| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P356 | DOI | 10.1074/JBC.M206383200 |
| P698 | PubMed publication ID | 12424250 |
| P50 | author | Silvia Bulfone-Paus | Q7516970 |
| Ralf Paus | Q37381598 | ||
| Zane Orinska | Q89001420 | ||
| Elena Bulanova | Q91479005 | ||
| Vadim Budagian | Q117271181 | ||
| Raja Fayad | Q125259726 | ||
| P2093 | author name string | Luba Brovko | |
| P2860 | cites work | The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA | Q24321060 |
| Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells | Q27860599 | ||
| Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners | Q28137807 | ||
| CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes | Q28141639 | ||
| P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse | Q28215178 | ||
| Activation of P2Y2 receptors by UTP and ATP stimulates mitogen-activated kinase activity through a pathway that involves related adhesion focal tyrosine kinase and protein kinase C | Q28260202 | ||
| Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors | Q28344116 | ||
| The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes | Q28379549 | ||
| The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7) | Q28568856 | ||
| The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505 | Q28570842 | ||
| A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP | Q28573068 | ||
| Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor | Q28584997 | ||
| Altered cytokine production in mice lacking P2X(7) receptors | Q28586061 | ||
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo | Q28609356 | ||
| Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines | Q28647261 | ||
| Nucleotide receptors: an emerging family of regulatory molecules in blood cells | Q28678595 | ||
| AP-1 in cell proliferation and survival | Q29615217 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| The regulation of AP-1 activity by mitogen-activated protein kinases | Q29620431 | ||
| The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling | Q30175876 | ||
| The role of cytokine receptor signaling in lymphocyte development | Q33632409 | ||
| Differential requirement for p56lck in HIV-tat versus TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal kinase, and apoptosis | Q33900927 | ||
| Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products | Q33940330 | ||
| Signal transduction by MAP kinases in T lymphocytes | Q33951021 | ||
| Control of the eukaryotic cell cycle by MAP kinase signaling pathways. | Q34071364 | ||
| MAP-kinase signaling pathways in T cells | Q34282347 | ||
| Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons | Q34296118 | ||
| The IKK/NF-kappa B pathway | Q34487840 | ||
| The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role | Q35553460 | ||
| Extracellular ATP as a trigger for apoptosis or programmed cell death | Q36529115 | ||
| Protein kinase C theta cooperates with Vav1 to induce JNK activity in T-cells | Q38302839 | ||
| P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells. | Q38325287 | ||
| The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death | Q40380348 | ||
| Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development. | Q40696081 | ||
| Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase. | Q40829299 | ||
| Activation of c-Jun N-terminal kinase and activator protein 1 by receptor activator of nuclear factor kappaB. | Q40840218 | ||
| P2 purinoceptors: historical perspective and classification. | Q40957044 | ||
| Pore dilation of neuronal P2X receptor channels | Q40960421 | ||
| Membrane topology of an ATP-gated ion channel (P2X receptor). | Q41034616 | ||
| Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65 | Q41067861 | ||
| Signaling by extracellular nucleotides | Q41275320 | ||
| Costimulation requirement for AP-1 and NF-kappa B transcription factor activation in T cells | Q41297074 | ||
| Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk | Q41528266 | ||
| Characterization of ATP receptor which mediates norepinephrine release in PC12 cells | Q41603472 | ||
| Stimulation of DNA synthesis in Jurkat cells by synergistic action between adenine and guanine nucleotides | Q41669198 | ||
| Transcriptional regulation in the immune system: all roads lead to AP-1. | Q41703294 | ||
| Signal transduction through NF-kappa B. | Q41724478 | ||
| Lipopolysaccharide induces expression of tumour necrosis factor alpha in rat brain: inhibition by methylprednisolone and by rolipram | Q41822027 | ||
| ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage | Q43509047 | ||
| MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression | Q43559710 | ||
| Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells | Q43606058 | ||
| Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts | Q43701646 | ||
| Extracellular ATP and ADP activate transcription factor NF-kappa B and induce endothelial cell apoptosis | Q47688328 | ||
| ATP-stimulated activation of the mitogen-activated protein kinases through ionotrophic P2X2 purinoreceptors in PC12 cells. Difference in purinoreceptor sensitivity in two PC12 cell lines | Q47762014 | ||
| Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation | Q48270190 | ||
