Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans

scientific article

Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.00313-10
P932PMC publication ID2950526
P698PubMed publication ID20679492

P50authorJanet QuinnQ30502817
P2093author name stringAlessandra da Silva Dantas
Lars P Erwig
Brian A Morgan
Deborah A Smith
Donna M Maccallum
Miranda J Patterson
P2860cites workKilling activity of neutrophils is mediated through activation of proteases by K+ fluxQ24292504
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.Q24533236
Transcriptional response of Candida albicans upon internalization by macrophagesQ24563309
Global analysis of protein localization in budding yeastQ27653962
A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activationQ27930196
AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamilyQ27930958
Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycleQ27934271
Getting started with yeastQ28131602
Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance studyQ29616607
Epidemiology of invasive candidiasis: a persistent public health problemQ29616758
Nonfilamentous C. albicans mutants are avirulentQ29617839
Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systemsQ31096762
Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene.Q32065060
Apoptosis induced by environmental stresses and amphotericin B in Candida albicans.Q33716986
Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infectionQ33768787
Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicansQ33859372
Isogenic strain construction and gene mapping in Candida albicans.Q33961115
The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicansQ33991085
Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions.Q33991500
Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfideQ34313529
The distinct morphogenic states of Candida albicansQ34329798
Fungal histidine kinasesQ34467977
Transcription factors regulating the response to oxidative stress in yeastQ34611235
Hydrogen peroxide sensing and signalingQ34619087
A hyphal-specific chitin synthase gene (CHS2) is not essential for growth, dimorphism, or virulence of Candida albicansQ35561196
Critical role of DNA checkpoints in mediating genotoxic-stress-induced filamentous growth in Candida albicansQ35650832
Superoxide Dismutases inCandida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-inducedSOD5GeneQ35796206
Candida albicans response regulator gene SSK1 regulates a subset of genes whose functions are associated with cell wall biosynthesis and adaptation to oxidative stressQ36370450
Macrophages in resistance to candidiasisQ36574240
Property differences among the four major Candida albicans strain cladesQ37122002
Identification of the Candida albicans Cap1p regulon.Q37232388
Nitrosative and oxidative stress responses in fungal pathogenicityQ37310228
Role of reactive oxygen species in fungal cellular differentiationsQ37317330
Thioredoxin deficiency causes the constitutive activation of Yap1, an AP-1-like transcription factor in Saccharomyces cerevisiae.Q38320265
Gcn4 co-ordinates morphogenetic and metabolic responses to amino acid starvation in Candida albicansQ39659009
The moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicansQ39726874
The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.Q39751926
REDOX reaction at ASK1-Cys250 is essential for activation of JNK and induction of apoptosisQ39830506
The mitogen-activated protein kinase homolog HOG1 gene controls glycerol accumulation in the pathogenic fungus Candida albicansQ39843038
A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicansQ39968804
Differential susceptibility of mitogen-activated protein kinase pathway mutants to oxidative-mediated killing by phagocytes in the fungal pathogen Candida albicansQ40161812
GFP as a quantitative reporter of gene regulation in Candida albicans.Q40522408
Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2)O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosisQ41312477
Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicansQ42022199
Protein A‐tagging for purification of native macromolecular complexes from Candida albicansQ42613228
A single MAPKKK regulates the Hog1 MAPK pathway in the pathogenic fungus Candida albicansQ42629264
Hydrogen peroxide induces hyphal differentiation in Candida albicansQ42834383
Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxidesQ43944924
Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulenceQ44213608
Stage-specific gene expression of Candida albicans in human bloodQ44352765
A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinaseQ44957864
Cell cycle arrest during S or M phase generates polarized growth via distinct signals in Candida albicansQ46642597
CIp10, an efficient and convenient integrating vector for Candida albicansQ47885729
Gene disruption in Candida albicans using a synthetic, codon-optimised Cre-loxP systemQ48128113
In vivo characterization of a thioredoxin h target protein defines a new peroxiredoxin family.Q52535625
Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood.Q52939255
Analysis of the oxidative stress regulation of the Candida albicans transcription factor, Cap1p.Q54049038
New thioredoxins and glutaredoxins as electron donors of 3'-phosphoadenylylsulfate reductaseQ74602382
NADPH oxidaseQ75301478
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. IV. ISOLATION AND CHARACTERIZATION OF THIOREDOXIN, THE HYDROGEN DONOR FROM ESCHERICHIA COLI BQ77147031
Cap1p is involved in multiple pathways of oxidative stress response in Candida albicansQ82871230
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectCandida albicansQ310443
P304page(s)4550-4563
P577publication date2010-08-02
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans
P478volume30

