Attenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities

scientific article

Attenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/0471142956.CY0947S69
P932PMC publication ID4156839
P698PubMed publication ID24984966
P5875ResearchGate publication ID264633744

P50authorZbyszek DarzynkiewiczQ33103772
Hong ZhaoQ77639007
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A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
mTOR: from growth signal integration to cancer, diabetes and ageingQ24633662
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesisQ24681977
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Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksQ28255399
DNA topoisomerases and their poisoning by anticancer and antibacterial drugsQ28284744
Telomeres shorten during ageing of human fibroblastsQ29547357
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblastsQ29618748
Laser-scanning cytometry: A new instrumentation with many applicationsQ30699994
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In search of antiaging modalities: evaluation of mTOR- and ROS/DNA damage-signaling by cytometryQ33841800
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Cellular senescence: mitotic clock or culture shock?Q34019131
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Berberine suppresses gero-conversion from cell cycle arrest to senescenceQ34366519
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Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidantsQ34561662
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signalingQ34567724
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Cellular senescence and chromatin structureQ36853695
Aging: ROS or TOR.Q37312907
Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acidsQ37396644
GammaH2AX as a molecular marker of aging and disease.Q37691177
Fluorescence-based detection and quantification of features of cellular senescence.Q37896791
Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescenceQ39300990
Persistent p21 expression after Nutlin-3a removal is associated with senescence-like arrest in 4N cellsQ39701774
Features of senescence and cell death induced by doxorubicin in A549 cells: organization and level of selected cytoskeletal proteins.Q39777394
Cellular quiescence caused by the Mdm2 inhibitor nutlin-3A.Q39783675
Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiationQ39957013
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processesQ40078756
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant statesQ40250572
Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species.Q40259009
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Replicative senescence of human fibroblast-like cells in cultureQ40825818
Analysis of spatial correlations between patterns of DNA damage response and DNA replication in nuclei of cells subjected to replication stress or oxidative damageQ41901308
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytesQ42806461
Executing Cell SenescenceQ57580197
Executing cell senescenceQ57580253
Interactions of antitumor agents ametantrone∗∗Trade name for the salt of 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione (Fig. 1, I). Abbreviations: HAQ, ANT; NSC-287513. and mitoxantrone (novatrone)††Trade name for the saQ62590633
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisonsQ67671954
P921main subjectcellular senescenceQ9075999
P304page(s)9.47.1-9.47.10
P577publication date2014-07-01
P1433published inCurrent protocols in cytometryQ27721911
P1476titleAttenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities
P478volume69

Reverse relations

cites work (P2860)
Q37644791Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells
Q48178279Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
Q49773776Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-Related Diseases via Anti-Oxidation and AMPK Activation

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