| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1002711479 |
| P356 | DOI | 10.1038/NATURE01108 |
| P698 | PubMed publication ID | 12410314 |
| P5875 | ResearchGate publication ID | 11055106 |
| P50 | author | Nektarios Tavernarakis | Q20986533 |
| Popi Syntichaki | Q21264530 | ||
| Monica Driscoll | Q78823057 | ||
| P2093 | author name string | Keli Xu | |
| P2860 | cites work | The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development | Q24318966 |
| Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans | Q27860867 | ||
| Molecular mechanisms of calcium-dependent excitotoxicity | Q28141475 | ||
| The calpain family and human disease | Q28214119 | ||
| Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3 | Q28645710 | ||
| The structure of calpain. | Q30666576 | ||
| The changing landscape of ischaemic brain injury mechanisms. | Q33678157 | ||
| Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes | Q33888450 | ||
| A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans | Q33930492 | ||
| Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates | Q33935231 | ||
| Calpain inhibitors as therapeutic agents in nerve and muscle degeneration | Q33936871 | ||
| Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum | Q34093243 | ||
| Death by necrosis. Uncontrollable catastrophe, or is there order behind the chaos? | Q34137277 | ||
| unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion | Q34414566 | ||
| Organelle-specific initiation of cell death pathways | Q34443559 | ||
| The tra-3 sex determination gene of Caenorhabditis elegans encodes a member of the calpain regulatory protease family. | Q35907418 | ||
| An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration | Q38344950 | ||
| Regulation of proteinase levels in the nematode Caenorhabditis elegans. Preferential depression by acute or chronic starvation | Q41849547 | ||
| Aspartic proteases from the nematode Caenorhabditis elegans. Structural organization and developmental and cell-specific expression of asp-1. | Q47069259 | ||
| G alphas-induced neurodegeneration in Caenorhabditis elegans. | Q47069506 | ||
| A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans | Q48074917 | ||
| The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration | Q48235681 | ||
| Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease. | Q53343959 | ||
| The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans | Q59088240 | ||
| Neuropathology of degenerative cell death in Caenorhabditis elegans | Q71971010 | ||
| P433 | issue | 6910 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Caenorhabditis elegans | Q91703 |
| neurodegeneration | Q1755122 | ||
| thapsigargin | Q3981006 | ||
| CaLPain family CELE_Y47H10A.1 | Q29793757 | ||
| ASpartyl Protease CELE_R12H7.2 | Q29795214 | ||
| Aspartic protease 3 CELE_H22K11.1 | Q29798679 | ||
| P304 | page(s) | 939-944 | |
| P577 | publication date | 2002-10-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans | |
| P478 | volume | 419 |
| Q30833652 | A Disease Model of Muscle Necrosis Caused by Aeromonas dhakensis Infection in Caenorhabditis elegans |
| Q50194234 | A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively. |
| Q36368863 | A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress |
| Q34245698 | A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans |
| Q46874526 | A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells |
| Q43284474 | Alteration of the nuclear pore complex in Ca(2+)-mediated cell death. |
| Q34362382 | Alternative cell death mechanisms in development and beyond |
| Q47136494 | An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration |
| Q24294713 | An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury |
| Q21092703 | Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans |
| Q41575658 | Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function. |
| Q37661301 | Antioxidant response is a protective mechanism against nutrient deprivation in C. elegans |
| Q36409990 | Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities |
| Q34694960 | Autophagy is required for necrotic cell death in Caenorhabditis elegans. |
| Q34119935 | Autophagy protects C. elegans against necrosis during Pseudomonas aeruginosa infection |
| Q36897647 | Autophagy protects against hypoxic injury in C. elegans |
| Q35900236 | Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1). |
| Q90623130 | Bacterially produced metabolites protect C. elegans neurons from degeneration |
| Q34066765 | Beta-secretase: structure, function, and evolution |
| Q98288800 | Beyond Host Defense: Deregulation of Drosophila Immunity and Age-Dependent Neurodegeneration |
| Q35250638 | CAPN5 gene silencing by short hairpin RNA interference. |
| Q92558825 | CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials |
| Q35882582 | CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model |
| Q37041556 | CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans |
| Q39269905 | Ca2+ permeability and Na+ conductance in cellular toxicity caused by hyperactive DEG/ENaC channels |
| Q38567060 | Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33 |
