| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1006/EXCR.2000.5143 |
| P698 | PubMed publication ID | 11237531 |
| P2093 | author name string | Kemp CJ | |
| Payne SR | |||
| Philipp-Staheli J | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | haploinsufficiency | Q852654 |
| P304 | page(s) | 148-168 | |
| P577 | publication date | 2001-03-01 | |
| P1433 | published in | Experimental Cell Research | Q1524289 |
| P1476 | title | p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer. | |
| P478 | volume | 264 |
| Q36205587 | A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesis |
| Q34635679 | A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization |
| Q27325410 | A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1 |
| Q34324068 | A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression |
| Q38745881 | AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27. |
| Q37143195 | ARTD1 regulates cyclin E expression and consequently cell-cycle re-entry and G1/S progression in T24 bladder carcinoma cells. |
| Q35685819 | Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death |
| Q53448904 | Activated Akt as an indicator of prognosis in gastric cancer. |
| Q39068932 | Adhesion to fibronectin induces p27(Kip1) nuclear accumulation through down-regulation of Jab1 and contributes to cell adhesion-mediated drug resistance (CAM-DR) in RPMI 8,226 cells |
| Q34880437 | Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region |
| Q42442038 | Alteration of the PATCHED locus in superficial bladder cancer |
| Q33222173 | Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis |
| Q35039199 | Altered tumor biology and tumorigenesis in irradiated and chemical carcinogen-treated single and combined connexin32/p27Kip1-deficient mice |
| Q51898909 | An age-and-cyclin-structured cell population model for healthy and tumoral tissues. |
| Q28829867 | Animal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for 100 Years |
| Q50542290 | Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma |
| Q26753162 | Autophagy and Apoptotic Crosstalk: Mechanism of Therapeutic Resistance in HER2-Positive Breast Cancer |
| Q40691704 | BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases |
| Q34551213 | BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein |
| Q35683173 | CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis |
| Q47662413 | CacyBP/SIP inhibits the migration and invasion behaviors of glioblastoma cells through activating Siah1 mediated ubiquitination and degradation of cytoplasmic p27. |
| Q35939817 | Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma |
| Q47761897 | Cancer: Kip moving |
| Q74115954 | Cancer: new-age tumour suppressors |
| Q33898315 | Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors. |
| Q50089799 | Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1. |
| Q53223025 | Combined loss of p21(waf1/cip1) and p27(kip1) enhances tumorigenesis in mice. |
| Q39435905 | Consequences of interrupted Rheb-to-AMPK feedback signaling in tuberous sclerosis complex and cancer |
| Q37683696 | Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT |
| Q94361807 | Cycle on Wheels: Is APP Key to the AppBp1 Pathway? |
| Q33869104 | Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients. |
| Q81168177 | Deficiency in the gap junction protein connexin32 alters p27Kip1 tumor suppression and MAPK activation in a tissue-specific manner |
| Q34167777 | Deregulated degradation of the cdk inhibitor p27 and malignant transformation. |
| Q24648025 | Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer |
| Q57562801 | Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice |
| Q40498683 | Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2. |
| Q35893635 | Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype |
| Q79333437 | Distinct roles for p53, p27Kip1, and p21Cip1 during tumor development |
| Q28218378 | Down-regulation of Id-1 expression is associated with TGF beta 1-induced growth arrest in prostate epithelial cells |
| Q55471655 | Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells. |
| Q40546151 | EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation. |
| Q34276145 | ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells |
| Q36308092 | Expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27Kip1 in hepatocellular carcinoma |
| Q40511335 | Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma |
| Q49789112 | Frequent and differential mutations of the CYLD gene in basal cell salivary neoplasms: linkage to tumor development and progression |
