Neuronal estrogen receptor-alpha mediates neuroprotection by 17beta-estradiol

scientific article

Neuronal estrogen receptor-alpha mediates neuroprotection by 17beta-estradiol is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JCBFM.2009.258
P932PMC publication ID2949189
P698PubMed publication ID20010956
P5875ResearchGate publication ID40688446

P50authorMarkus SchwaningerQ1636480
P2093author name stringGünther Schütz
Sajjad Muhammad
Tim M Wintermantel
Jochen Ludwig
Anne Regnier-Vigouroux
Joachim G Elzer
P2860cites workEstrogen response element-independent estrogen receptor (ER)-alpha signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice.Q48087122
Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptorsQ48157309
NF-kappaB is activated and promotes cell death in focal cerebral ischemiaQ48220270
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.Q48338905
Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility.Q48394948
Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemiaQ49103976
Neuroprotection by Estrogens in a Mouse Model of Focal Cerebral Ischemia and in Cultured Neurons: Evidence for a Receptor-Independent Antioxidative MechanismQ56699187
Antiinflammatory effects of estrogen on microglial activationQ73027691
Stroke in estrogen receptor-alpha-deficient miceQ73505612
Identification and functional characterization of the mannose receptor in astrocytesQ77794223
Selective estrogen receptor modulators (SERMs) for the brain: current status and remaining challenges for developing NeuroSERMsQ81440420
Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemiaQ81452814
IKK mediates ischemia-induced neuronal deathQ28281709
Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouseQ30642163
Estrogen actions in the central nervous systemQ33658556
Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activityQ33849756
Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injuryQ34114102
Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female miceQ34430361
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiolQ35235007
Neuroprotection by estrogen in animal models of global and focal ischemiaQ35679179
The HMGB1 receptor RAGE mediates ischemic brain damageQ36134557
Crossroads of estrogen receptor and NF-kappaB signalingQ36163226
Estrogens and experimental ischemic stroke: a systematic reviewQ36377761
Role of astrocytes in estrogen-mediated neuroprotectionQ36548906
Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women.Q36621171
Mitochondrial effects of estrogen are mediated by estrogen receptor alpha in brain endothelial cells.Q37115403
Dose-related neuroprotective versus neurodamaging effects of estrogens in rat cerebral ischemia: a systematic analysisQ37490810
17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localizationQ40441268
Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor geneQ41275521
Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.Q43489000
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.Q44554898
Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemiaQ44897727
Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemiaQ44904426
A semiautomated method for measuring brain infarct volume.Q45954002
Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death.Q46427696
Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell deathQ46983619
P4510describes a project that usesImageJQ1659584
P433issue5
P921main subjectestrogenQ277954
P1104number of pages8
P304page(s)935-942
P577publication date2009-12-16
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleNeuronal estrogen receptor-alpha mediates neuroprotection by 17beta-estradiol
P478volume30