Interleukins in chronic liver disease: lessons learned from experimental mouse models

scientific article

Interleukins in chronic liver disease: lessons learned from experimental mouse models is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.2147/CEG.S43737
P932PMC publication ID4158890
P698PubMed publication ID25214799
P5875ResearchGate publication ID265606880

P50authorFrank TackeQ62748536
Linda HammerichQ82224121
P2860cites workEvolutionary divergence and functions of the human interleukin (IL) gene familyQ21245454
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokinesQ24294720
Therapeutic strategies for the clinical blockade of IL-6/gp130 signalingQ27002391
Gp130 and the interleukin-6 family of cytokinesQ28237653
IL-22 increases the innate immunity of tissuesQ28276850
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling systemQ28585033
IL-33 reduces the development of atherosclerosisQ28594104
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 productionQ29614596
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generationQ29614840
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expressionQ29615766
Immunologic messenger molecules: cytokines, interferons, and chemokinesQ30449522
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory responseQ33853821
Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondiiQ34006279
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.Q34070116
The molecular basis of T helper 1 and T helper 2 cell differentiationQ34106569
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3Q34163926
Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity.Q34491845
Hepatic IL-17 responses in human and murine primary biliary cirrhosisQ35575733
Interleukin-10 modulates type I collagen and matrix metalloprotease gene expression in cultured human skin fibroblastsQ35824711
Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infectionQ36062404
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in miceQ36089631
Innate immunity gone awry: linking microbial infections to chronic inflammation and cancerQ36404654
Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in miceQ36794471
Inflammatory pathways in liver homeostasis and liver injuryQ37207091
Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.Q37311036
Role of IL-17 and Th17 cells in liver diseasesQ37825436
Deciphering and reversing tumor immune suppression.Q38124437
Role of gamma-delta T cells in liver inflammation and fibrosis.Q38217236
Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22.Q38344139
STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.Q38358871
IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma.Q39024081
Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in miceQ39333394
Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat modelQ39938317
Interleukin-10 gene therapy reverses thioacetamide-induced liver fibrosis in miceQ40393876
Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cellsQ40444779
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activationQ40560155
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.Q40910796
Bone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17.Q41853274
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosisQ41945735
Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cellsQ42448855
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injuryQ42541847
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseasesQ44493772
IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells.Q44713685
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agentQ44826352
The regenerative activity of interleukin-6.Q45885453
Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanismQ47894338
Gender disparity of hepatocellular carcinoma: the roles of sex hormones.Q51552877
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis.Q52543547
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis.Q53344106
Procalcitonin as a diagnostic marker and IL-6 as a prognostic marker for sepsis.Q54317622
Lack of gp130 expression in hepatocytes promotes liver injury1 1K.L.S. and T.W. contributed equally to this workQ57339931
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient miceQ58535662
Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in miceQ58619570
The biology of interleukin-6 in the 21st centuryQ62658815
Hepatic release of interleukin-10 during cardiopulmonary bypass in steroid-pretreated patientsQ64127379
Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine productionQ70527759
Interleukin-10 regulation in normal subjects and patients with asthmaQ71120290
IL-10 prevents liver necrosis during murine infection with Trichinella spiralisQ73910734
IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12Q77436972
Interleukin-10 expression and function in experimental murine liver inflammation and fibrosisQ77598613
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in miceQ77598616
Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3Q84365414
Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver diseaseQ85068847
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectliver diseaseQ929737
lessons learnedQ1673259
chronic liver diseaseQ5113984
P304page(s)297-306
P577publication date2014-09-01
P1433published inClinical and Experimental GastroenterologyQ5133804
P1476titleInterleukins in chronic liver disease: lessons learned from experimental mouse models
P478volume7

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