Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing.

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Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-3495(98)77555-1
P932PMC publication ID1299740
P698PubMed publication ID9675167

P50authorWilly WriggersQ64675783
P2093author name stringK Schulten
P2860cites workEnzyme-Catalyzed Phosphoryl Transfer ReactionsQ22255662
Crystal structure of the kinesin motor domain reveals a structural similarity to myosinQ24601210
Switches, latches, and amplifiers: common themes of G proteins and molecular motorsQ24671028
Comparison of simple potential functions for simulating liquid waterQ26778447
Atomic structure of the actin:DNase I complexQ27685392
Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteinsQ27686798
Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysisQ27729301
X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-Q27729777
Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopyQ27731257
Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragmentQ27731308
Structural determinants for activation of the alpha-subunit of a heterotrimeric G proteinQ27731423
The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma SQ27731495
Three-dimensional structure of myosin subfragment-1: a molecular motorQ27731679
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolutionQ27732650
VMD: visual molecular dynamicsQ27860554
Reversal in the direction of movement of a molecular motorQ28248501
Molecular motors: structural adaptations to cellular functionsQ28251722
Evidence that the head of kinesin is sufficient for force generation and motility in vitroQ28633264
The Energy Landscapes and Motions of ProteinsQ29616408
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformationQ29618283
Slow-cooling protocols for crystallographic refinement by simulated annealingQ29620956
Water-protein interactions: theory and experimentQ31168441
Kinesin ATPase: rate-limiting ADP releaseQ33643312
Stability and dynamics of G-actin: back-door water diffusion and behavior of a subdomain 3/4 loopQ33907127
Delayed start-up of kinesin-driven microtubule gliding following inhibition by adenosine 5'-[beta,gamma-imido]triphosphateQ33928067
Bead movement by single kinesin molecules studied with optical tweezersQ33957127
Structural mechanisms for domain movements in proteinsQ34342565
Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysisQ35600643
Pathway of processive ATP hydrolysis by kinesin.Q35757837
Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd proteinQ36343722
Protein hydration elucidated by molecular dynamics simulationQ36574680
Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR.Q36719980
Crystal structure of active elongation factor Tu reveals major domain rearrangementsQ36769294
Direct observation of kinesin stepping by optical trapping interferometryQ36774439
Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubulesQ36817748
Three-dimensional cryoelectron microscopy of 16-protofilament microtubules: structure, polarity, and interaction with motor proteinsQ36857189
Going mobile: microtubule motors and chromosome segregationQ37700220
Equilibrium studies of kinesin-nucleotide intermediatesQ38358875
Origins of reversed directionality in the ncd molecular motorQ40790854
Realistic simulations of native-protein dynamics in solution and beyondQ40832976
Kinesin and NCD, two structural cousins of myosinQ41102794
The movement of kinesin along microtubulesQ41117807
The kinetic cycles of myosin, kinesin, and dyneinQ41117818
A model for the microtubule-Ncd motor protein complex obtained by cryo-electron microscopy and image analysisQ41633666
Three-dimensional structure of functional motor proteins on microtubulesQ41633942
A novel brain ATPase with properties expected for the fast axonal transport motorQ43626542
Different axoplasmic proteins generate movement in opposite directions along microtubules in vitroQ44192316
Identification and characterization of a gene encoding a kinesin-like protein in DrosophilaQ44542698
A solution for the best rotation to relate two sets of vectorsQ45034417
Chemomechanical cycle of kinesin differs from that of myosin.Q46040213
Movement of microtubules by single kinesin moleculesQ46085669
Crystal structure of the motor domain of the kinesin-related motor ncd.Q46107252
Microtubule interaction site of the kinesin motorQ46134467
Crystallization and preliminary structural studies of the ncd motor domainQ46216642
Organelle transport along microtubules - the role of KIFsQ47986431
The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor.Q52239281
Protein domain movements: detection of rigid domains and visualization of hinges in comparisons of atomic coordinates.Q52256509
The Drosophila claret segregation protein is a minus-end directed motor molecule.Q52449568
Expression, purification, ATPase properties, and microtubule-binding properties of the ncd motor domain.Q52536622
Nucleotide-dependent angular change in kinesin motor domain bound to tubulin.Q52537440
CHARMM: A program for macromolecular energy, minimization, and dynamics calculationsQ53340989
Flap opening in HIV-1 protease simulated by 'activated' molecular dynamics.Q53849991
Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometryQ57873906
Failure of a single-headed kinesin to track parallel to microtubule protofilamentsQ59053953
Weak and strong states of kinesin and ncdQ71082943
Kinesin and myosin: molecular motors with similar enginesQ71337280
Kinetic mechanism of kinesin motor domainQ71715633
Mechanism of microtubule kinesin ATPaseQ71715637
Structural studies of kinesin-nucleotide intermediatesQ71825183
ADP release is the rate-limiting step of the MT activated ATPase of non-claret disjunctional and kinesinQ71958168
Interacting head mechanism of microtubule-kinesin ATPaseQ71973549
Identification of kinesin neck region as a stable alpha-helical coiled coil and its thermodynamic characterizationQ73106831
Hydrophilicity of cavities in proteinsQ73365493
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectsimulated annealingQ863783
P304page(s)646-661
P577publication date1998-08-01
P1433published inBiophysical JournalQ2032955
P1476titleNucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing
P478volume75

Reverse relations

cites work (P2860)
Q4163211715 A resolution model of the monomeric kinesin motor, KIF1A.
Q37088138A comparative study of motor-protein motions by using a simple elastic-network model
Q36492504A kinesin switch I arginine to lysine mutation rescues microtubule function
Q34453133A look into kinesin's powerhouse
Q41609096Allosteric control of kinesin's motor domain by tubulin: a molecular dynamics study
Q24635112Analysis of the interaction of the Eg5 Loop5 with the nucleotide site
Q33866615Directional motility of kinesin motor proteins
Q34173949Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures
Q36426352Flavin Binding to the Deca-heme Cytochrome MtrC: Insights from Computational Molecular Simulation
Q73280054His(73), often methylated, is an important structural determinant for actin. A mutagenic analysis of HIS(73) of yeast actin
Q37288252Mapping the structural and dynamical features of kinesin motor domains
Q34983426Microtubule-kinesin interface mutants reveal a site critical for communication
Q30782396Molecular dynamics simulations of the NGF-TrkA domain 5 complex and comparison with biological data
Q28353333Molecular dynamics study of the energetic, mechanistic, and structural implications of a closed phosphate tube in ncd
Q33609780Motor proteins of the kinesin family. Structures, variations, and nucleotide binding sites
Q30483024Myosin dynamics on the millisecond time scale
Q31142431Ordered conformational change in the protein backbone: prediction of conformationally variable positions from sequence and low-resolution structural data
Q34350367Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: myosin versus kinesin.
Q27636199Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules
Q33536507Structures of kinesin and kinesin-microtubule interactions

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