The role of testosterone in the etiology and treatment of obesity, the metabolic syndrome, and diabetes mellitus type 2.

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The role of testosterone in the etiology and treatment of obesity, the metabolic syndrome, and diabetes mellitus type 2. is …
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P356DOI10.1155/2011/471584
P932PMC publication ID2931403
P698PubMed publication ID20847893
P5875ResearchGate publication ID46289067

P2093author name stringFarid Saad
Louis J Gooren
P2860cites workThe effect of testosterone supplement on insulin sensitivity, glucose effectiveness, and acute insulin response after glucose load in male type 2 diabetics.Q46850554
Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapyQ46875718
Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population StudyQ46881122
Insulin sensitivity during combined androgen blockade for prostate cancerQ46909972
Testosterone replacement therapy and prostate cancerQ46913725
Hypertension screening of 1 million Americans. Community Hypertension Evaluation Clinic (CHEC) program, 1973 through 1975Q46918551
Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men.Q46947824
A critical evaluation of simple methods for the estimation of free testosterone in serum.Q49081910
The Dark Side of Testosterone Deficiency: II. Type 2 Diabetes and Insulin ResistanceQ22305845
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)Q27860959
Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiencyQ28179470
The decline of androgen levels in elderly men and its clinical and therapeutic implicationsQ28251483
Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapyQ28258997
Testosterone deficiency, insulin resistance and the metabolic syndromeQ28262608
Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men. MRFIT Research Group. Multiple Risk Factor Intervention Trial.Q51035704
Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism.Q51464753
The age related decrease in testosterone is significantly exacerbated in obese men with the metabolic syndrome. What are the implications for the relatively high incidence of erectile dysfunction observed in these men?Q51490671
Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature.Q52719647
Rapidly shifting concepts regarding androgens and prostate cancer.Q54968711
Assimilation of triglycerides in subcutaneous and intraabdominal adipose tissues in vivo in men: effects of testosterone.Q55066612
Dramatic rise in prostate-specific antigen after androgen replacement in a hypogonadal man with occult adenocarcinoma of the prostate.Q64916759
Effects of testosterone supplementation in the aging maleQ67557606
Adipose tissue distribution and functionQ67864882
Longitudinal evaluation of serum androgen levels in men with and without prostate cancerQ71700347
Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadismQ71857797
Development of prostate cancer after pituitary dysfunction: a report of 8 patientsQ73249755
Decreased androgen levels in massively obese men may be associated with impaired function of the gonadostatQ73318718
Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participantsQ73821554
Using quantitative CT to assess adipose distribution in adult men with acquired hypogonadismQ74146698
The association between obesity and the diagnosis of androgen deficiency in symptomatic ageing menQ79395871
The relative contributions of aging, health, and lifestyle factors to serum testosterone decline in menQ79407772
Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapyQ79446008
Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III)Q79678541
The effect of changes in adiposity on testosterone levels in older men: longitudinal results from the Massachusetts Male Aging StudyQ80129104
Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendationsQ81908673
Sex differences in regional body fat distribution from pre- to postpubertyQ84857350
Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men.Q45267265
Low serum testosterone and mortality in male veteransQ45332648
Regional obesity and risk of cardiovascular disease; the Framingham StudyQ45754192
Lower testosterone levels predict incident stroke and transient ischemic attack in older men.Q45926620
Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone.Q45939568
Improvement of the metabolic syndrome and of non-alcoholic liver steatosis upon treatment of hypogonadal elderly men with parenteral testosterone undecanoate.Q45995127
Testosterone and obesity in men under the age of 40 yearsQ46100643
Risk of new-onset diabetes mellitus and worsening glycaemic variables for established diabetes in men undergoing androgen-deprivation therapy for prostate cancerQ46150022
Androgen receptor CAG repeat polymorphism is associated with serum testosterone levels, obesity and serum leptin in men with type 2 diabetesQ46355385
Investigation, treatment and monitoring of late-onset hypogonadism in males. ISA, ISSAM, and EAU recommendationsQ46541677
Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.Q46570705
Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip.Q46595277
Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging StudyQ46757585
Prevalence of overweight and obesity in the United States, 1999-2004Q28305811
The metabolic syndromeQ29616309
Alterations in growth and body composition during puberty: III. Influence of maturation, gender, body composition, fat distribution, aerobic fitness, and energy expenditure on nocturnal growth hormone releaseQ30472079
Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysisQ33222142
The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesityQ33550783
The metabolic syndrome--a neuroendocrine disorder?Q33964740
Endogenous sex hormones in men aged 40-80 yearsQ33974189
Improvement of sexual function in men with late-onset hypogonadism treated with testosterone onlyQ34003029
Androgen replacement therapy in the aging male--a critical evaluationQ34277156
