Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models

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Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1111/J.1476-5381.2010.00721.X
P932PMC publication ID2931552
P698PubMed publication ID20590561
P5875ResearchGate publication ID44887510

P50authorTiziana RubinoQ56613336
P2093author name stringMatthew N Hill
Daniel T Malone
P2860cites workCannabis and psychiatric disorders: it is not only addictionQ22242611
Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young peopleQ24558606
Cannabinoid receptor localization in brainQ24558751
Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathologyQ24602238
CB2 receptors in the brain: role in central immune functionQ24643895
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterningQ24650912
High-potency cannabis and the risk of psychosisQ24651025
Brain development during childhood and adolescence: a longitudinal MRI studyQ28144698
Role of endogenous cannabinoids in synaptic signalingQ28185075
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in reviewQ28215767
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic reviewQ28238516
Structure of a cannabinoid receptor and functional expression of the cloned cDNAQ28240076
Causal association between cannabis and psychosis: examination of the evidenceQ28241735
Adverse health effects of non-medical cannabis useQ28261715
Identification and functional characterization of brainstem cannabinoid CB2 receptorsQ28276972
Cannabis and schizophrenia. A longitudinal study of Swedish conscriptsQ28283322
Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophreniaQ28285577
Molecular characterization of a peripheral receptor for cannabinoidsQ28298338
Enzymatic pathways that regulate endocannabinoid signaling in the nervous systemQ28390932
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic studyQ29615905
The adolescent brain and age-related behavioral manifestationsQ29618654
Determination and characterization of a cannabinoid receptor in rat brainQ29618888
The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for PsychosisQ30047193
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brainQ30047898
Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophreniaQ30478274
Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapiesQ30484459
Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in ratsQ30489165
Development of cannabinoid 1 receptor protein and messenger RNA in monkey dorsolateral prefrontal cortexQ30494037
Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in ratsQ33435013
The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophreniaQ33679799
Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the "two hit hypothesis".Q33813156
Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use.Q43581230
Autoradiographic study of pre- and postnatal distribution of cannabinoid receptors in human brainQ43798328
The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female ratsQ43908958
Delta(9)-tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis studyQ44182591
Early-onset cannabis use and cognitive deficits: what is the nature of the association?Q44360031
Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain.Q44444709
Testing hypotheses about the relationship between cannabis use and psychosisQ44487800
Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult ratsQ44530990
Reduced binocular depth inversion in regular cannabis usersQ44574413
Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophreniaQ44748286
Cannabis use and psychosis: a longitudinal population-based study.Q44820509
Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophreniaQ44865127
Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatumQ44906750
Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptomsQ45049153
Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult ratsQ45176520
Altered brain tissue composition in heavy marijuana usersQ45193430
Trends in cannabis use prior to first presentation with schizophrenia, in South-East London between 1965 and 1999.Q45247994
Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthoodQ45779424
Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia.Q46013619
Cannabis use in children and adolescents with first episode psychosis: influence on psychopathology and short-term outcome (CAFEPS study).Q46019528
The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortexQ46041526
Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosisQ46066555
Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats.Q46179690
Cognitive and psychomotor effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg delta-9-tetrahydrocannabinol (THC).Q46188729
Marijuana: use among young males and health outcomesQ46224428
Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophreniaQ46370479
Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid systemQ46455764
The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated ratsQ46688133
Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonist WIN 55,212-2.Q46691546
Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.Q46825379
Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerolQ33900859
Adolescent cannabis use, psychosis and catechol-O-methyltransferase genotype in African Americans and CaucasiansQ33925455
Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophreniaQ33932087
Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort studyQ33962711
Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drugQ33995048
Hippocampal abnormalities and memory deficits: new evidence of a strong pathophysiological link in schizophreniaQ34002498
Schizophrenia as a disorder of neurodevelopmentQ34132313
Nonpsychotropic cannabinoid receptors regulate microglial cell migration.Q34179008
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptorQ34245130
Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interactionQ34415424
Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in miceQ34438163
CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms.Q34504178
Effects of frequent marijuana use on brain tissue volume and compositionQ34507628
Brain morphological changes and early marijuana use: a magnetic resonance and positron emission tomography studyQ34508346
Cannabis, vulnerability, and the onset of schizophrenia: an epidemiological perspectiveQ34509505
Tests of causal linkages between cannabis use and psychotic symptomsQ34555395
Cannabis use and psychotic disorders: an updateQ34555939
Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabisQ34589855
Regional brain abnormalities associated with long-term heavy cannabis use.Q34592700
Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depressionQ34609936
Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.Q34708753
Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzymeQ34721779
Stress, sensitive periods and maturational events in adolescent depressionQ34760313
Cannabinoid receptors: where they are and what they do.Q34772274
Youth risk behavior surveillance--United States, 2007.Q34784855
Effects of cannabis use on outcomes of psychotic disorders: systematic reviewQ34870543
A preliminary DTI study showing no brain structural change associated with adolescent cannabis use.Q34880461
Role of cannabis and endocannabinoids in the genesis of schizophreniaQ34993855
Brain cannabinoid CB2 receptor in schizophreniaQ35014134
Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetryQ35677987
Psychological and social sequelae of cannabis and other illicit drug use by young people: a systematic review of longitudinal, general population studiesQ35774562
Adolescent brain development: a period of vulnerabilities and opportunities. Keynote addressQ35835571
How antipsychotics become anti-"psychotic"--from dopamine to salience to psychosisQ35847108
Is the party over? Cannabis and juvenile psychiatric disorder: the past 10 yearsQ35894468
Endocannabinoid signaling system and brain reward: emphasis on dopamineQ36152336
First-episode psychosis: psychopathology, quality of life, and functional outcomeQ36188449
Impact of substance use on the onset and course of early psychosisQ36273889
Cannabinoids and prefrontal cortical function: insights from preclinical studiesQ36436004
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral dataQ36441017
Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?Q36517227
The emerging functions of endocannabinoid signaling during CNS development.Q36707633
Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescentsQ36744255
Relationship of catechol-O-methyltransferase to schizophrenia and its correlates: evidence for associations and complex interactionsQ36965866
Endocannabinoid functions controlling neuronal specification during brain developmentQ37131370
Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regionsQ37136294
Cannabis, cannabinoids and schizophrenia: integration of the evidenceQ37160448
The cognitive neuroscience of memory function and dysfunction in schizophreniaQ37169856
Wiring and firing neuronal networks: endocannabinoids take center stageQ37272835
Altered white matter microstructure in adolescent substance usersQ37325687
Prefrontal cortex morphometry in abstinent adolescent marijuana users: subtle gender effectsQ37341421
Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effectsQ37349953
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.Q38322450
Prevalence and correlates of past-year substance use, abuse, and dependence in a suburban community sample of high-school studentsQ39674159
Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective studyQ39680990
Hardwiring the brain: endocannabinoids shape neuronal connectivityQ39798626
Changing incidence of psychotic disorders among the young in ZurichQ40193848
Cannabis and schizophrenia: model projections of the impact of the rise in cannabis use on historical and future trends in schizophrenia in England and WalesQ40233735
Reduced binocular depth inversion as an indicator of cannabis-induced censorship impairmentQ41132462
Preferential limbic expression of the cannabinoid receptor mRNA in the human fetal brainQ42440191
Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatmentQ42446801
Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousnessQ43406707
Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociceptionQ43511723
The association between early cannabis use and psychotic-like experiences in a community adolescent sampleQ43534322
Localization of mRNA expression and activation of signal transduction mechanisms for cannabinoid receptor in rat brain during fetal development.Q47812684
Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.Q48063516
Adolescent rats find repeated Delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposureQ48131076
Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidineQ48286778
Presence of cannabinoid binding sites in the brain from early postnatal agesQ48335987
An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognitionQ48435557
Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in ratsQ48446296
The effects of an early stressful life event on sensorimotor gating in adult rats.Q48468623
Recent-onset schizophrenia and adolescent cannabis use: MRI evidence for structural hyperconnectivity?Q48508827
Increased cannabinoid receptor density in the posterior cingulate cortex in schizophreniaQ48532654
The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesionQ48552353
Ultrastructural localization of neuronal brain CB2 cannabinoid receptors.Q48837860
Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging studyQ48881901
Neuroimaging of marijuana smokers during inhibitory processing: a pilot investigationQ48952162
Different effects of nabilone and cannabidiol on binocular depth inversion in Man.Q51080370
Sex differences in the effects of delta9-tetrahydrocannabinol on spatial learning in adolescent and adult rats.Q51739846
Long-term effects of developmental PCP administration on sensorimotor gating in male and female rats.Q51779948
Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics.Q51891740
Cannabis use and brain structural alterations in first episode schizophrenia--a region of interest, voxel based morphometric study.Q51894564
Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use.Q51902545
Early adolescent cannabis exposure and positive and negative dimensions of psychosis.Q51937432
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles.Q51982139
A community survey of adverse effects of cannabis use.Q52006749
Psychotic reactions following cannabis use in East Indians.Q52117018
The ontogeny of cannabinoid receptors in the brain of postnatal and aging rats.Q52211667
Cannabis and psychosis: two kinds of limitations which attach to epidemiological researchQ52286020
The disruption of prepulse inhibition by social isolation in the Wistar rat: how robust is the effect?Q52530694
A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1Q55970558
Symptoms of schizotypy precede cannabis useQ56768431
Association of cannabis use with prodromal symptoms of psychosis in adolescenceQ56906218
Cannabis use and age of diagnosis of schizophreniaQ57602685
Schizotypy and psychosis-like experiences from recreational cannabis in a non-clinical sampleQ59599152
Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system.Q64996366
Cannabis induced psychosisQ71048435
Elevated endogenous cannabinoids in schizophreniaQ73029596
The role of endogenous sensitization in the pathophysiology of schizophrenia: implications from recent brain imaging studiesQ73553209
A clinical and metabolic study of acute intoxication with Cannabis sativa and its role in the model psychosesQ78517764
Effects of cannabis and psychosis vulnerability in daily life: an experience sampling test studyQ78822220
A population based elaboration of the role of age of onset on the course of schizophreniaQ80235261
Endogenous cannabinoids: structure and metabolismQ95801320
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectepidemiologyQ133805
psychosisQ170082
teenagerQ1492760
P304page(s)511-522
P577publication date2010-06-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleAdolescent cannabis use and psychosis: epidemiology and neurodevelopmental models
P478volume160

Reverse relations

cites work (P2860)
Q34304922A comparative, developmental, and clinical perspective of neurobehavioral sexual dimorphisms
Q40549028Accumulated environmental risk determining age at schizophrenia onset: a deep phenotyping-based study
Q58734455Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood
Q50063042Adolescent synthetic cannabinoid exposure produces enduring changes in dopamine neuron activity in a rodent model of schizophrenia susceptibility
Q89457514Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling
Q51819710Affective disorders and anxiety disorders predict the risk of drug harmful use and dependence.
Q36064385Age-Related Differences and Heritability of the Perisylvian Language Networks
Q28650412Associations of cannabis and cigarette use with psychotic experiences at age 18: findings from the Avon Longitudinal Study of Parents and Children
Q34251969Blurred boundaries: the therapeutics and politics of medical marijuana
Q35536880Brain volume in male patients with recent onset schizophrenia with and without cannabis use disorders.
Q39664119Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?
Q37147730Cannabis Use and Associated Harms among Schizophrenia Patients in a Nigerian Clinical Setting: A Case-Control Study
Q47559437Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells
Q27024404Cannabis and psychosis: Neurobiology
Q34634045Cannabis use and cognitive dysfunction
Q47126115Chronic Adolescent Δ9-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment
Q42428524Clearing the smoke: what do we know about adolescent cannabis use and schizophrenia?
Q38124448Comorbid substance use disorder in schizophrenia: a selective overview of neurobiological and cognitive underpinnings
Q35229933Comorbid substance use disorders in schizophrenia: a latent class approach
Q35609139Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470.
