Gabapentin enacarbil (XP13512/GSK1838262) as an alternative treatment to dopaminergic agents for restless legs syndrome

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Gabapentin enacarbil (XP13512/GSK1838262) as an alternative treatment to dopaminergic agents for restless legs syndrome is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/14656566.2010.494598
P698PubMed publication ID20629607

P2093author name stringClete Kushida
Susan Imamura
P2860cites workEffect of ropinirole on sleep outcomes in patients with restless legs syndrome: meta-analysis of pooled individual patient data from randomized controlled trialsQ33413352
Pathological gambling caused by drugs used to treat Parkinson diseaseQ33988551
Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q.Q34044826
The effect of food with varying fat content on the clinical pharmacokinetics of gabapentin after oral administration of gabapentin enacarbilQ34097242
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transportersQ34321050
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: II. Improved oral bioavailability, dose proportionality, and colonic absorption compared with gabapentin in rats and monkeyQ34321054
Restless legs syndrome prevalence and impact: REST general population studyQ34426489
Prevalence of restless legs syndrome and periodic limb movement disorder in the general populationQ34525455
Autosomal dominant restless legs syndrome maps on chromosome 14q.Q34533932
Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolateQ34564654
A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13.Q34565302
A genetic risk factor for periodic limb movements in sleepQ34651669
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regionsQ34653028
Clinical pharmacokinetics of XP13512, a novel transported prodrug of gabapentinQ34841404
Treatment of restless legs syndrome: an evidence-based review and implications for clinical practiceQ34858059
Accommodating chromosome inversions in linkage analysisQ35015731
Pramipexole for the treatment of restless legs syndromeQ36407375
A randomized, double-blind, placebo-controlled trial of intravenous iron sucrose in restless legs syndromeQ37244788
Comparative placebo-controlled polysomnographic and psychometric studies on the acute effects of gabapentin versus ropinirole in restless legs syndromeQ43202454
Gabapentin enacarbil in restless legs syndrome: a phase 2b, 2-week, randomized, double-blind, placebo-controlled trialQ43294942
Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over studyQ44228579
Augmentation and tolerance with long-term pramipexole treatment of restless legs syndrome (RLS).Q44729978
Long-term treatment of restless legs syndrome with dopamine agonistsQ45056935
Randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS.Q46135857
A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndromeQ48398969
Restless legs syndrome: diagnosis, epidemiology, classification and consequencesQ48479960
Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care studyQ48591904
Restless legs syndrome: a clinical study of 55 patientsQ48701164
Prevalences of periodic limb movement-like and restless legs-like symptoms among Japanese adultsQ48704536
A randomized, double-blind placebo-controlled trial of iron in restless legs syndrome.Q48730830
Clonazepam and vibration in restless legs syndromeQ49076085
Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: results from a multi-center, randomized, active controlled trial.Q53242298
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
gabapentin enacarbilQ5515257
gabapentinQ410352
restless legs syndromeQ916280
P304page(s)1925-1932
P577publication date2010-08-01
P1433published inExpert Opinion on PharmacotherapyQ5421212
P1476titleGabapentin enacarbil (XP13512/GSK1838262) as an alternative treatment to dopaminergic agents for restless legs syndrome
P478volume11

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Q38122149Gabapentin enacarbil: pharmacotherapy of restless legs syndromecites workP2860

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