Hormones and prostate cancer: what's next?Q34393202
Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factorsQ34457503
Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysisQ34502187
Androgen-replacement therapy depresses the ex vivo production of inflammatory cytokines by circulating antigen-presenting cells in aging type-2 diabetic men with partial androgen deficiencyQ34531591
Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definitionQ34545044
Effect of puberty on body compositionQ34912405
The role of testosterone in the metabolic syndrome: a reviewQ34981185
The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic processQ34982639
Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; InternatQ35006662
Testosterone therapy and prostate carcinomaQ35009920
Prevalence of hypogonadism in males aged at least 45 years: the HIM studyQ35037892
Risks of testosterone-replacement therapy and recommendations for monitoringQ35641798
Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease riskQ35794460
Androgen replacement after curative radical prostatectomy for prostate cancer in hypogonadal men.Q35862931
Direct effects of sex steroid hormones on adipose tissues and obesityQ35905509
Testosterone therapy in the ageing male: what about the prostate?Q35947307
Testosterone treatment for the aging man: the controversyQ35947451
Low testosterone is associated with decreased function and increased mortality risk: a preliminary study of men in a geriatric rehabilitation unitQ35967464
The development of prostate cancer despite late onset androgen deficiency.Q36275532
Low serum testosterone and mortality in older men.Q36360750
Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guidelineQ36486899
The metabolic syndrome, depression, and cardiovascular disease: interrelated conditions that share pathophysiologic mechanismsQ36537386
Elevated body mass index and mortality risk in the elderlyQ36703092
Body composition, metabolic syndrome and testosterone in ageing men.Q36842367
Testosterone concentration in young patients with diabetesQ36906249
Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groupsQ36938377
Sexual dimorphism of body compositionQ36944272
Androgen deficiency, diabetes, and the metabolic syndrome in men.Q36973087
Androgens and body fat distributionQ36975178
Role of body fat distribution and the metabolic complications of obesityQ36979749
Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) studyQ37105445
Statin therapy is associated with lower total but not bioavailable or free testosterone in men with type 2 diabetesQ37139412
Investigation, treatment and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA and ASA recommendationsQ37310024
Prediction of metabolic syndrome by low serum testosterone levels in men: results from the study of health in PomeraniaQ37317410
Testosterone in obesity, metabolic syndrome and type 2 diabetesQ37326209
Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapyQ37372781
The dark side of testosterone deficiency: III. Cardiovascular diseaseQ37431142
Testosterone and prostate cancer: revisiting old paradigmsQ37450000
Obesity and testicular functionQ37525109
The role of testosterone in type 2 diabetes and metabolic syndrome in men.Q37686143
Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trialQ38402163
The efficacy and safety of testosterone undecanoate (Nebido(®)) in testosterone deficiency syndrome in Korean: a multicenter prospective studyQ38487266
Testosterone replacement in prostate cancer survivors with hypogonadal symptomsQ39295915
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged menQ39513420
Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trialsQ39738952
The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert ConsultationQ39919146
Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging studyQ40760488
Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levelsQ42478739
Prostate cancer after exogenous testosterone treatment for impotenceQ42550086
Effect of a sequential training programme on inflammatory, prothrombotic and vascular remodelling biomarkers in hypertensive overweight patients with or without metabolic syndromeQ43278811
Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: the Health In Men StudyQ43297274
Effects of GH and/or sex steroid administration on abdominal subcutaneous and visceral fat in healthy aged women and men.Q43705618
Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo studyQ43843236
Effects of androgen deprivation on glycaemic control and on cardiovascular biochemical risk factors in men with advanced prostate cancer with diabetesQ43959465
Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S.Q44470244
Aging, androgens, and the metabolic syndrome in a longitudinal study of agingQ44525492
A 5-year follow-up study of disease incidence in men with an abnormal hormone patternQ44585247
Sex hormones, inflammation and the metabolic syndrome: a population-based studyQ44670623
Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men.Q44685104
Changes in fat and lean body mass during androgen-deprivation therapy for prostate cancerQ44836371
Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.Q44865591
Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trialQ45071179
Waist circumference and testosterone levels in community dwelling men. The Tromsø studyQ45087781
Effects of androgen therapy on adipose tissue and metabolism in older men.Q45096562
Testosterone replacement therapy after primary treatment for prostate cancerQ45219185
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectobesityQ12174
metabolic syndromeQ657193
testosteroneQ1318776
type 2 diabetesQ3025883
testosteroneQ27863114
P304page(s)683-685
P577publication date2010-08-10
P1433published inJournal of ObesityQ26842383
P1476titleThe role of testosterone in the etiology and treatment of obesity, the metabolic syndrome, and diabetes mellitus type 2.
P478volume2011

