| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Courtney R LaValle | Q116792962 |
| John S. Lazo | Q56901074 | ||
| Elizabeth R Sharlow | Q62070128 | ||
| Peter Wipf | Q29447250 | ||
| P2093 | author name string | Q Jane Wang | |
| Kara M George | |||
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu | Q22009498 | ||
| Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases | Q24290476 | ||
| Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network | Q24290905 | ||
| E-cadherin phosphorylation by protein kinase D1/protein kinase C{mu} is associated with altered cellular aggregation and motility in prostate cancer | Q24294197 | ||
| Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation | Q24297827 | ||
| Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2 | Q24298735 | ||
| Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis | Q24309609 | ||
| An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation | Q78112212 | ||
| Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu | Q78208164 | ||
| Mitochondrial ROS--radical detoxification, mediated by protein kinase D | Q79382273 | ||
| Protein kinase D: activation for Golgi carrier formation | Q81083701 | ||
| Targeted therapies for pancreatic cancer | Q83603961 | ||
| Protein kinase D-mediated anterograde membrane trafficking is required for fibroblast motility | Q42832109 | ||
| A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase | Q43217182 | ||
| Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells | Q43273887 | ||
| Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu. | Q43566235 | ||
| Inhibition of protein kinase D by resveratrol | Q43832304 | ||
| Putative conventional protein kinase C inhibitor Gödecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes | Q44028929 | ||
| Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. | Q44198663 | ||
| Protein kinase C nu/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonists | Q44391310 | ||
| Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor | Q45310564 | ||
| Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C. | Q46603822 | ||
| Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation. | Q46659681 | ||
| Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion | Q46746848 | ||
| Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing | Q47744848 | ||
| p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells | Q50336697 | ||
| Cell biology. Slick recruitment to the Golgi. | Q52125289 | ||
| Identification of MMP-1 as a putative breast cancer predictive marker by global gene expression analysis. | Q54665746 | ||
| p38delta and PKD1: kinase switches for insulin secretion. | Q54771180 | ||
| Intracellular Location and Cell Context-Dependent Function of Protein Kinase D | Q59748398 | ||
| Immunohistochemical studies of protein kinase D (PKD) 2 expression in malignant human lymphomas | Q60690450 | ||
| PKCμ prevents CD95-mediated apoptosis and enhances proliferation in pancreatic tumour cells | Q61813133 | ||
| A New Kid on the Block | Q63303130 | ||
| Protein kinase C mu is down-regulated in androgen-independent prostate cancer | Q73668139 | ||
| Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta -D-arabinofuranosylcytosine and other genotoxic agents | Q73675920 | ||
| Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot | Q24310778 | ||
| Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis | Q24314902 | ||
| PKCu is a novel, atypical member of the protein kinase C family | Q24329258 | ||
| The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins. | Q24537123 | ||
| Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5 | Q24561772 | ||
| Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network | Q24605796 | ||
| Basal cell carcinoma | Q24677030 | ||
| Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration | Q24679541 | ||
| A gene-expression signature as a predictor of survival in breast cancer | Q27860945 | ||
| Molecular portraits of human breast tumours | Q28032461 | ||
| Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D | Q28140180 | ||
| Protein kinase D: an intracellular traffic regulator on the move | Q28215892 | ||
| ONCOMINE: a cancer microarray database and integrated data-mining platform | Q28255103 | ||
| Protein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells | Q28594706 | ||
| Cancer statistics, 2009 | Q29547625 | ||
| Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility | Q29618423 | ||
| A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo | Q30495531 | ||
| A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. | Q31149618 | ||
| Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation | Q31440867 | ||
| Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. | Q33280165 | ||
| Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone | Q33373235 | ||
| Phosphorylation-dependent protein kinase D activation | Q33590831 | ||
| CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway | Q33615492 | ||
| Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility | Q33866583 | ||
| Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications | Q33899708 | ||
| Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species | Q34097117 | ||
| Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor | Q34496547 | ||
| Gastric cancer in Korea | Q34528139 | ||
| Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. | Q34552323 | ||
| Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 2. | Q34652231 | ||
| Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2. | Q34778930 | ||
| PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions | Q41062713 | ||
| Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities | Q41064697 | ||
| Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. | Q41078558 | ||
| Protein kinase D: a novel target for diacylglycerol and phorbol esters | Q41112298 | ||
| Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes | Q41173469 | ||
| Assessment of brain tumor cell motility in vivo and in vitro | Q41352261 | ||
| Regulation of cardiac stress signaling by protein kinase d1. | Q41496270 | ||
| Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C. | Q41728142 | ||
| Protein kinase D activation by mutations within its pleckstrin homology domain. | Q42448861 | ||
| Protein-kinase-Cmu expression correlates with enhanced keratinocyte proliferation in normal and neoplastic mouse epidermis and in cell culture | Q42467593 | ||
| Identification of molecular apocrine breast tumours by microarray analysis. | Q42478400 | ||
| Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. | Q42558480 | ||
| Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. | Q42795887 | ||
| Bryostatin 1 induces biphasic activation of protein kinase D in intact cells | Q42797815 | ||
| Protein kinase D1-mediated phosphorylation and subcellular localization of beta-catenin. | Q42804258 | ||
| HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression | Q42813213 | ||
| Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation | Q42824508 | ||
| Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells | Q42826316 | ||
| Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells | Q42831514 | ||
| The Ena/VASP enigma | Q34997188 | ||
| p38MAPK inhibition prevents disease in pemphigus vulgaris mice | Q35036492 | ||
| Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration. | Q35564850 | ||
| Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain | Q35731354 | ||
| Protein kinase D signaling | Q36035199 | ||
| Dimeric PKD regulates membrane fission to form transport carriers at the TGN | Q36274555 | ||
| PKD at the crossroads of DAG and PKC signaling | Q36470256 | ||
| Requirement of protein kinase D1 for pathological cardiac remodeling | Q36498485 | ||
| Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. | Q36693824 | ||
| Derepression of pathological cardiac genes by members of the CaM kinase superfamily | Q36705529 | ||
| Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation | Q36741576 | ||
| Inhibition of Akt pathways in the treatment of prostate cancer | Q36807494 | ||
| Class IIa histone deacetylases: regulating the regulators | Q36908414 | ||
| Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association | Q36984917 | ||
| Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling | Q37011824 | ||
| Significance of chemoprevention for prostate cancer development: experimental in vivo approaches to chemoprevention | Q37027624 | ||
| Invadopodia: at the cutting edge of tumour invasion. | Q37158821 | ||
| VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis | Q37353597 | ||
| Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review. | Q37381629 | ||
| Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer | Q37412311 | ||
| Structure-based design of molecular cancer therapeutics | Q37429223 | ||
| Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology | Q37548226 | ||
| Targeting the PI3K/AKT pathway for the treatment of prostate cancer | Q37564760 | ||
| Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis | Q37572455 | ||
| Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like | Q39830921 | ||
| Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion | Q39879745 | ||
| Characterization of cortactin as an in vivo protein kinase D substrate: interdependence of sites and potentiation by Src. | Q39911482 | ||
| Characterization of EVL-I as a protein kinase D substrate | Q39918982 | ||
| Bryostatin 1 modulates beta-catenin subcellular localization and transcription activity through protein kinase D1 activation | Q39944257 | ||
| Protein kinase D is a positive regulator of Bit1 apoptotic function | Q39950598 | ||
| Protein kinase D1 (PKD1) influences androgen receptor (AR) function in prostate cancer cells | Q39964999 | ||
