NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration.

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NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2010.09.009
P932PMC publication ID2989827
P698PubMed publication ID21092857
P5875ResearchGate publication ID49624096

P50authorDwight E. BerglesQ48403757
P2093author name stringJeffrey D Rothstein
Masahiro Fukaya
Shin H Kang
Jason K Yang
P2860cites workDevelopment of NG2 neural progenitor cells requires Olig gene functionQ24546061
Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brainQ28565002
Mechanisms and functional implications of adult neurogenesisQ29547295
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutationQ29547561
A global double-fluorescent Cre reporter mouseQ29616157
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.Q30559101
The oligodendrocyte precursor cell in health and diseaseQ31865249
Focal degeneration of astrocytes in amyotrophic lateral sclerosis.Q33350786
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic strokeQ33610598
Inflammation in ALS and SMA: sorting out the good from the evilQ33664711
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord.Q33892412
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degenerationQ33954016
PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage.Q33971870
NG2 cells generate both oligodendrocytes and gray matter astrocytes.Q34719495
Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter.Q34756911
Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex.Q34848711
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice.Q34851255
Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticityQ34908170
Regulation of oligodendrocyte development in the vertebrate CNS.Q34973857
The NG2 proteoglycan: past insights and future prospectsQ35539062
Vesicular release of glutamate from unmyelinated axons in white matterQ36275086
NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus.Q36322398
Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neuronsQ36323410
How widespread is adult neurogenesis in mammals?Q36827189
Reduced EGFR signaling in progenitor cells of the adult subventricular zone attenuates oligodendrogenesis after demyelinationQ37227164
Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injuryQ37251418
Early postnatal proteolipid promoter-expressing progenitors produce multilineage cells in vivoQ37280371
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyondQ37642283
Postnatal neurogenesis and gliogenesis in the olfactory bulb from NG2-expressing progenitors of the subventricular zone.Q38334176
The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brainQ40489230
Cell cycle dynamics of NG2 cells in the postnatal and ageing brainQ43117221
Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesionQ43613142
Inducible site-specific recombination in myelinating cellsQ44248492
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.Q44376589
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.Q46021705
Adult glial precursor proliferation in mutant SOD1G93A miceQ46893498
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.Q47951637
Oligodendrocyte population dynamics and the role of PDGF in vivo.Q47992103
Development and differentiation of glial precursor cells in the rat cerebellumQ48315261
Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord.Q48490617
The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.Q48546876
Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.Q48611307
NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord.Q48829039
Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells.Q52165452
Heterogeneity of NG2-expressing cells in the newborn mouse cerebellum.Q53848455
The oligodendrocyte-type-2 astrocyte cell lineage is specialized for myelinationQ59077905
Increased stem cell proliferation in the spinal cord of adult amyotrophic lateral sclerosis transgenic miceQ80247749
Myelination and the trophic support of long axonsQ83162670
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectoligodendrocyteQ916698
neurodegenerationQ1755122
P304page(s)668-681
P577publication date2010-11-01
P1433published inNeuronQ3338676
P1476titleNG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration
P478volume68

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Q50115751Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.
Q37677116Spatial organization of NG2 glial cells and astrocytes in rat hippocampal CA1 region
Q90021339Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis
Q89979809Spatiotemporal Profile and Morphological Changes of NG2 Glia in the CA1 Region of the Rat Hippocampus after Transient Forebrain Ischemia
Q35748916Spinal Glia Division Contributes to Conditioning Lesion-Induced Axon Regeneration Into the Injured Spinal Cord: Potential Role of Cyclic AMP-Induced Tissue Inhibitor of Metalloproteinase-1
Q44494607Stab wound injury of the zebrafish telencephalon: a model for comparative analysis of reactive gliosis
Q41808119Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development.
Q53065845Stage-specific requirement for cyclin D1 in glial progenitor cells of the cerebral cortex.
Q90845295Stem cell derived oligodendrocytes to study myelin diseases
Q34253152Structural reorganization of pyramidal neurons in the medial prefrontal cortex of alcohol dependent rats is associated with altered glial plasticity
Q37852077Synapses between NG2 glia and neurons
Q38175968Synaptic integration by NG2 cells
Q37351902Tamoxifen in the Mouse Brain: Implications for Fate-Mapping Studies Using the Tamoxifen-Inducible Cre-loxP System
Q38784277Targeting human oligodendrocyte progenitors for myelin repair
Q29346954Targeting of vasoactive intestinal peptide receptor 2, VPAC2, a secretin family G-protein coupled receptor, to primary cilia
Q38223428The (real) neurogenic/gliogenic potential of the postnatal and adult brain parenchyma
Q92799343The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming
Q51043397The ESCRT-deubiquitinating enzyme USP8 in the cervical spinal cord of wild-type and Vps54-recessive (wobbler) mutant mice.
Q48873464The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage.
Q38658419The Role of the Oligodendrocyte Lineage in Acute Brain Trauma.
Q58745277The Significance of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Human Gliomas
Q27342581The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination
Q34458989The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.
Q82565310The astrocytic lineage marker calmodulin-regulated spectrin-associated protein 1 (Camsap1): phenotypic heterogeneity of newly born Camsap1-expressing cells in injured mouse brain
Q34643485The curious case of NG2 cells: transient trend or game changer?
Q38264398The emerging functions of oligodendrocytes in regulating neuronal network behaviour
Q92745530The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury
Q99593502The integrated UPR and ERAD in oligodendrocytes maintains myelin thickness in adults by regulating myelin protein translation
Q38126396The multifaceted role of glial cells in amyotrophic lateral sclerosis
Q64111109The platelet-derived growth factor receptor alpha promoter-directed expression of cre recombinase in mouse placenta
Q33900243The proteolipid protein promoter drives expression outside of the oligodendrocyte lineage during embryonic and early postnatal development
Q36520580The reactions and role of NG2 glia in spinal cord injury
Q58563377The regulation of the homeostasis and regeneration of peripheral nerve is distinct from the CNS and independent of a stem cell population
Q38237223The role of oligodendroglial dysfunction in amyotrophic lateral sclerosis
Q37830315The stem cell potential of glia: lessons from reactive gliosis
Q38180416The translational biology of remyelination: past, present, and future
Q90666605The voltage-gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex
Q34262386Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse
Q39433671Tracking Adventitial Fibroblast Contribution to Disease: A Review of Current Methods to Identify Resident Fibroblasts
Q38698838Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus.
Q58736166Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development
Q47184242Transient Cnp expression by early progenitors causes Cre-Lox-based reporter lines to map profoundly different fates.
Q36394283Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.
Q45931166Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain.
Q91592654Uncovering the biology of myelin with optical imaging of the live brain
Q28078778Understanding the NG2 Glial Scar after Spinal Cord Injury
Q101226560Unraveling the adult cell progeny of early postnatal progenitor cells
Q51058077VEGF treatment during status epilepticus attenuates long-term seizure-associated alterations in astrocyte morphology.
Q34037564VGluT1+ neuronal glutamatergic signaling regulates postnatal developmental maturation of cortical protoplasmic astroglia
Q48434758WITHDRAWN: Functional implications of hypothalamic neurogenesis in the adult mammalian brain.
Q38368748Wrapped to Adapt: Experience-Dependent Myelination
Q33894302Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination.
Q38255026Zebrafish as a model to investigate CNS myelination

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