The projection domain of MAP4 suppresses the microtubule-bundling activity of the microtubule-binding domain

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The projection domain of MAP4 suppresses the microtubule-bundling activity of the microtubule-binding domain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0022-2836(02)00402-3
P698PubMed publication ID12079337

P2093author name stringShin-ichi Hisanaga
Hiromu Murofushi
Hirokazu Hotani
Tomohiko J Itoh
Junko Iida
Jeannette C Bulinski
Ken-ichiro Nishiyama
P2860cites workA protein factor essential for microtubule assemblyQ22010837
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tauQ24648590
Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamicsQ24672791
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerizationQ33900263
Microtubules and microtubule-associated proteinsQ34311088
MAP4 is the in vivo substrate for CDC2 kinase in HeLa cells: identification of an M-phase specific and a cell cycle-independent phosphorylation site in MAP4.Q34449209
Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitroQ35084038
Microtubule Assembly in the Absence of Added NucleotidesQ35098486
The periodic association of MAP2 with brain microtubules in vitroQ36200431
Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivoQ36202089
Purification and characterization of a 190-kD microtubule-associated protein from bovine adrenal cortexQ36215824
Stable expression of heterologous microtubule-associated proteins (MAPs) in Chinese hamster ovary cells: evidence for differing roles of MAPs in microtubule organizationQ36234464
Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimerasQ36235827
Microtubule-stabilizing activity of microtubule-associated proteins (MAPs) is due to increase in frequency of rescue in dynamic instability: shortening length decreases with binding of MAPs onto microtubulesQ36715361
Bundling of microtubules in transfected cells does not involve an autonomous dimerization site on the MAP2 moleculeQ40366060
Microtubule organization and dynamics dependent on microtubule-associated proteinsQ40744920
Microinjection of intact MAP-4 and fragments induces changes of the cytoskeleton in PtK2 cellsQ41249254
Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.Q41585811
Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axonsQ41589236
The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptideQ41591267
Domain structure and antiparallel dimers of microtubule-associated protein 2 (MAP2)Q43750533
The primary structure and heterogeneity of tau protein from mouse brainQ48122949
Microtubule-associated protein MAP2 shares a microtubule binding motif with tau proteinQ48311549
Phosphorylation states of microtubule-associated protein 2 (MAP2) determine the regulatory role of MAP2 in microtubule dynamicsQ48605036
Effect of microtubule-associated proteins on the protofilament number of microtubules assembled in vitro.Q48642573
Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tauQ59067304
Domains of tau protein and interactions with microtubulesQ72146653
A new model for microtubule-associated protein (MAP)-induced microtubule assembly. The Pro-rich region of MAP4 promotes nucleation of microtubule assembly in vitroQ77892780
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)97-106
P577publication date2002-06-01
P1433published inJournal of Molecular BiologyQ925779
P1476titleThe projection domain of MAP4 suppresses the microtubule-bundling activity of the microtubule-binding domain
P478volume320

Reverse relations

cites work (P2860)
Q40277408Differences in the regulation of microtubule stability by the pro-rich region variants of microtubule-associated protein 4.
Q44430566Different protofilament-dependence of the microtubule binding between MAP2 and MAP4
Q37621709Higher-order assembly of microtubules by counterions: from hexagonal bundles to living necklaces.
Q41986825MAP2-mediated in vitro interactions of brain microtubules and their modulation by cAMP.
Q41929231MAP4-dependent regulation of microtubule formation affects centrosome, cilia, and Golgi architecture as a central mechanism in growth regulation.
Q24299072MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes
Q30437741Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.
Q42067060Microtubule teardrop patterns
Q40638420Microtubules are critical for radial glial morphology: possible regulation by MAPs and MARKs.
Q30476790Radial compression of microtubules and the mechanism of action of taxol and associated proteins.
Q33967417Site-specific microtubule-associated protein 4 dephosphorylation causes microtubule network densification in pressure overload cardiac hypertrophy
Q24529075The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules
Q34201054The number of repeat sequences in microtubule-associated protein 4 affects the microtubule surface properties

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