| Q47159773 | Functional characterization of a CDKN1B mutation in a Sardinian kindred with multiple endocrine neoplasia type 4 (MEN4). |
| Q54321696 | Gefitinib induces cytoplasmic translocation of the CDK inhibitor p27 and its binding to a cleaved intermediate of caspase 8 in non-small cell lung cancer cells. |
| Q64283563 | Genetics and Epigenetics of Gastroenteropancreatic Neuroendocrine Neoplasms |
| Q90540463 | Genetics of Pituitary Tumours |
| Q46369286 | Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas |
| Q24679314 | Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans |
| Q40601158 | Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines |
| Q28589954 | Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors |
| Q34103991 | High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle |
| Q53628339 | Higher potency of the synthetic retinoid MX3350-1 compared to the natural all-trans-retinoic acid in modulation of cell cycle and induction of apoptosis in head and neck squamous carcinoma cells. |
| Q39900954 | Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src. |
| Q47450539 | Histochemical examination of periodontal junctional epithelium in p21/p27 double knockout mice |
| Q39127532 | Homeodomain transcription factor Phox2a, via cyclic AMP-mediated activation, induces p27Kip1 transcription, coordinating neural progenitor cell cycle exit and differentiation |
| Q34627179 | Hunk is required for HER2/neu-induced mammary tumorigenesis |
| Q36117812 | Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells |
| Q47235754 | Hypoxia regulation of the cell cycle in malignant melanoma: putative role for the cyclin-dependent kinase inhibitor p27. |
| Q41905296 | Identification of a novel heterozygous truncation mutation in exon 1 of ARHGAP29 in an Indian subject with nonsyndromic cleft lip with cleft palate |
| Q34350229 | Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells. |
| Q39659322 | Inflammatory Mediators of Esophagitis Alter p27Kip1 Expression in Esophageal Epithelial Cells |
| Q33740876 | Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer |
| Q40683948 | Inhibitory effect of p27KIP1 gene transfer on head and neck squamous cell carcinoma cell lines |
| Q34928606 | Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells |
| Q39971767 | Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation |
| Q42628891 | Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage |
| Q39164530 | Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression |
| Q44740065 | Intercellular trafficking and enhanced in vivo antitumour activity of a non-virally delivered P27-VP22 fusion protein. |
| Q36902777 | Intestinal-specific activatable Myb initiates colon tumorigenesis in mice. |
| Q47322344 | Loss of heterozygosity at 12p13 and loss of p27KIP1 protein expression contribute to melanoma progression |
| Q53131281 | Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas. |
| Q36546501 | Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression |
| Q37015708 | Low Expression of CDK5 and p27 Are Associated with Poor Prognosis in Patients with Gastric Cancer |
| Q34273369 | MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation |
| Q37787565 | MEN-4 and other multiple endocrine neoplasias due to cyclin-dependent kinase inhibitors (p27Kip1 and p18INK4C) mutations |
| Q53103786 | MEN4 and CDKN1B mutations: the latest of the MEN syndromes. |
| Q30472107 | Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells. |
| Q47173251 | Misexpression of the cyclin-dependent kinase inhibitor ICK1/KRP1 in single-celled Arabidopsis trichomes reduces endoreduplication and cell size and induces cell death |
| Q36528831 | Mouse chromosome engineering for modeling human disease |
| Q34554750 | Multiparameter analyses of cell cycle regulatory proteins in human breast cancer: a key to definition of separate pathways in tumorigenesis |
| Q36545440 | Mutant AKT1-E17K is oncogenic in lung epithelial cells |
| Q34337413 | Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia. |
| Q35057304 | New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? |
| Q24293592 | Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells |
| Q44396851 | Nonmonotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose. |
| Q44119076 | P21 functions to maintain quiescence of p27-deficient hepatocytes |
| Q47303812 | P21Waf1/Cip1 and p27Kip1 are correlated with the development and invasion of prolactinoma. |
| Q35596549 | P27kip1 regulates the apoptotic response of gastric epithelial cells to Helicobacter pylori |
| Q52955313 | PI3K/AKT pathway-mediated regulation of p27(Kip1) is associated with cell cycle arrest and apoptosis in cervical cancer. |
