The micronutrient indole-3-carbinol: implications for disease and chemoprevention

scientific article

The micronutrient indole-3-carbinol: implications for disease and chemoprevention is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1515/DMDI.2000.17.1-4.159
P698PubMed publication ID11201294

P2093author name stringShertzer HG
Senft AP
P2860cites workSuppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexesQ22254383
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosisQ28140867
Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosisQ28273735
A review of mechanisms underlying anticarcinogenicity by brassica vegetablesQ28305035
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxinQ28321853
Induction of estradiol metabolism by dietary indole-3-carbinol in humansQ28335039
The aryl hydrocarbon receptor complexQ29618805
Multifunctional aspects of the action of indole-3-carbinol as an antitumor agentQ33834356
In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indolesQ33875990
Functional role of estrogen metabolism in target cells: review and perspectivesQ34457135
Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compoundsQ39251167
Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agentsQ40667195
The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathwayQ40903006
Mechanisms of chemical mediated cytotoxicity and chemoprotection in isolated rat hepatocytesQ41165143
Mechanisms of anti-carcinogenesis by indole-3-carbinol. Studies of enzyme induction, electrophile-scavenging, and inhibition of aflatoxin B1 activationQ41177694
Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cellsQ41204412
Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolismQ41447733
Protection against carbon tetrachloride hepatotoxicity by pretreatment with indole-3-carbinolQ41454163
Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent.Q41493982
Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, a major in vivo product of dietary indole-3-carbinolQ41685521
Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis modelQ42435384
Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the ratQ42454451
Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley ratsQ42496615
Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkersQ42538476
Mechanisms of action of indole-3-carbinol as a chemopreventive agentQ42818991
The anti-carcinogenic plant compound indole-3-carbinol differentially modulates P450-mediated steroid hydroxylase activities in miceQ43497831
Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesisQ44103502
Oligomerization of indole-3-carbinol in aqueous acidQ44439558
Effect of the plant compound indole-3-carbinol on hepatic cholesterol homoeostasisQ44864222
Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.Q46728776
Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adducts by indole-3-carbinol: dose-response studies in the rat colonQ50132743
Genotoxicities of nitropyrenes and their modulation by apigenin, tannic acid, ellagic acid and indole-3-carbinol in the Salmonella and CHO systems.Q50170664
Mutagen formation on nitrite treatment of indole compounds derived from indole-glucosinolateQ50184884
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.Q53407200
Inhibition of cigarette smoke-related DNA adducts in rat tissues by indole-3-carbinol.Q53407933
Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3-methylimidazo[4,5-f]quinoline by dietary indole-3-carbinol in female rats.Q53421536
Prevention of cyclophosphamide-induced micronucleus formation in mouse bone marrow by indole-3-carbinol.Q53430280
Inhibition of proliferation and modulation of estradiol metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.Q53437589
Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice.Q53496585
Treatment of recurrent respiratory papillomatosis with indole-3-carbinolQ57665731
Alterations in estradiol metabolism in MCF-7 cells induced by treatment with indole-3-carbinol and related compoundsQ57665748
Altered estrogen metabolism and excretion in humans following consumption of indole‐3‐carbinolQ57665784
Influence of indole-3-carbinol on the hepatic microsomal formation of catechol estrogensQ57665789
P433issue1-4
P921main subjectindole-3-carbinolQ1770257
P304page(s)159-188
P577publication date2000-01-01
P1433published inDrug Metabolism and Drug InteractionsQ23933852
P1476titleThe micronutrient indole-3-carbinol: implications for disease and chemoprevention
P478volume17

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cites work (P2860)
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Q35846299Vegetable and fruit intake after diagnosis and risk of prostate cancer progression
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Q48573274WITHDRAWN: The anti-cancer properties in parallel with toxic effects of indole-3-carbinol derivatives
Q33856030What should we tell prostate cancer patients about (secondary) prevention?

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