NMDA channel gating is influenced by a tryptophan residue in the M2 domain but calcium permeation is not altered

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NMDA channel gating is influenced by a tryptophan residue in the M2 domain but calcium permeation is not altered is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-3495(00)76488-5
P932PMC publication ID1301130
P698PubMed publication ID11053122

P2093author name stringClements JD
Howitt SM
Buck DP
P2860cites workChannel kinetics determine the time course of NMDA receptor-mediated synaptic currentsQ48919293
NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteinesQ48921111
Coupling of permeation and gating in an NMDA-channel pore mutantQ48968453
Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channelQ49016266
Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines.Q50760890
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.Q51769623
Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channelQ52072490
Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9‐aminoacridineQ54179283
Nonuniform probability of glutamate release at a hippocampal synapseQ58191305
The selectivity filter of the N-methyl-D-aspartate receptor: a tryptophan residue controls block and permeation of Mg2+Q74536227
Molecular diversity of the NMDA receptor channelQ28585736
Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channelsQ33554934
A single tryptophan on M2 of glutamate receptor channels confers high permeability to divalent cationsQ34040307
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neuronesQ34255679
Molecular cloning and characterization of the rat NMDA receptorQ34762781
Interactions between two divalent ion binding sites in N-methyl-D-aspartate receptor channelsQ35947358
Ionic permeability characteristics of the N-methyl-D-aspartate receptor channelQ36411434
Excitatory amino acid receptors in the vertebrate central nervous systemQ38316536
Molecular mechanisms controlling calcium entry through AMPA-type glutamate receptor channelsQ40423316
The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in cultureQ41253548
Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytesQ41470703
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptorQ41603790
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunitQ41649334
Different mechanisms of Ca2+ transport in NMDA and Ca2+-permeable AMPA glutamate receptor channels.Q41900225
Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neuronesQ43591139
Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neuronesQ45263360
Structural determinants of barium permeation and rectification in non-NMDA glutamate receptor channelsQ46259431
Fractional contribution of calcium to the cation current through glutamate receptor channelsQ48264301
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)2454-2462
P577publication date2000-11-01
P1433published inBiophysical JournalQ2032955
P1476titleNMDA channel gating is influenced by a tryptophan residue in the M2 domain but calcium permeation is not altered
P478volume79

Reverse relations

cites work (P2860)
Q37193138A novel alcohol-sensitive position in the N-methyl-D-aspartate receptor GluN2A subunit M3 domain regulates agonist affinity and ion channel gating
Q40692616A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating
Q46165547Common binding site for externally and internally applied AMPA receptor channel blockers
Q92724855De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases
Q40498654NR2 subunit-dependence of NMDA receptor channel block by external Mg2+.
Q33719620Optocontrol of glutamate receptor activity by single side-chain photoisomerization

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