Osteoarthritis and cartilage: the role of cytokines

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Osteoarthritis and cartilage: the role of cytokines is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1007258940
P356DOI10.1007/S11926-000-0021-Y
P698PubMed publication ID11123098

P2093author name stringGoldring MB
P2860cites workPurification and cloning of aggrecanase-1: a member of the ADAMTS family of proteinsQ22009926
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The rationale for the current boom in anti-TNFalpha treatment. Is there an effective means to define therapeutic targets for drugs that provide all the benefits of anti-TNFalpha and minimise hazards?Q33782321
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Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis.Q35549401
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Cytokines in osteoarthritis: mediators or markers of joint destruction?Q41133438
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Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signalling pathways in human OA synovial fibroblastsQ42481831
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Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse modelQ43854219
Gene therapy for rheumatic diseasesQ45855770
Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction.Q45862676
In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapyQ45882179
Regulatory role of interleukin 10 in joint inflammation and cartilage destruction in murine streptococcal cell wall (SCW) arthritis. More therapeutic benefit with IL-4/IL-10 combination therapy than with IL-10 treatment aloneQ47996975
Comparative study of serum and synovial fluid interleukin-11 levels in patients with various arthritides.Q52228131
Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathiesQ71339960
Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritisQ71503443
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritisQ73374754
The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritisQ73414195
Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)Q73574480
Synovial fluid interleukin 6, tumor necrosis factor, and nitric oxide values in dogs with osteoarthritis secondary to cranial cruciate ligament ruptureQ73669005
Low-level production of interleukin-13 in synovial fluid and tissue from patients with arthritisQ73820790
Articular cartilage repair and transplantationQ77093059
Inhibition of extracellular matrix-degrading endopeptidases: problems, comments, and hypothesesQ77477157
The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cellsQ77755017
IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responsesQ77899699
Relationship of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover: analyses of synovial fluid from patients with osteoarthritisQ77909427
Reexpression of type IIA procollagen by adult articular chondrocytes in osteoarthritic cartilageQ77993335
The regulation of MMPs and TIMPs in cartilage turnoverQ78027218
Effects of IL-6 and its soluble receptor on proteoglycan synthesis and NO release by human articular chondrocytes: comparison with IL-1. Modulation by dexamethasoneQ78074203
Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18Q78124693
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectosteoarthritisQ62736
cartilageQ502730
P304page(s)459-465
P577publication date2000-12-01
P1433published inCurrent Rheumatology ReportsQ23930052
P1476titleOsteoarthritis and cartilage: the role of cytokines
P478volume2

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