| Q35548623 | Calcium-dependent and aspartyl proteases in neurodegeneration and ageing in C. elegans |
| Q28584194 | Calpain 1 and Calpastatin expression is developmentally regulated in rat brain |
| Q33888505 | Calpain 5 is highly expressed in the central nervous system (CNS), carries dual nuclear localization signals, and is associated with nuclear promyelocytic leukemia protein bodies |
| Q33649868 | Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense |
| Q35157505 | Calpain chronicle--an enzyme family under multidisciplinary characterization |
| Q37324405 | Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells |
| Q27335029 | Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans |
| Q35999742 | Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury |
| Q30499344 | Caspase-independent pathways of hair cell death induced by kanamycin in vivo |
| Q64008486 | Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study |
| Q28269343 | Cell death in the nervous system |
| Q35564610 | Cell-death alternative model organisms: why and which? |
| Q27355204 | Cell-specific monitoring of protein synthesis in vivo |
| Q34298023 | Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94. |
| Q42590164 | Constitutive activation of the pH-responsive Rim101 pathway in yeast mutants defective in late steps of the MVB/ESCRT pathway |
| Q36893318 | Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle |
| Q37631165 | Delayed innocent bystander cell death following hypoxia in Caenorhabditis elegans |
| Q48138457 | Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity. |
| Q34539839 | Diapause formation and downregulation of insulin-like signaling via DAF-16/FOXO delays axonal degeneration and neuronal loss |
| Q61818318 | Diapause induces functional axonal regeneration after necrotic insult in C. elegans |
| Q24675682 | Dictyostelium cell death: early emergence and demise of highly polarized paddle cells |
| Q45256092 | Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. |
| Q33436423 | Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans |
| Q35558449 | Diversity in the mechanisms of neuronal cell death. |
| Q35074847 | Dying for a cause: invertebrate genetics takes on human neurodegeneration |
| Q53589033 | EGF signaling overcomes a uterine cell death associated with temporal mis-coordination of organogenesis within the C. elegans egg-laying apparatus. |
| Q50891679 | Efficient expression and purification of recombinant human μ-calpain using an Escherichia coli expression system. |
| Q34239748 | Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans |
| Q57939265 | Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease |
| Q46147097 | Expression and characterization of aspartic protease gene in eggs and larvae stage of Ancylostoma caninum. |
| Q47068916 | First identification of a phosphorylcholine-substituted protein from Caenorhabditis elegans: isolation and characterization of the aspartyl protease ASP-6. |
| Q37708377 | Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina |
| Q93389616 | Genetic analysis of KillerRed in C. elegans identifies a shared role of calcium genes in ROS-mediated neurodegeneration |
| Q34361274 | Genetic control of necrosis - another type of programmed cell death |
| Q34350636 | Genetic models of mechanotransduction: the nematode Caenorhabditis elegans |
| Q36643300 | Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection |
| Q52339397 | Glial loss of the metallo β-lactamase domain containing protein, SWIP-10, induces age- and glutamate-signaling dependent, dopamine neuron degeneration. |
| Q44700253 | Glutamate activates NF-kappaB through calpain in neurons |
| Q36389497 | Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans |
| Q27012978 | Hsp70.1 and related lysosomal factors for necrotic neuronal death |
| Q36579435 | Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis |
| Q30492757 | Identification of novel aspartic proteases from Strongyloides ratti and characterisation of their evolutionary relationships, stage-specific expression and molecular structure |
| Q37879317 | Impact of genetic insights into calpain biology |
| Q51747909 | Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. |
| Q80538036 | Introduction-cell death in heart failure |
| Q35828412 | Key note lecture: toward a mechanistic taxonomy for cell death programs |
| Q38618355 | Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans. |
| Q34517224 | Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans |
| Q27004531 | Lysosomal storage diseases and the heat shock response: convergences and therapeutic opportunities |
| Q37497722 | Lysosomes as "suicide bags" in cell death: myth or reality? |
| Q36045199 | Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies |
| Q37029897 | Mechanistic role of calpains in postischemic neurodegeneration |
| Q39668869 | Meta-analysis of the association between four CAPN10 gene variants and gestational diabetes mellitus |
| Q28485135 | Metabolic labeling of Caenorhabditis elegans primary embryonic cells with azido-sugars as a tool for glycoprotein discovery |
| Q84561174 | Metacaspases are not caspases--always doubt |
| Q36767908 | Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress |
