Restoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2).

scientific article

Restoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(02)02250-0
P698PubMed publication ID11852074

P2093author name stringPachiyappan Kamarajan
Chuck C-K Chao
Haimei Huang
Nian Kang Sun
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosisQ24313625
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosisQ24316760
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosisQ24318803
Mutations specific to the xeroderma pigmentosum group E Ddb- phenotypeQ24322600
Caspases: the executioners of apoptosisQ24530218
Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding proteinQ24563372
A simplified system for generating recombinant adenovirusesQ24682328
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymeraseQ26778389
Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1Q28143454
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICADQ28258328
Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding proteinQ28271155
Isolation of a cDNA encoding a UV-damaged DNA binding factor defective in xeroderma pigmentosum group E cellsQ28271751
Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNAQ28292106
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin AQ28610837
DNA excision repairQ29618453
Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A.Q32064326
Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.Q33556647
Biochemical pathways of caspase activation during apoptosisQ33804316
Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesisQ33949593
An induced proximity model for caspase-8 activation.Q34065853
Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosisQ34476760
A 127 kDa component of a UV-damaged DNA-binding complex, which is defective in some xeroderma pigmentosum group E patients, is homologous to a slime mold proteinQ34999430
A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cellsQ35864616
Cross-resistance to UV radiation of a cisplatin-resistant human cell line: overexpression of cellular factors that recognize UV-modified DNAQ36688531
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.Q36697936
A constitutive damage-specific DNA-binding protein is synthesized at higher levels in UV-irradiated primate cellsQ36708151
Purification of a HeLa cell nuclear protein that binds selectively to DNA irradiated with ultra-violet lightQ38317444
Purification and characterization of a human protein that binds to damaged DNA.Q38321540
UV damage-specific DNA-binding protein in xeroderma pigmentosum complementation group E.Q38336006
p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activityQ39575414
Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell lineQ40779227
Isolation and analysis of components of CD95 (APO-1/Fas) death-inducing signaling complexQ40962126
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosisQ41204766
Apparent alterations in the early stage of excision repair of UV-induced DNA damages in a HeLa mutant cell line that is resistant to genotoxic stressesQ41532369
Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.Q41731658
Damage-recognition proteins as a potential indicator of DNA-damage-mediated sensitivity or resistance of human cells to ultraviolet radiationQ41791031
Identification of inducible damage-recognition proteins that are overexpressed in HeLa cells resistant to cis-diamminedichloroplatinum (II).Q41881603
Biochemical heterogeneity in xeroderma pigmentosum complementation group EQ42026787
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).Q43806672
Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.Q54483602
A DNA binding protein from human placenta specific for ultraviolet damaged DNAQ67460728
P433issue1-3
P407language of work or nameEnglishQ1860
P304page(s)168-172
P577publication date2002-02-01
P1433published inFEBS LettersQ1388051
P1476titleRestoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2).
P478volume512

Reverse relations

cites work (P2860)
Q48131232DICER- and MMSET-catalyzed H4K20me2 recruits the nucleotide excision repair factor XPA to DNA damage sites
Q38347542DNA damage-binding proteins and heterogeneous nuclear ribonucleoprotein A1 function as constitutive KCS element components of the interferon-inducible RNA-dependent protein kinase promoter
Q33828372Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila
Q39383957Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28-MDM2-p53 complexes and by preventing the ubiquitination and degradation of p53.
Q40129773Involvement of reactive oxygen species in multidrug resistance of a vincristine-selected lymphoblastoma
Q101217368The draft genome of the blood pheasant (Ithaginis cruentus): Phylogeny and high-altitude adaptation
Q38335681Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

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