Converging populations of f-actin promote breakage of associated microtubules to spatially regulate microtubule turnover in migrating cells.

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Converging populations of f-actin promote breakage of associated microtubules to spatially regulate microtubule turnover in migrating cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-9822(02)01276-9
P8608Fatcat IDrelease_zlzrqndmgjfy7i3ecbp3b2z7rm
P698PubMed publication ID12445381

P50authorClare WatermanQ29887928
Wendy SalmonQ64681567
P2093author name stringStephanie L Gupton
P2860cites workRho-stimulated contractility drives the formation of stress fibers and focal adhesionsQ24671788
Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmillingQ24680491
Microtubule polymerization dynamicsQ28259930
Identification of Novel Graded Polarity Actin Filament Bundles in Locomoting Heart Fibroblasts: Implications for the Generation of Motile ForceQ29029215
Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cellsQ30477543
Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cellsQ31977083
Positive feedback interactions between microtubule and actin dynamics during cell motilityQ33536505
Microtubules remodel actomyosin networks in Xenopus egg extracts via two mechanisms of F-actin transportQ33911046
Dual-wavelength fluorescent speckle microscopy reveals coupling of microtubule and actin movements in migrating cells.Q34137480
Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth conesQ34137487
How microtubules get fluorescent specklesQ34169200
The importance of lattice defects in katanin-mediated microtubule severing in vitroQ34178001
Regulation of microtubule-associated proteins.Q34387412
New directions for fluorescent speckle microscopy.Q34952832
Tubulin dynamics in cultured mammalian cellsQ36212188
Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmillingQ36273880
Mobility of cytoplasmic and membrane-associated actin in living cells.Q36306376
Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASpQ36316569
Region-specific microtubule transport in motile cellsQ36326451
Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimesQ36379999
Antagonistic forces generated by myosin II and cytoplasmic dynein regulate microtubule turnover, movement, and organization in interphase cellsQ37109838
Cytoskeletal integrity in interphase cells requires protein phosphatase activityQ37308359
Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxolQ40987335
Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundlesQ41279298
Distribution of microtubule organizing centers in migrating sheets of endothelial cellsQ41367440
Role of protein kinase C in the phosphorylation of cardiac myosin light chain 2Q42811533
Assembling an actin cytoskeleton for cell attachment and movementQ58009796
Calyculin A and okadaic acid: inhibitors of protein phosphatase activityQ69337324
Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recoveryQ71843966
Regional regulation of microtubule dynamics in polarized, motile cellsQ77896174
P433issue22
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)1891-1899
P577publication date2002-11-01
P1433published inCurrent BiologyQ1144851
P1476titleConverging populations of f-actin promote breakage of associated microtubules to spatially regulate microtubule turnover in migrating cells
P478volume12

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cites work (P2860)
Q24322612ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity
Q28186936ACF7: an essential integrator of microtubule dynamics
Q57464867Actin-microtubule crosstalk in cell biology
Q33290040Analysis of microtubule curvature
Q30488181Anterograde microtubule transport drives microtubule bending in LLC-PK1 epithelial cells.
Q28565648Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules
Q39427116Buckling behavior of individual and bundled microtubules.
Q42631349Buckling of Microtubules on a 2D Elastic Medium
Q30479241Calyculin A, an enhancer of myosin, speeds up anaphase chromosome movement
Q36321439Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin
Q41104454Centrosome centering and decentering by microtubule network rearrangement
Q56872948Co-Entangled Actin-Microtubule Composites Exhibit Tunable Stiffness and Power-Law Stress Relaxation
Q29615212Conserved microtubule-actin interactions in cell movement and morphogenesis
Q42767552Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites.
Q92256175Eukaryotic Cell Dynamics from Crawlers to Swimmers
Q37639040Fidgetin regulates cultured astrocyte migration by severing tyrosinated microtubules at the leading edge
Q35870286Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane.
Q30490189Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge
Q92709483Interaction of microtubules and actin during the post-fusion phase of exocytosis
Q36635435Intermediate filament dynamics: What we can see now and why it matters
Q34229194Investigation of in vivo microtubule and stress fiber mechanics with laser ablation
Q30495394Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
Q50556215Kojic acid, a secondary metabolite from Aspergillus sp., acts as an inducer of macrophage activation
Q64888627Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis.
Q30437741Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.
Q46816570Mesenchymal Cell Invasion Requires Cooperative Regulation of Persistent Microtubule Growth by SLAIN2 and CLASP1.
Q36412237Microtubule transport in the axon: Re-thinking a potential role for the actin cytoskeleton
Q93372366Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration
Q30651023Microtubule-dependent transport and dynamics of vimentin intermediate filaments
Q39306156Microtubules acquire resistance from mechanical breakage through intralumenal acetylation
Q38152747Microtubules and actin crosstalk in cell migration and division
Q30480404Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement
Q92264658Microtubules in cell migration
Q27314598Microtubules self-repair in response to mechanical stress.
Q27025216Molecular pathways regulating mitotic spindle orientation in animal cells
Q30489963Myosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration
Q35942363Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells
Q34952832New directions for fluorescent speckle microscopy.
Q30476791Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy.
Q59257822Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis
Q51911109Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics.
Q41849642Protrusion and actin assembly are coupled to the organization of lamellar contractile structures
Q30476429Recovery, visualization, and analysis of actin and tubulin polymer flow in live cells: a fluorescent speckle microscopy study
Q34204472Regulation of leading edge microtubule and actin dynamics downstream of Rac1
Q52096698Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow.
Q30480570Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast
Q36448322Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent speckle microscopy
Q35195296The minus end in sight
Q35281262The role of Rho GTPase proteins in CNS neuronal migration
Q27317432Transient Pinning and Pulling: A Mechanism for Bending Microtubules
Q48914394Visualization and quantification of vesicle trafficking on a three-dimensional cytoskeleton network in living cells

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