VHS domain -- a longshoreman of vesicle lines.

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VHS domain -- a longshoreman of vesicle lines. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0014-5793(01)03287-2
P698PubMed publication ID11911875

P50authorOlli LohiQ56480958
Yuxin MaoQ77815229
P2093author name stringVeli Pekka Lehto
Anssi Poussu
Florante Quiocho
P2860cites workPossible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokinesQ22010172
Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domainQ28593533
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiaeQ29620184
A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptorsQ30175258
VHS domain marks a group of proteins involved in endocytosis and vesicular traffickingQ30175928
EAST, an epidermal growth factor receptor- and Eps15-associated protein with Src homology 3 and tyrosine-based activation motif domainsQ30176098
A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systemsQ33951379
Molecular links between endocytosis and the actin cytoskeleton.Q34023649
Hrs and hbp: possible regulators of endocytosis and exocytosisQ34177941
Function of Hrs in endocytic trafficking and signallingQ34332402
A new ticket for entry into budding vesicles-ubiquitinQ34365247
A selective transport route from Golgi to late endosomes that requires the yeast GGA proteinsQ36342591
Yeast Gga coat proteins function with clathrin in Golgi to endosome transportQ37073871
EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibersQ40997372
Involvement of hrs binding protein in IgE receptor-triggered exocytosis in RBL-2H3 mast cellsQ42834362
Hrs-2 is an ATPase implicated in calcium-regulated secretionQ48053660
Early endosomal localization of hrs requires a sequence within the proline- and glutamine-rich region but not the FYVE fingerQ73977892
A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-GolgiQ22253480
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting proteinQ24291185
Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domainsQ24291292
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory SmadsQ24291512
Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growthQ24315648
Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAMQ24318617
A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolutionQ24563263
SMART, a simple modular architecture research tool: identification of signaling domainsQ24597380
Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZQ24669673
Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machineryQ24672800
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosomeQ24685974
GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complexQ24685976
Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transductionQ27621560
Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranesQ27627053
A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosisQ27630407
Three-dimensional structure of the armadillo repeat region of beta-cateninQ27743283
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domainsQ27933286
The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathwaysQ27936688
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPQ28138440
Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptorQ28139720
Yeast GGA proteins interact with GTP-bound Arf and facilitate transport through the GolgiQ28140794
STAM2, a new member of the STAM family, binding to the Janus kinasesQ28141037
Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synerginQ28144526
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domainsQ28145827
Sorting of mannose 6-phosphate receptors mediated by the GGAsQ28198872
Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptorQ28198896
Topological characteristics of helical repeat proteinsQ28199033
The GGAs promote ARF-dependent recruitment of clathrin to the TGNQ28212201
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc inductionQ28236871
Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomesQ28245945
FYVE fingers bind PtdIns(3)PQ28279043
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE fingerQ28289331
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)19-23
P577publication date2002-02-01
P1433published inFEBS LettersQ1388051
P1476titleVHS domain -- a longshoreman of vesicle lines
P478volume513

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cites work (P2860)
Q47304126A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor
Q24307896Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles
Q31096789Cloning and characterization of cellular senescence-associated genes in human fibroblasts by suppression subtractive hybridization
Q33287350Comprehensive analysis of co-occurring domain sets in yeast proteins
Q28203579Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains
Q27640585Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocket
Q35800773Cysteine-Rich Atrial Secretory Protein from the Snail Achatina achatina: Purification and Structural Characterization
Q38684233Endocytic membrane trafficking and neurodegenerative disease
Q41066260Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe
Q42254419Evolution and origin of HRS, a protein interacting with Merlin, the Neurofibromatosis 2 gene product.
Q33851657HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition
Q38270400Helping hands for budding prospects: ENTH/ANTH/VHS accessory proteins in endocytosis, vacuolar transport, and secretion
Q24311300Identification of a novel ubiquitin binding site of STAM1 VHS domain by NMR spectroscopy
Q28203894Interaction of the deafness-dystonia protein DDP/TIMM8a with the signal transduction adaptor molecule STAM1
Q34386311Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.
Q28215685Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2
Q35675894Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS
Q24310583Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair
Q30047024Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance
Q27936195Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae
Q30368988Overview of protein structural and functional folds.
Q24320039Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
Q29540749RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template
Q37221683STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking
Q24669647STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif
Q36288988Sequence analysis of Arabidopsis thaliana E/ANTH-domain-containing proteins: membrane tethers of the clathrin-dependent vesicle budding machinery
Q40181995Splice variant of mouse Stam2 mRNA in nervous and muscle tissue contains additional exon with stop codon within region coding for VHS domain
Q35641705Structural basis for inhibition of translation by the tumor suppressor Pdcd4.
Q24305586Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain
Q27701666Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold
Q33983878Study of Arabidopsis thaliana resistome in response to cucumber mosaic virus infection using whole genome microarray
Q64077495Syk and Hrs Regulate TLR3-Mediated Antiviral Response in Murine Astrocytes
Q33304751TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells
Q28277407Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics
Q28209625The ENTH domain
Q41824025The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities
Q24304594The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors
Q45977145The fertility restorer gene, Rf2, for Lead Rice-type cytoplasmic male sterility of rice encodes a mitochondrial glycine-rich protein.
Q24658483Therapeutic targeting of Janus kinases
Q28253040Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes
Q24297958Tom1, a VHS Domain-containing Protein, Interacts with Tollip, Ubiquitin, and Clathrin

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