properties of sanguinarine | Q42984095 |
| | Interaction of isoquinoline alkaloids with polymorphic DNA structures | Q43272644 |
| | Interaction of isoquinoline alkaloids with an RNA triplex: structural and thermodynamic studies of berberine, palmatine, and coralyne binding to poly(U).poly(A)(*)poly(U). | Q43276637 |
| | Ca(2+)-activated K+ channel is present in guinea-pig but lacking in rat hepatocytes | Q43489885 |
| | Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions | Q43504042 |
| P433 | issue | 6 | |
| P304 | page(s) | 821-862 | |
| P577 | publication date | 2010-01-14 | |
| P1433 | published in | Medicinal Research Reviews | Q2436033 |
| P1476 | title | Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design | |
| P478 | volume | 31 | |