Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug

scientific article

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1987PNAS...84..551B
P356DOI10.1073/PNAS.84.2.551
P932PMC publication ID304247
P698PubMed publication ID3540968
P5875ResearchGate publication ID19620891

P50authorPhilippe BeauneQ43274168
Patrick DansetteQ57419431
P2093author name stringJ C Homberg
C Amar
D Mansuy
J P Leroux
M Finck
L Kiffel
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A new anti-liver-kidney microsome antibody (anti-LKM2) in tienilic acid-induced hepatitisQ28366441
Oxidative metabolism of halothane in the production of altered hepatocyte membrane antigens in acute halothane-induced hepatic necrosisQ28366927
A new cytochrome in liver microsomesQ33972584
Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodiesQ42228823
Induction by drugs of hepatitis and autoantibodies to cell organelles: significance and interpretationQ44812711
A simple and sensitive assay of 7-ethoxycoumarin deethylationQ46527161
Immunochemical evidence of trifluoroacetylated cytochrome P-450 in the liver of halothane-treated rats.Q51820174
Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes.Q51826467
Metabolic hydroxylation of the thiophene ring: Isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and ratQ57747339
Unexplained hepatitis following halothaneQ67449270
Immunoquantification of epoxide hydrolase and cytochrome P-450 isozymes in fetal and adult human liver microsomesQ68940141
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresisQ70237548
Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reactionQ70274827
Purification and characterization of six cytochrome P-450 isozymes from human liver microsomesQ70458093
Purification of a new cytochrome P-450 from human liver microsomesQ93569208
Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatographyQ93689719
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
drug-induced hepatitisQ10294943
autoantibodyQ785022
P1104number of pages5
P304page(s)551-555
P577publication date1987-01-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleHuman anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug
P478volume84