Q58099901Concordance between the diagnostic guidelines for alcohol and cannabis use disorders in the draft ICD-11 and other classification systems: Analysis of data from the WHO's World Mental Health Surveys
Q38916455Consequences of adolescent use of alcohol and other drugs: Studies using rodent models
Q60499987Consumo de cannabis y neurodesarrollo: ¿por qué son relevantes las diferencias de género?
Q34322915Daily use, especially of high-potency cannabis, drives the earlier onset of psychosis in cannabis users
Q34350080Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex
Q30366949Does Cannabis Cause, Exacerbate or Ameliorate Psychiatric Disorders? An Oversimplified Debate Discussed
Q38945304Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex?
Q36417706Drug discovery strategies that focus on the endocannabinoid signaling system in psychiatric disease
Q36672926Effects of cannabis on neurocognitive functioning: recent advances, neurodevelopmental influences, and sex differences
Q37090161Elucidating cannabinoid biology in zebrafish (Danio rerio).
Q34269194Emerging adult age status predicts poor buprenorphine treatment retention.
Q36679940Epigenetic Effects of Cannabis Exposure
Q38262458Families parenting adolescents with substance abuse--recovering the mother's voice: a narrative literature review
Q35063812Functional activation and effective connectivity differences in adolescent marijuana users performing a simulated gambling task
Q38784874High times for cannabis: Epigenetic imprint and its legacy on brain and behavior
Q36636731Impulsivity, attention, memory, and decision-making among adolescent marijuana users.
Q36975926Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans
Q37512670Marijuana Compounds: A Nonconventional Approach to Parkinson's Disease Therapy.
Q47569059Mothers' Experiences of Supporting Adolescent Children Through Long-Term Treatment for Substance Use Disorder
Q35019147Multimodal neuroimaging of frontal white matter microstructure in early phase schizophrenia: the impact of early adolescent cannabis use
Q37705771Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation.
Q34378233Pathways from cannabis to psychosis: a review of the evidence
Q99413706Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats
Q39480548Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder
Q50990610Prenatal marijuana exposure, age of marijuana initiation, and the development of psychotic symptoms in young adults.
Q37048662Recreational marijuana use impacts white matter integrity and subcortical (but not cortical) morphometry.
Q30467877Reversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice.
Q38697025Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia.
Q52590817Sex and age differences in risk factors of marijuana involvement during adolescence.
Q28534825Sex-dependent psychoneuroendocrine effects of THC and MDMA in an animal model of adolescent drug consumption
Q37131057Structural brain alterations associated with schizophrenia preceded by conduct disorder: a common and distinct subtype of schizophrenia?
Q47920779THC Treatment Alters Glutamate Receptor Gene Expression in Human Stem Cell-Derived Neurons
Q58101634The Effect of Age of Initiation of Cannabis Use on Psychosis, Depression, and Anxiety among Youth under 25 Years
Q56970483The Initiation of Cannabis Use in Adolescence is Predicted by Sex-Specific Psychosocial and Neurobiological Features
Q35563620The Medicinal Cannabis Treatment Agreement: Providing Information to Chronic Pain Patients Through a Written Document
Q37946259The dynorphin/κ-opioid receptor system and its role in psychiatric disorders
Q35597394The effects of mental health symptoms and marijuana expectancies on marijuana use and consequences among at-risk adolescents
Q37888955The endocannabinoid system in critical neurodevelopmental periods: sex differences and neuropsychiatric implications.
Q24601890The endocannabinoid system, cannabinoids, and pain
Q34447140The impact of adolescent cannabis use, mood disorder and lack of education on attempted suicide in young adulthood
Q47405586The persistence of the association between adolescent cannabis use and common mental disorders into young adulthood
Q34326515The pharmacologic and clinical effects of medical cannabis.
Q24620262Themed issue: cannabinoids
Q36217627Trajectories of marijuana use from adolescence into adulthood: Environmental and individual correlates
Q39181416Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis