Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies

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Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1460-9568.2010.07349.X
P932PMC publication ID2955837
P698PubMed publication ID20646055
P5875ResearchGate publication ID45277176

P50authorJosep DalmauQ37828790
P2093author name stringAnkit Jain
Rita J Balice-Gordon
Xiaoyu Peng
Emilia H Moscato
Ethan G Hughes
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Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodiesQ37559509
Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zonesQ37690986
Beyond viruses: clinical profiles and etiologies associated with encephalitisQ37860911
Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat.Q38308644
Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).Q39576197
Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitisQ39961545
Characterization of ganglionic acetylcholine receptor autoantibodiesQ39981430
The action of Lambert-Eaton myasthenic syndrome immunoglobulin G on cloned human voltage-gated calcium channelsQ40733834
Characterization of glutamate binding sites in receptors assembled from transfected NMDA receptor subunits.Q41180674
Lambert-Eaton myasthenic syndrome IgG depletes presynaptic membrane active zone particles by antigenic modulationQ41338464
Cross-linking of presynaptic calcium channels: a mechanism of action for Lambert-Eaton myasthenic syndrome antibodies at the mouse neuromuscular junctionQ41559275
Association between Campylobacter infection and Guillain-Barré syndromeQ41660351
Anti‐GM1 IgG antibodies and campylobacter bacteria in Guillain‐Barré syndrome: Evidence of molecular mimicryQ42277583
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Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviorsQ42628411
Anti-N-methyl-D-aspartate receptor encephalitis during pregnancy.Q42972398
Anti-N-methyl-D-aspartate receptor antibodies: a potentially treatable cause of encephalitis in the intensive care unitQ43218065
Effect of LPS on the permeability of the blood-brain barrier to insulinQ43558962
Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient miceQ43646279
A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosusQ43786936
Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: ultrastructural and light microscopic localization and electrophysiologic correlationsQ43866400
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Further postmortem autoradiographic studies of AMPA receptor binding in schizophreniaQ44069097
Spatial memory dissociations in mice lacking GluR1.Q44114033
Corticotropin-releasing hormone and brain mast cells regulate blood-brain-barrier permeability induced by acute stressQ44220866
Altered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of SchizophreniaQ37306496
Autoimmune myasthenia gravis: emerging clinical and biological heterogeneityQ37315963
Association of arthrogryposis multiplex congenita with maternal antibodies inhibiting fetal acetylcholine receptor functionQ37361552
Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss.Q37387340
Autoimmune disorders of the neuromuscular junctionQ37475932
A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroliginQ37535578
Developmental and regional expression in the rat brain and functional properties of four NMDA receptorsQ28570615
Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptorQ28588523
Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunitQ28592875
The cell biology of synaptic plasticity: AMPA receptor traffickingQ29615771
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responsesQ29618915
Anti-NMDA receptor encephalitis in Japan: long-term outcome without tumor removal.Q30484724
Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupusQ30485404
Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndromeQ30827235
Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibodyQ30920813
Limbic encephalitis and variants: classification, diagnosis and treatment.Q31127230
Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression.Q31940595
Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob diseaseQ33375581
Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypesQ33556077
Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen.Q33666104
A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis opticaQ33727402
Developmental seizure susceptibility of kv1.1 potassium channel knockout miceQ33781005
NMDA receptor hypofunction model of schizophreniaQ33813143
Lambert-Eaton myasthenic syndrome as an autoimmune calcium-channelopathyQ33843210
Peripheral injections of Freund's adjuvant in mice provoke leakage of serum proteins through the blood-brain barrier without inducing reactive gliosisQ33865528
Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patientsQ33907001
Apheresis treatment in Lambert-Eaton myasthenic syndromeQ33916821
Paraneoplastic syndromes of the nervous systemQ33931301
Passive transfer of autoimmune autonomic neuropathy to miceQ33938477
Incidence of Guillain-Barré syndrome following infection with Campylobacter jejuniQ33938778
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasoundQ33992793
Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1).Q33997506
Teratogen update: maternal myasthenia gravis as a cause of congenital arthrogryposisQ34058599
Effects of ketamine in normal and schizophrenic volunteersQ34091266
Paraneoplastic syndromes of the spinal cord, nerve, and muscleQ34096509
NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophreniaQ34149624
Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea.Q34207767
Regulation of acetylcholine receptor alpha subunit variants in human myasthenia gravis. Quantification of steady-state levels of messenger RNA in muscle biopsy using the polymerase chain reaction.Q34233629
Immunity and behavior: antibodies alter emotionQ34270963
Acquired neuromyotonia: evidence for autoantibodies directed against K+ channels of peripheral nervesQ34289244
Delivery of melanoma-associated immunoglobulin monoclonal antibody and Fab fragments to normal brain utilizing osmotic blood-brain barrier disruptionQ44991153
Beyond the dopamine hypothesis to the NMDA glutamate receptor hypofunction hypothesis of schizophrenia.Q45935762
Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsyQ46052051
Reduced N-acetylaspartate in the basal ganglia of a patient with anti-NMDA receptor encephalitisQ46122239
The genetics of schizophrenia converge upon the NMDA glutamate receptor.Q46149556
Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis.Q46267461
Development of human visual cortex: a balance between excitatory and inhibitory plasticity mechanismsQ46385324
Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophreniaQ46473954
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophreniaQ46505377
Paraneoplastic encephalitis associated with ovarian teratoma and N-methyl-D-aspartate receptor antibodiesQ46879776
Glutamate AMPA receptor subunit 1 gene (GRIA1) and DSM-IV-TR schizophrenia: a pilot case-control association study in an Italian sampleQ46982053
Neuronal nicotinic ACh receptor antibody in subacute autonomic neuropathy and cancer-related syndromesQ47951852
Effects of Mothers' Autoimmune Disease During Pregnancy on Learning Disabilities and Hand Preference in Their ChildrenQ47974068
Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitisQ48111449
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learningQ48189640
Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B.Q48242571
Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP.Q48385892
Altered NMDA receptor expression and behavior following postnatal hypoxia: potential relevance to schizophrenia.Q48391660
Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memoryQ48395493
Ongoing epileptiform activity in the post-ischemic hippocampus is associated with a permanent shift of the excitatory-inhibitory synaptic balance in CA3 pyramidal neurons.Q48484041
The influence of systemic lupus erythematosus on fetal development: cognitive, behavioral, and health trends.Q48665652
Enhanced LTP in mice deficient in the AMPA receptor GluR2.Q48875091
Zinc has opposite effects on NMDA and non-NMDA receptors expressed in Xenopus oocytesQ48987834
Paraneoplastic limbic encephalitis in a teenage girl with an immature ovarian teratomaQ49029091
Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors.Q51421065
Neuropsychiatric syndromes in lupus: prevalence using standardized definitions.Q51957611
Model psychoses and schizophreniaQ52139726
Campylobacter jejuni infection and Guillain-Barré syndrome.Q55063212
The Epidemiology of Myasthenia GravisQ56883623
Lambert-eaton myasthenic syndromeQ64043897
Myasthenia Gravis: Passive Transfer from Man to MouseQ67318954
Myasthenic Antibodies Cross-Link Acetylcholine Receptors to Accelerate DegradationQ67320379
Plasmapheresis and immunosuppressive drug therapy in myasthenia gravisQ67700665
Calcium channel autoantibodies in Lambert-Eaton myasthenic syndromeQ69375662
Passive transfer of the Lambert-Eaton myasthenic syndrome: neuromuscular transmission in mice injected with plasmaQ70106954
Antibodies to motor nerve terminals: an electrophysiological study of a human myasthenic syndrome transferred to mouseQ71147638
Ultrastructural localization of the terminal and lytic ninth complement component (C9) at the motor end-plate in myasthenia gravisQ71188155
Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigenQ71851780
Acetylcholine release in myasthenia gravis: regulation at single end-plate levelQ72249450
Knockdown of AMPA receptor GluR2 expression causes delayed neurodegeneration and increases damage by sublethal ischemia in hippocampal CA1 and CA3 neuronsQ73107263
Mechanism of block of nicotinic acetylcholine receptor channels by purified IgG from seropositive patients with myasthenia gravisQ73433373
Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an 'adult' acetylcholine receptor subunitQ73857348
Sydenham's choreaQ74093237
Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathiesQ74339283
Guillain-Barré syndromeQ77326744
[Three patients with a paraneoplastic neurological syndrome: the significance of paraneoplastic antibodies]Q80245793
A relative weak leg muscle in the rolling Nagoya mouse as a model for Lambert-Eaton myasthenic syndromeQ81695894
Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brainQ34306593
NMDA receptors, place cells and hippocampal spatial memoryQ34315328
Streptococcal mimicry and antibody-mediated cell signaling in the pathogenesis of Sydenham's choreaQ34491027
Neuromyotonia and limbic encephalitis sera target mature Shaker-type K+ channels: subunit specificity correlates with clinical manifestationsQ34513708
Progress towards validating the NMDA receptor hypofunction hypothesis of schizophreniaQ34529602
Maternal neuronal antibodies associated with autism and a language disorderQ34532394
Antibody-mediated neuronal cell signaling in behavior and movement disordersQ34552211
NMDA receptor subunits: function and pharmacology.Q34579640
Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autismQ34588189
Progressive encephalomyelitis, rigidity, and myoclonus: a novel glycine receptor antibodyQ34598388
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location.Q34972785
Expanding spectrum of encephalitis with NMDA receptor antibodies in young childrenQ35008179
Human lupus autoantibodies against NMDA receptors mediate cognitive impairment.Q35225108
NMDA receptor function, neuroplasticity, and the pathophysiology of schizophreniaQ35684752
The Guillain-Barré syndrome: a true case of molecular mimicryQ35753097
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptorsQ35858251
Amino terminal domain regulation of NMDA receptor functionQ35908506
Excitatory-inhibitory balance and critical period plasticity in developing visual cortexQ35974463
N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological diseaseQ35999737
Paraneoplastic disorders of the central nervous system: update on diagnostic criteria and treatment.Q36002319
Autoimmune limbic encephalitis in 39 patients: immunophenotypes and outcomes.Q36143265
Human autoantibodies specific for the alpha1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons.Q36174877
Role of AMPA receptors in synaptic plasticityQ36560422
Paraneoplastic syndromes of the CNS.Q36631871
Animal model of schizophrenia: dysfunction of NMDA receptor-signaling in mice following withdrawal from repeated administration of phencyclidineQ36690878
Epilepsy, E/I Balance and GABA(A) Receptor Plasticity.Q36852883
Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?Q36860053
Detection of Pneumocystis carinii with DNA-binding bisBenzimide 33258 HoechstQ36895810
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine siteQ36954416
Neuronal surface antigen antibodies in limbic encephalitis: clinical-immunologic associations.Q36982702
Paraneoplastic neurological syndromes: diagnosis and treatmentQ36997070
Autoimmune autonomic ganglionopathy: IgG effects on ganglionic acetylcholine receptor currentQ37041978
Phencyclidine, NMDA receptor and schizophreniaQ37102007
Thymoma, myasthenia gravis, and other paraneoplastic syndromesQ37177981
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectencephalitisQ199615
P304page(s)298-309
P577publication date2010-07-14
P1433published inEuropean Journal of NeuroscienceQ5412733
P1476titleMechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies
P478volume32

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