Reverse relations

cites work (P2860)
Q43244910A 47,X,+t(X;X)(p22.3;p22.3)del(X)(p11.23q11.2),Y Klinefelter variant with morbid obesity
Q41573277A Comparative Study of Australian and New Zealand Male and Female Nurses' Health: A Sex Comparison and Gender Analysis.
Q64260365A Short Study Exploring the Effect of the Glycaemic Index of the Diet on Energy intake and Salivary Steroid Hormones
Q36370472A cross-sectional study of the association of age, race and ethnicity, and body mass index with sex steroid hormone marker profiles among men in the National Health and Nutrition Examination Survey (NHANES III)
Q35573457Acute testosterone deprivation reduces insulin sensitivity in men
Q36697884An overview of the contribution of fatness and fitness factors, and the role of exercise, in the formation of health status for individuals who are overweight
Q37851063Androgen deficiency in heart failure
Q57828021Benefits and Consequences of Testosterone Replacement Therapy: A Review
Q35682481Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library
Q35810628Connecting the Lines between Hypogonadism and Atherosclerosis
Q35624509Diagnosis and treatment of sexual dysfunctions in late-onset hypogonadism
Q24288837Diet, exercise or diet with exercise: comparing the effectiveness of treatment options for weight-loss and changes in fitness for adults (18-65 years old) who are overfat, or obese; systematic review and meta-analysis
Q38071006Do we need anti-obesity drugs?
Q34063853Effect of 12 months of testosterone replacement therapy on metabolic syndrome components in hypogonadal men: data from the Testim Registry in the US (TRiUS).
Q59813297Effects of testosterone undecanoate replacement and withdrawal on cardio-metabolic, hormonal and body composition outcomes in severely obese hypogonadal men: a pilot study
Q89161029Endocrine treatment of aging transgender people
Q35994260Hormonal determinants of the severity of andropausal and depressive symptoms in middle-aged and elderly men with prediabetes
Q40698744Is testosterone deficiency a possible risk factor for priapism associated with sickle-cell disease?
Q34516774Molecular sex differences in human serum
Q37502104Multiple hormonal dysregulation as determinant of low physical performance and mobility in older persons.
Q35750773Nature of fatty acids in high fat diets differentially delineates obesity-linked metabolic syndrome components in male and female C57BL/6J mice
Q49971559Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men.
Q30403762Obese mice have increased morbidity and mortality compared to non-obese mice during infection with the 2009 pandemic H1N1 influenza virus
Q21256713Randomized control trial to evaluate the effects of acute testosterone administration in men on muscle mass, strength, and physical function following ACL reconstructive surgery: rationale, design, methods
Q91768365Relationship of transcriptional markers to Leydig cell number in the mouse testis
Q39432023Testosterone replacement therapy does not promote priapism in hypogonadal men with sickle cell disease: 12-month safety report
Q37306092The effect of obesity and components of metabolic syndrome on urinary and sexual functions in Saudi men
Q48685313The inter-relational effect of metabolic syndrome and sexual dysfunction on hypogonadism in type II diabetic men.
Q48072729The practical management of testosterone deficiency in men.
Q36796228The role of androgens and estrogens on healthy aging and longevity
Q38057355The role of obesity and type 2 diabetes mellitus in the development of male obesity-associated secondary hypogonadism
Q34108216The role of the urologist in the prevention and early detection of cardiovascular disease
Q36932044What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?

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