| Activation of the P2Z/P2X7 receptor in human lymphocytes produces a delayed permeability lesion: involvement of phospholipase D. | Q53937218 | ||
| Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures. | Q54142919 | ||
| Common DNA binding site for Fos protein complexesand transcription factor AP-1 | Q57963290 | ||
| Increased Proliferation Rate of Lymphoid Cells Transfected with the P2X7ATP Receptor | Q61764030 | ||
| The prejunctional inhibitory effect of suramin on neuromuscular transmission in vitro | Q62900088 | ||
| ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood | Q73086270 | ||
| Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis | Q73731212 | ||
| Metabotropic receptors for ATP and UTP: exploring the correspondence between native and recombinant nucleotide receptors | Q77743544 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P1104 | number of pages | 12 | |
| P304 | page(s) | 1549-1560 | |
| P577 | publication date | 2002-11-06 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B. | |
| P478 | volume | 278 |
| Q40563721 | A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury |
| Q39876397 | A P2X ion channel-triggered NF-kappaB pathway enhances TNF-alpha-induced IL-8 expression in airway epithelial cells |
| Q40547060 | A P2X7 receptor stimulates plasma membrane trafficking in the FRTL rat thyrocyte cell line. |
| Q40256464 | A role for P2X7 in microglial proliferation |
| Q28513626 | A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death |
| Q46151092 | ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells |
| Q24647504 | ATP stimulates GRK-3 phosphorylation and beta-arrestin-2-dependent internalization of P2X7 receptor |
| Q40529184 | Acidic ATP activates lymphocyte outwardly rectifying chloride channels via a novel pathway |
| Q42515667 | Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain |
| Q40623576 | Activation of P2X7 purinoceptor-stimulated TGF-β1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2 |
| Q34232228 | Activation of the Transcription Factor FosB/Activating Protein-1 (AP-1) Is a Prominent Downstream Signal of the Extracellular Nucleotide Receptor P2RX7 in Monocytic and Osteoblastic Cells* |
| Q40103919 | Activation of transcription factors by extracellular nucleotides in immune and related cell types. |
| Q40243474 | Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways |
| Q34539873 | Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. |
| Q108591190 | Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus |
| Q40506943 | Are second messengers crucial for opening the pore associated with P2X7 receptor? |
| Q36378777 | AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1/2 |
| Q37283804 | Autocrine regulation of T-cell activation by ATP release and P2X7 receptors |
| Q51982094 | CD21 and CD62L shedding are both inducible via P2X7Rs. |
| Q39269818 | Cell cooperation and role of the P2X₇ receptor in pulmonary inflammation induced by nanoparticles. |
| Q36173797 | Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2 |
| Q37203208 | Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking |
| Q35952737 | Cellular distribution and functions of P2 receptor subtypes in different systems |
| Q39805034 | Corneal protection with high-molecular-weight hyaluronan against in vitro and in vivo sodium lauryl sulfate-induced toxic effects |
| Q40038313 | Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation |
| Q50092377 | Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production |
| Q41863256 | Different properties of P2X(7) receptor in hippocampal and cortical astrocytes |
| Q54571172 | ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons. |
| Q36661625 | Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor |
| Q44042518 | Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X₇ receptor |
| Q50448979 | Emodin regulates bone remodeling by inhibiting osteoclastogenesis and stimulating osteoblast formation. |
| Q28513377 | Exacerbation of experimental autoimmune encephalomyelitis in P2X7R-/- mice: evidence for loss of apoptotic activity in lymphocytes |
| Q54207642 | Expression of P2X7 ATP receptor mediating the IL8 and CCL20 release in human periodontal ligament stem cells. |
| Q40505934 | Expression of P2X7 in human hematopoietic cell lines and leukemia patients. |
| Q44689603 | Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi. |
| Q46391153 | Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells |
| Q33247913 | Fluoroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis |
| Q36168847 | G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation |
| Q81506676 | Gene interactions in depression: pathways out of darkness |
| Q37414770 | Hypoxia Attenuates Purinergic P2X Receptor-Induced Inflammatory Gene Expression in Brainstem Microglia |
| Q39974738 | In vitro modulation of preservative toxicity: high molecular weight hyaluronan decreases apoptosis and oxidative stress induced by benzalkonium chloride. |
| Q58915144 | Increased NTPDase activity in lymphocytes during experimental sepsis |
| Q39706258 | Inhibition of ATP-induced macrophage death by emodin via antagonizing P2X7 receptor |