| Q34150579 | PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization |
| Q44043140 | Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice |
| Q33496190 | Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma |
| Q53356205 | Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. |
| Q80538864 | Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed-Sternberg cells |
| Q92578250 | Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors |
| Q34202288 | Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human |
| Q37198026 | Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states |
| Q35810123 | Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature |
| Q43812543 | Redox regulation of cell proliferation by pyrrolidine dithiocarbamate in murine thymoma cells transplanted in vivo |
| Q35968417 | Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors? |
| Q35165927 | Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma |
| Q33641523 | Retracted: Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27Kip1 Upregulation |
| Q51620108 | Rewiring of the apoptotic TGF-β-SMAD/NFκB pathway through an oncogenic function of p27 in human papillary thyroid cancer. |
| Q24669893 | Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation |
| Q35745139 | Role of the CDK inhibitor p27 (Kip1) in mammary development and carcinogenesis: insights from knockout mice |
| Q36004665 | Sak/Plk4 and mitotic fidelity |
| Q35232589 | Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. |
| Q34982783 | Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis |
| Q35070668 | Skp2 is necessary for Myc-induced keratinocyte proliferation but dispensable for Myc oncogenic activity in the oral epithelium |
| Q36956900 | Skp2 is over-expressed in breast cancer and promotes breast cancer cell proliferation |
| Q35739846 | Stopping and going with p27kip1. |
| Q35905281 | Systems biology and the molecular circuits of cancer |
| Q47159993 | The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability |
| Q36953585 | The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. |
| Q39703205 | The RNA binding protein Musashi1 regulates apoptosis, gene expression and stress granule formation in urothelial carcinoma cells |
| Q40317015 | The Wnt pathway destabilizes adherens junctions and promotes cell migration via β-catenin and its target gene cyclin D1. |
| Q47422868 | The cyclin‐dependent kinase inhibitors p27Kip1 and p21Cip1 are not essential in T cell anergy |
| Q28572579 | The gap junction-independent tumor-suppressing effect of connexin 43 |
| Q35079447 | The many forks in FOXO's road |
| Q36022283 | The novel protective role of P27 in MLN4924-treated gastric cancer cells |
| Q44007453 | The phosphorylation site located in the A region of retinoic X receptor alpha is required for the antiproliferative effect of retinoic acid (RA) and the activation of RA target genes in F9 cells |
| Q34668320 | The prognostic molecular markers in hepatocellular carcinoma |
| Q44406747 | The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition |
| Q36661884 | Transcriptional control of cell-cycle quiescence during C. elegans development |
| Q28389231 | Tumor suppressor and hepatocellular carcinoma |
| Q36252762 | Tumor suppressor genetics |
| Q39019302 | Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation |
| Q46968824 | Vasopressin receptor subtype 2 activation increases cell proliferation in the renal medulla of AQP1 null mice. |
| Q35571368 | When protein destruction runs amok, malignancy is on the loose |
| Q36647928 | p110δ PI3 kinase pathway: emerging roles in cancer |
| Q34181774 | p27 as a target for cancer therapeutics |
| Q44289554 | p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development |
| Q34013292 | p27 kip1 haplo-insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK activation |
| Q39016914 | p27 modulates tropism of mesenchymal stem cells toward brain tumors |
| Q43444997 | p27KIP1 expression in gastric cancer: differential pathways in the histological subtypes associated with Helicobacter pylori infection |
| Q40795456 | p27Kip1 modulates cell migration through the regulation of RhoA activation. |
| Q33713330 | p27Kip1deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process |
| Q36421086 | p27kip1 deficiency impairs G2/M arrest in response to DNA damage, leading to an increase in genetic instability |
| Q37803487 | p27kip1: a new multiple endocrine neoplasia gene? |
| Q35800865 | p27kip1: a target for tumor therapies? |
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