In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents

scientific article

In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI117256
P932PMC publication ID294458
P698PubMed publication ID8200983

P50authorShimon EfratQ42347994
P2093author name stringY Liang
S Bonner-Weir
Y J Wu
F M Matschinsky
D K Berner
C D Berdanier
P2860cites workGlucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationshipsQ24322186
The Zucker fatty rat as a genetic model of obesity and hypertensionQ28279616
[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasisQ33610697
The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequenceQ33985925
Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitusQ34061740
Autoantibodies to the GLUT-2 glucose transporter of beta cells in insulin-dependent diabetes mellitus of recent onsetQ36098927
Tissue-specific regulation of glucokinase gene expressionQ36270290
Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cellsQ36427862
Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cellsQ36756348
Heterogeneous expression of glucokinase among pancreatic beta cellsQ36912605
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin releaseQ36989349
G proteins and modulation of insulin secretionQ37328957
Chromatographic resolution and kinetic characterization of glucokinase from islets of LangerhansQ37600299
Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cellsQ37671830
The BHE rat: an animal model for the study of non-insulin-dependent diabetes mellitusQ37707507
Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytesQ37928457
Pancreatic islet glucose metabolism and regulation of insulin secretionQ39479486
Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ CultureQ41125056
G-proteins and hormonal inhibition of insulin secretion from HIT-T15 cells and isolated rat isletsQ41596271
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Radiometric oil well assay for glucokinase in microscopic structures.Q53851272
Metabolic Adaption of Pancreatic Islet Tissue in Aging RatsQ54485216
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Inhibition of glucose transport into rat islet cells by immunoglobulins from patients with new-onset insulin-dependent diabetes mellitusQ68930016
Gestational diabetes in the BHE rat: influence of dietary fatQ69661878
Metabolism of glucose in the islets of LangerhansQ69840926
Studies with the mutation, diabetes, in the mouseQ69900725
Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic isletsQ69912125
Differential regulation of glucokinase activity in pancreatic islets and liver of the ratQ70144330
Coated Charcoal Immunoassay of InsulinQ71162157
Regulation of Glucose Metabolism in Pancreatic IsletsQ72912008
GLUCOKINASE OF RABBIT LIVERQ78328158
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
P304page(s)2473-2481
P577publication date1994-06-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleIn situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents
P478volume93