| Q23914895 | Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappa B, and serine and tyrosine phosphorylation of Ikappa B-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophages |
| Q83421779 | Investigation of protective effects of sodium hyaluronate eyedrop against corneal epithelial disorders using an electrophysiological method |
| Q40339355 | Involvement of de novo ceramide biosynthesis in macrophage death induced by activation of ATP-sensitive P2X7 receptor |
| Q43051770 | Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells |
| Q50952674 | MED1101: a new dialdehydic compound regulating P2×7 receptor cell surface expression in U937 cells. |
| Q38015845 | Microglial microvesicle secretion and intercellular signaling. |
| Q46929110 | Mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways |
| Q57773165 | Molecular and Cellular Mechanisms of Ectodomain Shedding |
| Q36210626 | Molecular and cellular mechanisms of ectodomain shedding |
| Q46756073 | N-Arylpiperazine modified analogues of the P2X7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts |
| Q39966619 | Na+ modulates anion permeation and block of P2X7 receptors from mouse parotid glands. |
| Q37135526 | New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders |
| Q28513396 | Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation |
| Q36174261 | Nucleotide receptor signalling and the generation of reactive oxygen species |
| Q34021603 | Opposing effects of P2X(7) and P2Y purine/pyrimidine-preferring receptors on proliferation of astrocytes induced by fibroblast growth factor-2: implications for CNS development, injury, and repair |
| Q42947303 | Oxidized ATP inhibits T-cell-mediated autoimmunity. |
| Q37135491 | P2 purinergic receptor modulation of cytokine production |
| Q39600738 | P2 receptor-mediated signaling in mast cell biology |
| Q36439708 | P2 receptors: intracellular signaling |
| Q42265737 | P2X(7) Receptors in Neurological and Cardiovascular Disorders |
| Q40138343 | P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. |
| Q36173773 | P2X(7) receptor: Death or life? |
| Q36606127 | P2X(7) receptors: properties and relevance to CNS function |
| Q39499956 | P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment |
| Q40647790 | P2X7 receptor activates extracellular signal-regulated kinases ERK1 and ERK2 independently of Ca2+ influx |
| Q53244593 | P2X7 receptor positively regulates MyD88-dependent NF-κB activation. |
| Q38512772 | P2X7 receptor-dependent ATP-induced shedding of CD27 in mouse lymphocytes. |
| Q80142412 | P2X7 receptor-dependent cell death is modulated during murine T cell maturation and mediated by dual signaling pathways |
| Q28512178 | P2X7 receptors regulate NKT cells in autoimmune hepatitis |
| Q46815034 | Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis |
| Q33687124 | Preservation of differentiation and clonogenic potential of human hematopoietic stem and progenitor cells during lyophilization and ambient storage |
| Q44723151 | Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. |
| Q46947721 | Protective effect of short-term treatment with parathyroid hormone 1-34 on oxidative stress is involved in insulin-like growth factor-I and nuclear factor erythroid 2-related factor 2 in rat bone marrow derived mesenchymal stem cells |
| Q36489231 | Purinergic P2Y2 Receptor Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: NEW AP-1 TRANSCRIPTION FACTOR SITE AND NEGATIVE REGULATOR. |
| Q37218614 | Purinergic receptor antagonism prevents cold preservation-induced cell death independent of cellular ATP levels |
| Q36492634 | Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression |
| Q37518937 | Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes. |
| Q28071636 | Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus? |
| Q46692503 | Rapid effects of 1alpha,25(OH)2D3 in resting human peripheral blood mononuclear cells |
| Q42445872 | Reevaluation of the normal epidermal calcium gradient, and analysis of calcium levels and ATP receptors in Hailey-Hailey and Darier epidermis. |
| Q36752954 | Regulation of immune response by P2X7 receptor. |
| Q43054542 | Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels |
| Q33236096 | Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells |
| Q40326074 | Src tyrosine kinases mediate crystalline silica-induced NF-kappaB activation through tyrosine phosphorylation of IkappaB-alpha and p65 NF-kappaB in RAW 264.7 macrophages |
| Q81203710 | Suppressive effects of Lithospermum erythrorhizon extracts on lipopolysaccharide-induced activation of AP-1 and NF-kappaB via mitogen-activated protein kinase pathways in mouse macrophage cells |
| Q35691962 | The P2X(7) receptor regulates proteoglycan expression in the corneal stroma |
| Q55717414 | The P2X7 receptor: a key player in immune-mediated bone loss? |
| Q28584701 | The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes |
| Q36752948 | The role of NKT cells in animal models of autoimmune hepatitis |
| Q35468810 | Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions |
| Q84153023 | p65/RelA-Ser529 NF-κB subunit phosphorylation induces autophagic astroglial death (Clasmatodendrosis) following status epilepticus |
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