Cysteine residues in the nucleotide binding domains regulate the conductance state of CFTR channels

scientific article

Cysteine residues in the nucleotide binding domains regulate the conductance state of CFTR channels is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0006-3495(02)75484-2
P932PMC publication ID1301931
P698PubMed publication ID11867445
P5875ResearchGate publication ID11495594

P2093author name stringRon R Kopito
Melissa A Harrington
P2860cites workStructure of a voltage-dependent K+ channel beta subunitQ27618988
Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channelsQ27625246
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activityQ28142263
ATPase activity of the cystic fibrosis transmembrane conductance regulatorQ28854569
The "megaprimer" method of site-directed mutagenesisQ29620742
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)Q33970197
Slow conversions among subconductance states of cystic fibrosis transmembrane conductance regulator chloride channelQ34017151
CFTR channels in immortalized human airway cellsQ34208228
Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysisQ35269834
ATP-dependent bacterial transporters and cystic fibrosis: analogy between channels and transportersQ35323989
Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating schemeQ36412100
Regulation of CFTR Cl- channel gating by ATP binding and hydrolysisQ37238263
Interdomain but not intermolecular interactions observed in CFTR channelsQ40771268
The two halves of CFTR form a dual-pore ion channelQ40890137
Redox reagents and divalent cations alter the kinetics of cystic fibrosis transmembrane conductance regulator channel gatingQ40928853
A single conductance pore for chloride ions formed by two cystic fibrosis transmembrane conductance regulator moleculesQ40967502
Novel pore-lining residues in CFTR that govern permeation and open-channel blockQ41022138
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis.Q41081260
Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance stateQ41269444
Membrane topology of a cysteine-less mutant of human P-glycoproteinQ41380800
Defective regulation of outwardly rectifying Cl- channels by protein kinase A corrected by insertion of CFTRQ41608893
Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis geneQ41669744
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosisQ41714520
Nucleoside triphosphates are required to open the CFTR chloride channel.Q41769807
Pyridine nucleotide redox potential modulates cystic fibrosis transmembrane conductance regulator Cl- conductanceQ42068756
Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating.Q42674364
Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion SelectivityQ43847410
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channelQ43911618
Transformation of rat cells by DNA of human adenovirus 5Q44464709
Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis.Q46017118
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteinsQ46621436
Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycleQ46797528
N-Acetyl-L-cysteine and its derivatives activate a Cl- conductance in epithelial cellsQ49021235
NO+, NO, and NO- donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulfide formation.Q51605840
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.Q53938455
Regulation of CFTR channel gatingQ58112756
Effect of Deleting the R Domain on CFTR-Generated Chloride ChannelsQ67694895
Inhibition of vacuolar H(+)-ATPase by disulfide bond formation between cysteine 254 and cysteine 532 in subunit AQ72403613
Covalent inhibitors of P-glycoprotein ATPase activityQ72671369
Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulatorQ73770423
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1278-1292
P577publication date2002-03-01
P1433published inBiophysical JournalQ2032955
P1476titleCysteine residues in the nucleotide binding domains regulate the conductance state of CFTR channels
P478volume82

Reverse relations

cites work (P2860)
Q30445827Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione.
Q36981796Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats
Q36379776Insight in eukaryotic ABC transporter function by mutation analysis
Q45204993Intracellular thiol-mediated modulation of epithelial sodium channel activity
Q41466794Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH.
Q34989488Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function
Q38035816Overview of pyridine nucleotides review series.
Q41888706Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells
Q57282398Oxidative stress, autophagy and airway ion transport
Q42670820State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator
Q45199722Stimulation of colonic anion secretion by monochloramine: action sites
Q33750252The H-loop in the second nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator is required for efficient chloride channel closing
Q43249070The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease
Q38913048Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications
Q24633363Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel

Search more.