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cites work (P2860)
Q37267170Candida albicans Dbf4-dependent Cdc7 kinase plays a novel role in the inhibition of hyphal development
Q46250263Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis
Q30531267Candida albicans induces arginine biosynthetic genes in response to host-derived reactive oxygen species
Q37967076Candida albicans morphogenesis and host defence: discriminating invasion from colonization.
Q34534684Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress
Q35651454Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans
Q46229761Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans
Q38668190Enzymatic Mechanisms Involved in Evasion of Fungi to the Oxidative Stress: Focus on Scedosporium apiospermum
Q31034172Glutathione utilization by Candida albicans requires a functional glutathione degradation (DUG) pathway and OPT7, an unusual member of the oligopeptide transporter family
Q34098943Identification of a novel response regulator, Crr1, that is required for hydrogen peroxide resistance in Candida albicans
Q87194125Increased oxidative stress tolerance results in general stress tolerance in Candida albicans independently of stress-elicited morphological transitions
Q35774249Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans.
Q28273024Interactions of fungal pathogens with phagocytes
Q64249750Investigating Common Pathogenic Mechanisms between and Different Strains of for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification
Q89017603Ions released from a S-PRG filler induces oxidative stress in Candida albicans inhibiting its growth and pathogenicity
Q30503045Live imaging of disseminated candidiasis in zebrafish reveals role of phagocyte oxidase in limiting filamentous growth
Q35604809MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans
Q39772640Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency
Q34165499Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.
Q92430842Multi-omics Analyses Reveal Synergistic Carbohydrate Metabolism in Streptococcus mutans-Candida albicans Mixed-Species Biofilms
Q39999162Mycobacterium tuberculosis phosphoenolpyruvate carboxykinase is regulated by redox mechanisms and interaction with thioredoxin
Q27313707Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
Q38268265Novel insights into host-fungal pathogen interactions derived from live-cell imaging
Q35080863Orthologues of the anaphase-promoting complex/cyclosome coactivators Cdc20p and Cdh1p are important for mitotic progression and morphogenesis in Candida albicans
Q35255440Oxidative stress responses in the human fungal pathogen, Candida albicans
Q41570443Peroxide sensing and signaling in the Sporothrix schenckii complex: an in silico analysis to uncover putative mechanisms regulating the Hog1 and AP-1 like signaling pathways
Q26774292Peroxiredoxins in Regulation of MAPK Signalling Pathways; Sensors and Barriers to Signal Transduction
Q30806103Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis
Q35025538Possible involvement of nitric oxide and reactive oxygen species in glucose deprivation-induced activation of transcription factor rst2.
Q31077054Reactive oxygen species in the signaling and adaptation of multicellular microbial communities
Q54981599Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs.
Q52647762Repurposing Auranofin, Ebselen, and PX-12 as Antimicrobial Agents Targeting the Thioredoxin System.
Q46247342Repurposing an inhibitor of ribosomal biogenesis with broad anti-fungal activity
Q50790715Roles of Cch1 and Mid1 in morphogenesis, oxidative stress response and virulence in Candida albicans.
Q46334030Stress Adaptation.
Q38172488Stress adaptation in a pathogenic fungus
Q92408951Stress-Activated Protein Kinases in Human Fungal Pathogens
Q36259715The Iron-Dependent Regulation of the Candida albicans Oxidative Stress Response by the CCAAT-Binding Factor.
Q53693123The calcium channel blocker verapamil inhibits oxidative stress response in Candida albicans.
Q38238627The fission yeast Schizosaccharomyces pombe as a model to understand how peroxiredoxins influence cell responses to hydrogen peroxide
Q92498424The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species
Q40104482The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation
Q51774314Therapeutic jackpots lie within the reach of multiscale and integrated mycological research.
Q88645413Thioredoxin and Glutaredoxin Systems Required for Oxidative Stress Resistance, Fungicide Sensitivity, and Virulence of Alternaria alternata
Q40492170Thioredoxins are involved in the activation of the PMK1 MAP kinase pathway during appressorium penetration and invasive growth in Magnaporthe oryzae
Q38077110Thriving within the host: Candida spp. interactions with phagocytic cells
Q37406652Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape
Q42502266cAMP-independent signal pathways stimulate hyphal morphogenesis in Candida albicans

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