| Q37293096 | Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans |
| Q35239947 | Modulatory profiling identifies mechanisms of small molecule-induced cell death. |
| Q40037129 | N terminus of calpain 1 is a mitochondrial targeting sequence |
| Q37727615 | NRA-2, a nicalin homolog, regulates neuronal death by controlling surface localization of toxic Caenorhabditis elegans DEG/ENaC channels |
| Q41586826 | Necrosis in C. elegans |
| Q41409358 | Necrotic cell death and neurodegeneration: The involvement of endocytosis and intracellular trafficking |
| Q46296163 | Necrotic cell death: From reversible mitochondrial uncoupling to irreversible lysosomal permeabilization |
| Q48177436 | Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons. |
| Q34281303 | Neuronal necrosis is regulated by a conserved chromatin-modifying cascade |
| Q37055480 | Neurotoxic unc-8 mutants encode constitutively active DEG/ENaC channels that are blocked by divalent cations |
| Q37682750 | Non-apoptotic cell death in Caenorhabditis elegans |
| Q33973337 | Noncanonical cell death in the nematode Caenorhabditis elegans |
| Q37147746 | Noncanonical cell death programs in the nematode Caenorhabditis elegans |
| Q42585387 | Nuclear pore complex during neuronal degeneration: cracking the last barrier! |
| Q92522492 | Olfactory receptor neurons express olfactory marker protein but not calpain 5 from the same genomic locus |
| Q38235868 | Organelle-specific initiation of cell death |
| Q38976875 | Plant life needs cell death, but does plant cell death need Cys proteases? |
| Q37051197 | Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage. |
| Q88723805 | Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond |
| Q36565686 | Promises and challenges in developing RNAi as a research tool and therapy for neurodegenerative diseases |
| Q38663181 | Protease signaling in animal and plant-regulated cell death |
| Q36156010 | Proteolytic mechanisms in necrotic cell death and neurodegeneration |
| Q39474606 | Reactive oxygen species-mediated neurodegeneration is independent of the ryanodine receptor in Caernorhabditis elegans |
| Q34039639 | Regulated necrosis: the expanding network of non-apoptotic cell death pathways. |
| Q35743096 | Regulation of the apoptosis-necrosis switch |
| Q38855737 | Retinal Cell Death Caused by Sodium Iodate Involves Multiple Caspase-Dependent and Caspase-Independent Cell-Death Pathways |
| Q36111729 | Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay. |
| Q34299392 | Small heat-shock proteins protect from heat-stroke-associated neurodegeneration |
| Q52019760 | Staying alive in adversity: transcriptome dynamics in the stress-resistant dauer larva. |
| Q38315864 | Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP. |
| Q92851919 | Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants |
| Q35347586 | Structural modeling of a novel CAPN5 mutation that causes uveitis and neovascular retinal detachment |
| Q28535104 | Substrate-driven mapping of the degradome by comparison of sequence logos |
| Q48144552 | Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates |
| Q34674858 | TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons |
| Q33264001 | The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine |
| Q92702470 | The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans Models |
| Q27334407 | The atypical calpains: evolutionary analyses and roles in Caenorhabditis elegans cellular degeneration |
| Q34219234 | The biochemistry of neuronal necrosis: rogue biology? |
| Q35548609 | The calpains in aging and aging-related diseases |
| Q37196064 | The cell biology of autophagy in metazoans: a developing story |
| Q28744061 | The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight |
| Q36565584 | The long processes of short interfering RNAs--RNA interference and its implications in neuronal cells. |
| Q46229892 | The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation |
| Q40143479 | The plasma membrane Na+/Ca2+ exchanger is cleaved by distinct protease families in neuronal cell death |
| Q28472116 | Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva |
| Q52607336 | Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause. |
| Q33905340 | Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: a scheme for the progression of cardiac dysfunction |
| Q28485411 | Trypanosoma cruzi response to sterol biosynthesis inhibitors: morphophysiological alterations leading to cell death |
| Q37701767 | Tumor necrosis factor-mediated cell death: to break or to burst, that's the question |
| Q46282950 | Two Novel CAPN5 Variants Associated with Mild and Severe Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy Phenotypes. |
| Q36687852 | Using Caenorhabditis elegans models of neurodegenerative disease to identify neuroprotective strategies |
| Q53597656 | VHA-8, the E subunit of V-ATPase, is essential for pH homeostasis and larval development in C. elegans. |
| Q36003655 | Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast |
| Q48826937 | Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia? |
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