Astrocyte‐derived glutathione attenuates hemin‐induced apoptosis in cerebral microvascular cells

scientific article published on November 15, 2010

Astrocyte‐derived glutathione attenuates hemin‐induced apoptosis in cerebral microvascular cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/GLIA.21055
P953full work available at URLhttps://europepmc.org/articles/pmc2951495?pdf=render
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fglia.21055
https://doi.org/10.1002/glia.21055
https://europepmc.org/articles/PMC2951495
https://europepmc.org/articles/PMC2951495?pdf=render
https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.21055
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20737478/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20737478/pdf/?tool=EBI
P932PMC publication ID2951495
P698PubMed publication ID20737478
P5875ResearchGate publication ID45828677

P50authorKrishnan M DhandapaniQ87676804
Nagendra SinghQ87994384
P2093author name stringSangeetha Sukumari-Ramesh
Melissa D. Laird
Cargill H. Alleyne
John R. Vender
P2860cites workEvidence for apoptosis after intercerebral hemorrhage in rat striatumQ28577314
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxideQ29547245
The cytotoxic effects of diesel exhaust particles on human pulmonary artery endothelial cells in vitro: role of active oxygen speciesQ31969247
Glutathione metabolism and its implications for healthQ34301684
Astrocyte-mediated control of cerebral blood flowQ34481040
Acute cerebral vascular injury after subarachnoid hemorrhage and its prevention by administration of a nitric oxide donorQ34616246
Novel therapies for intracerebral hemorrhageQ35742572
Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalystQ36087920
Inflammation after intracerebral hemorrhageQ36620460
Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative StressQ38355236
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysisQ38358203
Caspase-8, -12, and -3 activation by 7-ketocholesterol in retinal neurosensory cellsQ40166160
Antioxidant defense of the brain: a role for astrocytesQ41683285
Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogeneQ41725147
The pathogenetic and prognostic significance of blood-brain barrier damage at the acute stage of aneurysmal subarachnoid haemorrhage. Clinical and experimental studiesQ42437100
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Transgenic CuZn-superoxide dismutase inhibits NO synthase induction in experimental subarachnoid hemorrhageQ42506864
Experimental intracerebral hemorrhage: effect of lysed erythrocytes on brain edema and blood-brain barrier permeabilityQ42524627
Enhancement of glutathione-dependent haemin degradation by ascorbic acidQ44094186
Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutaseQ44128126
Neuroprotective effects of estrogen and tamoxifen in vitro: a facilitative role for glia?Q44460333
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.Q44755335
Focal astrocyte loss is followed by microvascular damage, with subsequent repair of the blood-brain barrier in the apparent absence of direct astrocytic contactQ44766213
Neurovascular protection reduces early brain injury after subarachnoid hemorrhageQ45025356
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Hemin-induced necroptosis involves glutathione depletion in mouse astrocytesQ46427149
Evolution of the inflammatory response in the brain following intracerebral hemorrhage and effects of delayed minocycline treatmentQ46963922
Size matters: hemorrhage volume as an objective measure to define significant intracranial hemorrhage associated with thrombolysisQ47290691
Effects of S-nitrosoglutathione on acute vasoconstriction and glutamate release after subarachnoid hemorrhageQ48121929
Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factorsQ48124419
A peroxynitrite-dependent pathway is responsible for blood-brain barrier permeability changes during a central nervous system inflammatory response: TNF-alpha is neither necessary nor sufficientQ48161920
Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide.Q48246861
Apoptosis and white matter injury in preterm infantsQ48652249
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.Q50515282
Hemin: levels in experimental subarachnoid hematoma and effects on dissociated vascular smooth-muscle cells.Q51659384
Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage.Q53541143
Molecular signatures of vascular injury are associated with early growth of intracerebral hemorrhage.Q53603615
Astrocytes induce blood–brain barrier properties in endothelial cellsQ57318253
Glutathione efflux from cultured astrocytesQ71464500
Nuclear factor-kappaB and cell death after experimental intracerebral hemorrhage in ratsQ73149820
Glutathione reverses endothelial damage from peroxynitrite, the byproduct of nitric oxide degradation, in crystalloid cardioplegiaQ73199828
Complement activation in the brain after experimental intracerebral hemorrhageQ73853504
Spontaneous intracerebral hemorrhageQ73862624
Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recoveryQ74171209
Inducible nitric oxide synthase expression in human cerebral infarctsQ74632190
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectglutathioneQ116907
astrocyteQ502961
microvesselQ6840468
P304page(s)1858-1870
P577publication date2010-11-01
2010-11-15
P1433published inGliaQ15716658
P1476titleAstrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells
Astrocyte‐derived glutathione attenuates hemin‐induced apoptosis in cerebral microvascular cells
P478volume58

Reverse relations

cites work (P2860)
Q90321028A Combined Proteomics and Bioinformatics Approach Reveals Novel Signaling Pathways and Molecular Targets After Intracerebral Hemorrhage
Q36463567Astrocyte-specific expression of survivin after intracerebral hemorrhage in mice: a possible role in reactive gliosis?
Q38170068Astrogliosis: a target for intervention in intracerebral hemorrhage?
Q41988533DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress.
Q37283380Dietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cells
Q55312063Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis.
Q42176313Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
Q38218093Heme on innate immunity and inflammation
Q47740571Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death
Q53423640Hemin protects against oxygen-glucose deprivation-induced apoptosis activation via neuroglobin in SH-SY5Y cells.
Q38819908Hemoglobin-Improved Protection in Cultured Cerebral Cortical Astroglial Cells: Inhibition of Oxidative Stress and Caspase Activation
Q35854679High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4
Q40937139NAC changes the course of cerebral small vessel disease in SHRSP and reveals new insights for the meaning of stases - a randomized controlled study
Q37657438Necrostatin-1 reduces neurovascular injury after intracerebral hemorrhage.
Q40312201Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis
Q39217821Regulation of HFE expression by poly(ADP-ribose) polymerase-1 (PARP1) through an inverted repeat DNA sequence in the distal promoter
Q39629878Response of Rat Retinal Capillary Pericytes and Endothelial Cells to Glucose
Q34963885STAT3 regulates MMP3 in heme-induced endothelial cell apoptosis
Q37885608Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke.
Q91677833The impact of endothelial cell death in the brain and its role after stroke: A systematic review

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