| Beta-catenin mediates alteration in cell proliferation, motility and invasion of prostate cancer cells by differential expression of E-cadherin and protein kinase D1. | Q40057893 | ||
| PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells | Q40119640 | ||
| Requirement of protein kinase D tyrosine phosphorylation for VEGF-A165-induced angiogenesis through its interaction and regulation of phospholipase Cgamma phosphorylation | Q40246685 | ||
| Protein kinase D distribution in normal human epidermis, basal cell carcinoma and psoriasis | Q40305222 | ||
| Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes | Q40322638 | ||
| Requirement of Protein Kinase Cμ Activation and Calpain-mediated Proteolysis for Arachidonic Acid-stimulated Adhesion of MDA-MB-435 Human Mammary Carcinoma Cells to Collagen Type IV | Q40618385 | ||
| Neurotensin induces protein kinase C-dependent protein kinase D activation and DNA synthesis in human pancreatic carcinoma cell line PANC-1. | Q40742637 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 183-192 | |
| P577 | publication date | 2010-05-24 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | Protein kinase D as a potential new target for cancer therapy | |
| P478 | volume | 1806 |
| Q64095593 | A Review of Curcumin and Its Derivatives as Anticancer Agents |
| Q28483837 | A targeted library screen reveals a new inhibitor scaffold for protein kinase D |
| Q35824690 | A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells |
| Q59340800 | Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma |
| Q37706498 | Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells |
| Q47617811 | Computational design of new protein kinase D 1 (PKD1) inhibitors: homology-based active site prediction, energy-optimized pharmacophore, docking and database screening. |
| Q91693060 | Curcumin and Its Derivatives as Potential Therapeutic Agents in Prostate, Colon and Breast Cancers |
| Q34241833 | Curcumin attenuates β-catenin signaling in prostate cancer cells through activation of protein kinase D1. |
| Q40082136 | Deletion of protein kinase D1 in osteoprogenitor cells results in decreased osteogenesis in vitro and reduced bone mineral density in vivo |
| Q30428751 | Design, Synthesis, and Biological Evaluation of PKD Inhibitors |
| Q36042028 | Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12. |
| Q39122407 | Different regulation of physiological and tumor angiogenesis in zebrafish by protein kinase D1 (PKD1). |
| Q41489966 | Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues. |
| Q37890712 | Emerging roles of protein kinase D1 in cancer |
| Q55456779 | Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells. |
| Q36798446 | Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms. |
| Q61800787 | High PKD2 predicts poor prognosis in lung adenocarcinoma via promoting Epithelial-mesenchymal Transition |
| Q64094683 | Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in�vitro |
| Q30414963 | In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenografts |
| Q36084010 | Inducible silencing of protein kinase D3 inhibits secretion of tumor-promoting factors in prostate cancer |
| Q35036725 | Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk |
| Q35005813 | New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells |
| Q33837268 | Oncogenic Protein Kinase D3 Regulating Networks in Invasive Breast Cancer |
| Q64242547 | Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer |
| Q35536358 | Opposing growth regulatory roles of protein kinase D isoforms in human keratinocytes |
| Q36674635 | PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells |
| Q34743753 | Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling |
| Q26747243 | Protein Kinase D1 Signaling in Angiogenic Gene Expression and VEGF-Mediated Angiogenesis |
| Q39098659 | Protein kinase C in cancer: The top five unanswered questions. |
| Q36014643 | Protein kinase D promotes plasticity-induced F-actin stabilization in dendritic spines and regulates memory formation. |
| Q24301421 | Protein kinase D regulates RhoA activity via rhotekin phosphorylation |
| Q35239280 | Protein kinase D signaling: multiple biological functions in health and disease |
| Q54982246 | Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy. |
| Q37652940 | Protein kinase D1 has a key role in wound healing and skin carcinogenesis |
| Q33694680 | Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation |
| Q37025429 | Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro |
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| Q33753441 | Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways. |
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| Q42434225 | The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells |
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| Q92241884 | [Protein kinase D1 regulates the growth and metabolism of oral squamous carcinoma cells in tumor microenvironment] |
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